No single approach to knowledge classification and access is best for every application. This webinar will help participants choose the right approach(es) to support their own cognitive computing application. The science and engineering of data management for computational efficiency is well-understood. We have algorithms and heuristics to pre-fetch data and instructions and distribute them based on properties of the algorithms, data sets, applications, and system software and hardware. We have decades of experience fine-tuning hardware, networks, operating systems, compilers and applications based on physics. Now we need to start thinking in terms of biology. Fortunately, we don’t have to actually model the 100B neurons or 100-500 trillion synapses in the human brain in hardware or software. We do need a well-specified knowledge model to organize refined data based on how we expect to query and further refine it. What we store constrains which questions a cognitive system may be able to answer. How we organize this knowledge may determine whether our system can answer questions or generate hypotheses efficiently or effectively.