Tracking Drug Shortages with Open APIs and Hedera Hashgraph | Hedera18

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YouTube Video https://youtu.be/1uS2706lO3A Speaker Jim Nasr | VP of Technology and Innovation | Synchrogenix: A Certara Company Abstract This session will develop into the practical considerations and approach taken to develop a large scale distributed ledger technology implementation for tracking drug shortage in the pharma industry, using open API technologies and Hedera Hashgraph. We'll be addressing the rationale and approach for our design and implementation, architectural components, complementary use cases, lessons learned and the roadmap going forward.

Software

Tracking Drug Shortage
With Open APIs &
Hedera Hashgraph
Jim Nasr | @jnasr
jim.nasr@synchrogenix.com
 
10.17.18

“A hungry tapeworm on
the American economy”
Warren Buffet on US healthcare systems - January, 2018

Moore’s Law vs. Eroom’s Law
Moore’s Law: Computing power becomes faster and less expensive over time
Eroom’s Law: https://en.wikipedia.org/wiki/Eroom%27s_law
Eroom’s Law: Drug discovery is becoming slower and more expensive over time
Opportunity  
Mobile 
IoT 
Wearables 
Machine Learning

DNA of Public DLT
Technology
Value Creation
Culture

So, How Does Hedera Help?
Near Real-time
Transaction Transparency Global Scale
Highest Security &
Cryptographic Trust
Fastest
Proof of State
Most Efficient
Consensus
Native Cryptocurrency
(Tokenization)
Development
Flexibility

Emergency Response
Aid Management
Cash Management in Crisis Relief
Public Health Data Surveillance
Dangerous Substance Tracking
Death Certificate Exchange
Opioid Tracking
Population Health Management
Public Health Communication
Inventory Tracking
Inter-agency data exchange
Counterfeit Drug Tracking
Clinical Research Collaboration
Generic Drug Shortage
…
Health and Public Cause Use Cases

Muhammad Ali
“It isn’t the mountains ahead to
climb that wear you out; it’s the
pebble in your shoe”

Use animation to show immediate app responsiveness
Swipe instead of tap
The finger is not accurate...size tap targets appropriately!
Land Grab for Data
Data as currency
Legacy data largely siloed
and non-interoperable
Open technology: “pipes”
to connect data sources

Software as a Theme Park
http://bit.ly/SWThemePark

Constructing the Theme Park…
Functional Layer
Blueprint Layer
DevOps Layer

Software Functions as Open APIs
Microservices (atomic to multifunctional)

Building Software with Open APIs
Data Conversion
API
CDISC Spec
Lookup API
Basic Reporting
API
Data Visualization
API
Process
Monitoring API
PhUSE Spec
Lookup API
DS Anonymization
API
Scorecard
API Advanced
Reporting API
OP React UI
Components

Relevant Open Technologies…
Early Preview: www.OpenPharma.io

Generic Drug Supply Shortage POC
Active Pharmaceutical
Ingredient (API) Manufacturer
Factory A
Factory B
Hedera
Network
Each API manufacturer can
be declared on the network.
Each API manufacturer can declare a
list of factories and their status (active
or not). Each factory needs to declare
as well their manufactured ingredients.
Distributor
Each distributor can be declared on
the network and defined their stock
availability on ingredients.
Pharmacy
Each pharmacy can be declared on
the network and defined their stock
availability on ingredients.
Group Purchasing
Organization
FDA inspectors can publish their
inspection reports on factory to the
network to identify potential
inactivity of some factories.
FDA Inspection
Team
FDA Regulator
Team
FDA regulators can access data real
time on stock availability, factories
status, inspection reports through a
reporting system to make decision.

