Cell Wall Inhibitors

Cell Wall Inhibitors dr shabeel pn www.hi-dentfinishingschool.blogspot.com

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Structure ,[object Object],[object Object],[object Object],[object Object],[object Object]

thiazolidine ring (A) connected to a b-lactam ring (B), to which is attached a side chain (R).

[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Classification ,[object Object],[object Object],[object Object]

Mechanisms of Drug Actions by Enzyme Inhibition: ,[object Object]

Cell Wall production ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

Figure 45-2. The transpeptidase reaction in Staphylococcus aureus that is inhibited by penicillins and cephalosporins.

Figure 45-3. Comparison of the structure and composition of gram-positive and gram-negative cell walls.

Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object]

Parenteral Administration of Penicillin G ,[object Object],[object Object],[object Object],[object Object]

Distribution . ,[object Object],[object Object]

Excretion ,[object Object],[object Object],[object Object]

Unitage of Penicillin ,[object Object],[object Object],[object Object]

Therapeutic Uses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanisms of Bacterial Resistance to Penicillins ,[object Object],[object Object],[object Object],[object Object],[object Object]

Other resistance mechanisms ,[object Object],[object Object],[object Object]

Adverse effects ,[object Object],[object Object]

Stevens Johnson Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object]

Management of the Patient Potentially Allergic to Penicillin . ,[object Object],[object Object]

Adverse effects cont ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Drug-drug Interactions ,[object Object],[object Object]

Classification of the Penicillins and Summary of Their Pharmacological Properties ,[object Object],[object Object],[object Object]

Cephalosporins ,[object Object],[object Object],[object Object],[object Object]

Cephalosporins First Generation Second Generation Third Generation Fourth Generation * Oral Agent Ceftriaxone Cefuroxime moxalactam Ceftizoxime Cefoxitin Cephradine * Ceftibuten Cefotetan Cephaprin Ceftazidime Ceforanide Cephalothin Cefotaxime Cefonicid Cefelixin * Cefoperaxone Cefamandole Cefazolin Cefepime Cefdinir Cefaclor * Cefadroxil *

First generation cephalosporins: ,[object Object],[object Object],[object Object]

Second generation cephalosporins: ,[object Object],[object Object]

Third generation cephalosporins: ,[object Object],[object Object]

Fourth generation ,[object Object]

Pharmacokinetics ,[object Object],[object Object],[object Object]

Adverse effects ,[object Object],[object Object],[object Object],[object Object],[object Object]

Uses: ,[object Object],[object Object],[object Object],[object Object]

Drug interaction ,[object Object]

Carbapenems and monobactams ,[object Object],[object Object],[object Object]

Imipenem: ,[object Object],[object Object]

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Monobactam ,[object Object],[object Object],[object Object],[object Object]

beta -Lactamase Inhibitors ,[object Object],[object Object],[object Object],[object Object]

Cell Wall Inhibitors

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Cell Wall Inhibitors