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Probiotics for Agriculture

December 10th, 2013
Total interviews: 75
The Pivot Team

Karsten Temme
CEO

Alvin Tamsir
CSO

Emily Tung
Researcher

John Cumbers
Mentor
Week 1
•
•
•
Academic labs
UC Davis Soil Ecology group •
SynBerc
AgBio industry leaders

Science – lab POC
Field trials
Regulatory engagement
Establish AgBio
partnership for sales
channels
• Inoculant distribution
• Customer service
• Public relations

• Reduced risk of loss in
drought
• Improved yield
• Organic
• Lower human and
equipment costs

• Direct relationships
• Self service (3rd party
purchases)
• On-farm interactions
• Potential collaborative
relationships

Dow Corning
Bayer
Monsanto
TBD:
- Fermentation scale up
- Packaging and prep

Farmers
• Corn
• Wheat
• Rice

Corporate farm
Family farm
•
•
•
•
•
•

Synthetic biology IP
Next gen sequencing IP
Proprietary microbes
Regulatory awareness
Sales staff
Production staff and
facility

• Direct sales
• Local supplier / grain
elevator
• Seed companies
• Fertilizer companies
• State fairs

• Inoculant purchases
• Next-gen sequencing diagnostic
• Licensing royalties

Organic
Conventional
Crops

Treatments

GM
Strains

Natural
Strains

Probiotic
Mixture

Natural
Strains

• Germinated in sterile greenhouse conditions
• CA dominates US tomato cultivation

Fermented
Metabolites
Week 1

• Reduced risk of loss in
drought
• Improved yield
• Organic
• Lower human and
equipment costs

Week 5

Farmers
• Corn
• Wheat
• Rice
• Tomato seed companies
• Tomato nurseries
Corporate farm
Family farm

Organic
Conventional

• Tomato farmers
• Seed coating companies
Customer archetype
•
•
•
•

Manager of HeinzSeed Global
60+ years of tomato seed breeding
Develops most of top tomato varieties
Looks for new technologies to improve tomato
production
Plant
health
Fruit
quality

Dale Smith
HeinzSeed

Disease
resistance

Yield
Drought
tolerance
Germination
US Commercial Processing Tomato Industry
Acreage:
Location:
Market Size:

300,000 acres
95% in CA
$700M

Break even:
Average:
Highest:

40 tons / acre
48 tons / acre
70 tons / acre

“10% yield improvement would be significant”
Channels and Market Structure
Product Flow
Cash Flow

Seed production

Seed breeders

Seed treatment

Seed distributors
Grading and Processing
Nurseries

Commercial Farms
The MVP

Tomato Seeds

Seed breeders

Seed production

50% market

Seed treatment

Heinz

Value based pricing
Yield Increase - $70M
Current
$700M

$10M

Heinz + Pivot

Value if MVP applied to
Top 10 Varieties of 2013

$7.5M
To Farmers - $35M
$5M
To Greenhouses - $4M
To Seed Breeders - $3M
Pivot (40%) - $28M

$2.5M
Red = Heinz varieties
Building the MVP: Key Metrics
MVP

Now

Q1 2014

Q2 2014

Q3 2014

Greenhouse Trial

Q4 2014

Field Trial

R&D Activites

Milestone

Cost

• Endophyte Isolation

• 500 relevant strains

$30k

• Sequencing and Analytics

• All genomes annotated and scored

$50k

• Selection and Optimization

• 50 high confidence strains

$140k

• Greenhouse Trial

• 10% yield increase

$60k

Personnel: 1 bioinformatician
Partners (done): Greenhouse (UC Berkeley), NGS (Seqmatic), Heinz and Germains
IP: File composition of matter on 50 high confidence strains
Economics: Validate revenue sharing hypotheses, negotiate field trial financing
Week 10
Senior customer endorsement

Operational plan validated
Talent recruited
IP strategy and KOL network
“Proof of Relevance” defined
Timeline and cost to data points
Strategic fit in portfolio validated
Technology confirmed

