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ATHEROSCLEROSIS MORPHOLOGY    &   COMPLICATIONS ,[object Object],[object Object]
 
MORPHOLOGY ,[object Object],[object Object]
-:FATTY STREAK:- ,[object Object],[object Object],[object Object]
 
 
-:ATHEROSCLEROTIC PLAQUE:- ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
CHANGES IN THE ATHEROSCLEROTIC PLAQUE ,[object Object],[object Object],[object Object],[object Object]
RUPTURE
HEMORRHAGE INTO PLAQUE
ATHERO EMBOLISM
ANEURYSMS FORMATION
COMPLICATIONS
-:COMPLICATIONS:- ,[object Object],[object Object],[object Object],[object Object]
Atherosclerotic stenosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ACUTE PLAQUE CHANGE ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EVENTS TRIGGERING CHANGES IN PLAQUE  CONFIGURATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ROLE OF FREE RADICALS (OXIDATIVE STRESS) LDL Oxidised LDL Release of free radicals DAMAGE TO THE ARTERIAL WALL Into macrophages
 
[object Object],[object Object],[object Object]
[object Object],[object Object]
CLINICAL FEATURES ON CORONARY ARTERIES: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ON CAROTID ARTERIES: ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ON PERIPHERAL ARTERIES:
DIAGNOSIS
DIAGNOSIS SEROLOGICAL IMAGING LIPID PROFILE   HbA1c   CRP-HS HOMOCYSTEINE LDL LEVEL LIPOPROTEIN a CT SCAN INTRAVASCULAR ULTRASOUND ANGIOGRAPHY DOPPLER STUDY
TREATMENT
TREATMENT NON-PHARMACEUTICAL PHARMACEUTICAL NON-FAT DIET CESSATION OF SMOKING REGULAR EXERCISE REDUCE ALCOHOL CONSUMPTION Use of  drug surgical
PHARMACOTHERAPY DRUGS FOR REDUCING HYPERCHOLESTROLEMIA STATINS ATORVASTATIN FLUVASTATIN LOVASTATIN PRAVASTATIN SIMVASTATIN ROSUVASTATIN
[object Object],[object Object],[object Object],[object Object],[object Object]
DRUGS FOR REDUCING CLOT FORMATION VITAMIN –K ANTAGONIST WARFARIN ACENOCOUMAROL PHENINDIONE HEPARIN DERIVATIVES HEPARIN FONDAPARINUX INDRAPARINUX DIRECT THROMBIN INHIBITORS ARGATROBAN LEPIRUDIN BIVALURIDIN
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SURGICAL INTERVENTION ,[object Object],[object Object],[object Object],[object Object]
SUMMARY
MORPHOLOGY
MORPHOLOGY
COMPLICATIONS MYOCARDIAL INFARCTION STROKE PERIPHERAL VASCULAR DISEASE ANEURYSM FORMATION
COMPLICATIONS Atherosclerotic stenosis ,[object Object],[object Object],Acute plaque change ,[object Object],[object Object]
 
THANK YOU

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Atherosclerosis Morphology, Complications, and Treatment