Application Architecture
Manufacturer
GPO
Distributor
Pharmacy
Secured Queue
System
Supply
Information
Queue
Worker
Queue
Worker
Queue
Worker
Monitoring User
Interface
Access
Worker
FDA Inspection
Team
Inspection
Information

Our Roadmap
Build uncoupled microservices
Use Open APIs
De-silo Data
Consider on-chain vs. off
DevOps through Cloud OS
Use Open Source
Deploy using containers
Start with private DLT POC
Public DLT through Hedera
Think value creation
Think edge computing

Questions?
Jim Nasr | @jnasr 
jim.nasr@synchrogenix.com

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Tracking Drug Shortages with Open APIs and Hedera Hashgraph | Hedera18

1. JimNasr VP of Tech & Innovation

2. Tracking Drug Shortage With Open APIs & Hedera Hashgraph Jim Nasr | @jnasr jim.nasr@synchrogenix.com   10.17.18

3. “A hungry tapeworm on the American economy” Warren Buffet on US healthcare systems - January, 2018

5. Moore’s Law vs. Eroom’s Law Moore’s Law: Computing power becomes faster and less expensive over time Eroom’s Law: https://en.wikipedia.org/wiki/Eroom%27s_law Eroom’s Law: Drug discovery is becoming slower and more expensive over time Opportunity   Mobile  IoT  Wearables  Machine Learning

6. DNA of Public DLT Technology Value Creation Culture

7. So, How Does Hedera Help? Near Real-time Transaction Transparency Global Scale Highest Security & Cryptographic Trust Fastest Proof of State Most Efficient Consensus Native Cryptocurrency (Tokenization) Development Flexibility

8. Emergency Response Aid Management Cash Management in Crisis Relief Public Health Data Surveillance Dangerous Substance Tracking Death Certificate Exchange Opioid Tracking Population Health Management Public Health Communication Inventory Tracking Inter-agency data exchange Counterfeit Drug Tracking Clinical Research Collaboration Generic Drug Shortage … Health and Public Cause Use Cases

9. Muhammad Ali “It isn’t the mountains ahead to climb that wear you out; it’s the pebble in your shoe”

10. Getting to World Data

11. Data Insight Continuum

12. Use animation to show immediate app responsiveness Swipe instead of tap The finger is not accurate...size tap targets appropriately! Land Grab for Data Data as currency Legacy data largely siloed and non-interoperable Open technology: “pipes” to connect data sources

13. March 5, 2018

14. Software as a Theme Park http://bit.ly/SWThemePark

15. Constructing the Theme Park… Functional Layer Blueprint Layer DevOps Layer

16. Software Functions as Open APIs Microservices (atomic to multifunctional)

17. Building Software with Open APIs Data Conversion API CDISC Spec Lookup API Basic Reporting API Data Visualization API Process Monitoring API PhUSE Spec Lookup API DS Anonymization API Scorecard API Advanced Reporting API OP React UI Components

18. Relevant Open Technologies… Early Preview: www.OpenPharma.io

19. Generic Drug Supply Shortage POC Active Pharmaceutical Ingredient (API) Manufacturer Factory A Factory B Hedera Network Each API manufacturer can be declared on the network. Each API manufacturer can declare a list of factories and their status (active or not). Each factory needs to declare as well their manufactured ingredients. Distributor Each distributor can be declared on the network and defined their stock availability on ingredients. Pharmacy Each pharmacy can be declared on the network and defined their stock availability on ingredients. Group Purchasing Organization FDA inspectors can publish their inspection reports on factory to the network to identify potential inactivity of some factories. FDA Inspection Team FDA Regulator Team FDA regulators can access data real time on stock availability, factories status, inspection reports through a reporting system to make decision.

20. Application Architecture Manufacturer GPO Distributor Pharmacy Secured Queue System Supply Information Queue Worker Queue Worker Queue Worker Monitoring User Interface Access Worker FDA Inspection Team Inspection Information

21. Generic Drug Supply Shortage Demo

22. Our Roadmap Build uncoupled microservices Use Open APIs De-silo Data Consider on-chain vs. off DevOps through Cloud OS Use Open Source Deploy using containers Start with private DLT POC Public DLT through Hedera Think value creation Think edge computing

23. Questions? Jim Nasr | @jnasr  jim.nasr@synchrogenix.com  

Tracking Drug Shortages with Open APIs and Hedera Hashgraph | Hedera18

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