First pass canvas

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Pivot bio final presentation

  • 1. Probiotics for Agriculture December 10th, 2013 Total interviews: 75
  • 2. The Pivot Team Karsten Temme CEO Alvin Tamsir CSO Emily Tung Researcher John Cumbers Mentor
  • 3. Week 1 • • • Academic labs UC Davis Soil Ecology group • SynBerc AgBio industry leaders Science – lab POC Field trials Regulatory engagement Establish AgBio partnership for sales channels • Inoculant distribution • Customer service • Public relations • Reduced risk of loss in drought • Improved yield • Organic • Lower human and equipment costs • Direct relationships • Self service (3rd party purchases) • On-farm interactions • Potential collaborative relationships Dow Corning Bayer Monsanto TBD: - Fermentation scale up - Packaging and prep Farmers • Corn • Wheat • Rice Corporate farm Family farm • • • • • • Synthetic biology IP Next gen sequencing IP Proprietary microbes Regulatory awareness Sales staff Production staff and facility • Direct sales • Local supplier / grain elevator • Seed companies • Fertilizer companies • State fairs • Inoculant purchases • Next-gen sequencing diagnostic • Licensing royalties Organic Conventional
  • 4. Crops Treatments GM Strains Natural Strains Probiotic Mixture Natural Strains • Germinated in sterile greenhouse conditions • CA dominates US tomato cultivation Fermented Metabolites
  • 5. Week 1 • Reduced risk of loss in drought • Improved yield • Organic • Lower human and equipment costs Week 5 Farmers • Corn • Wheat • Rice • Tomato seed companies • Tomato nurseries Corporate farm Family farm Organic Conventional • Tomato farmers • Seed coating companies
  • 6. Customer archetype • • • • Manager of HeinzSeed Global 60+ years of tomato seed breeding Develops most of top tomato varieties Looks for new technologies to improve tomato production Plant health Fruit quality Dale Smith HeinzSeed Disease resistance Yield Drought tolerance Germination
  • 7. US Commercial Processing Tomato Industry Acreage: Location: Market Size: 300,000 acres 95% in CA $700M Break even: Average: Highest: 40 tons / acre 48 tons / acre 70 tons / acre “10% yield improvement would be significant”
  • 8. Channels and Market Structure Product Flow Cash Flow Seed production Seed breeders Seed treatment Seed distributors Grading and Processing Nurseries Commercial Farms
  • 9. The MVP Tomato Seeds Seed breeders Seed production 50% market Seed treatment Heinz Value based pricing Yield Increase - $70M Current $700M $10M Heinz + Pivot Value if MVP applied to Top 10 Varieties of 2013 $7.5M To Farmers - $35M $5M To Greenhouses - $4M To Seed Breeders - $3M Pivot (40%) - $28M $2.5M Red = Heinz varieties
  • 10. Building the MVP: Key Metrics MVP Now Q1 2014 Q2 2014 Q3 2014 Greenhouse Trial Q4 2014 Field Trial R&D Activites Milestone Cost • Endophyte Isolation • 500 relevant strains $30k • Sequencing and Analytics • All genomes annotated and scored $50k • Selection and Optimization • 50 high confidence strains $140k • Greenhouse Trial • 10% yield increase $60k Personnel: 1 bioinformatician Partners (done): Greenhouse (UC Berkeley), NGS (Seqmatic), Heinz and Germains IP: File composition of matter on 50 high confidence strains Economics: Validate revenue sharing hypotheses, negotiate field trial financing
  • 12. Senior customer endorsement Operational plan validated Talent recruited IP strategy and KOL network “Proof of Relevance” defined Timeline and cost to data points Strategic fit in portfolio validated Technology confirmed First pass canvas

Notas del editor

  1. Updated business model canvas to reflect changes in value props and our discovery of actual customer segment. Moving foward, we wanted to test the product market fit of our core value propositions.