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B11 Enzymes

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Unit B11: Cell Biology (Enzymes) Authored by Michelle Choma © ,[object Object],[object Object],[object Object],[object Object]
PLO’s continued ,[object Object],[object Object],[object Object]
PLO’s continued ,[object Object],[object Object]
And lastly!! ,[object Object]
Terms to Know ,[object Object],[object Object],[object Object]
Metabolism ,[object Object]
 
Enzymes ( E ): ,[object Object]
Enzymes ,[object Object],[object Object],[object Object]
Enzymes ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Enzymes ,[object Object],[object Object],[object Object]
Enzymes ,[object Object],[object Object],[object Object]
Enzymes ,[object Object]
Substrates ( S ) ,[object Object],[object Object],[object Object]
Co-enzymes ,[object Object],[object Object],[object Object]
 
Energy of Activation: ,[object Object],[object Object]
See following graph of Time vs. Energy Level .
 
Energy of Activation ,[object Object],[object Object],[object Object]
“ Induced Fit” Model of Enzymatic Action ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Induced Fit Theory ,[object Object]
 
Steps of the Induced Fit Theory ,[object Object],[object Object]
Steps of the Induced Fit Theory ,[object Object]
Dehydration Synthesis of Monomers
Hydrolysis of a Polymer
Co-enzymes and Vitamins ,[object Object],[object Object]
Co-enzymes/vitamins ,[object Object],[object Object]
Enzymatic Reaction with a Co-enzyme:
 
Effects on Enzyme Activity ,[object Object],[object Object],[object Object]
Factors affecting the rate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
pH ,[object Object],[object Object],[object Object],[object Object]
More Examples of pH ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
pH ,[object Object],[object Object]
 
Interpreting pH vs. Rate of Enzyme Activity graphs :
Interpreting graph ,[object Object],[object Object]
Interpreting pH vs. Rate of Enzyme Activity graphs : ,[object Object]
 
Temperature ,[object Object],[object Object]
Temperature ,[object Object],[object Object],[object Object]
 
Interpreting Temperature vs. Rate of Enzyme Activity graphs : 37
Temperature Vs. Time for O 2 Production
About the graph ,[object Object]
About the graph ,[object Object],[object Object]
[Substrate]
Interpreting Substrate Concentration vs. Rate of Enzyme Activity graph:
About the Substrate graph ,[object Object],[object Object],[object Object],[object Object]
[Enzyme]
About the Enzyme graph ,[object Object]
Competitive Inhibitor ,[object Object],[object Object],[object Object]
Uses---the good, the bad & the ugly! ,[object Object],[object Object],[object Object]
Competitive Inhibitors ,[object Object]
Competitive Inhibitor -E.g. In the following metabolic pathway: E 1 E 2 E 3 A B C D competitive inhibitor ,[object Object]
Competitive Inhibitor
Interesting tidbits ,[object Object],[object Object]
Non-Competitive Inhibitor ,[object Object],[object Object]
Important Note!! ,[object Object]
Inhibitor Effects on Rate of Reaction
 
 
 
Heavy Metals ,[object Object],[object Object],[object Object],[object Object]
Interpreting Addition of Heavy Metals vs. Rate of Enzyme Activity graph:
Temp Vs. Heavy Metal ,[object Object]
Enzyme Activity Labs One molecule of catalase can break 40 million molecules of hydrogen peroxide each second. No wonder so many bubbles!!!
Review
Which line represents an enzyme-catalyzed reaction?
 
 
Experimental Design Using the Scientific Method ,[object Object],[object Object],[object Object]
Experimental Design ,[object Object],[object Object]
Steps of the Scientific Method ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Effects of Thyroxin on Metabolism
Thyroxin ,[object Object],[object Object]
Thyroxin ,[object Object]
Thyroxin ,[object Object],[object Object]
Feedback loop
Thyroid ,[object Object],[object Object],[object Object]
 
 
 
 
Cretinism
Websites ,[object Object],[object Object],[object Object]
Websites ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Websites ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Websites ,[object Object],[object Object],[object Object],[object Object],[object Object]

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