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What are the Essential Design Features of Personal
Health Records to improve medication adherence:
A literature review
Elisavet Andrikopoulou
PhD Student 1st
year
University of Portsmouth
Centre for Healthcare Modelling & Informatics
Supervisor: Dr Philip Scott
elisavet.andrikopoulou@port.ac.uk
http://www.prayance.co.uk
@Prayance
London Hopper Colloquium 2017
Research Spotlight Competition
Problem and Objectives
Background
• How can personal health records (PHRs) assist adults with long term conditions
improve their medication adherence? What do we know so far?
• How can we:
1. …optimise the PHR technology to fit patient personalities and improve
medication adherence?
2. …use wearable technologies with PHRs to assist medication adherence?
3. …make PHRs more usable for adults with long term conditions?
London Hopper Colloquium 2017
Research Spotlight Competition
Medication
adherence: “the
extent to which a
person’s behaviour
towards their
treatment, agrees with
suggestions from a
clinician”
Polypharmacy: “the
prescribing of multiple
(more than 10) items
of medication to one
individual”
“50% of PHR providers
do not have any
medication adherence
functionality
embedded in their
systems”
Methodology: Inclusion/Exclusion criteria and PICO model
London Hopper Colloquium 2017
Research Spotlight Competition
  Inclusion criteria Exclusion criteria
Participants
• Humans
• 18 years or older suffering from diabetes type 1
and self-administering insulin
• adults suffering from at least one chronic
condition and polypharmacy
• Patients that can self-administer their
medication
• Patients treated outside the hospital only
• Animals
• Pregnant, mentally ill, cancer or terminally ill patients
• adults with multiple chronic conditions but not
polypharmacy or with polypharmacy, but not chronic
conditions
• Patients that require assistance with their medication
• Inpatients only or patients living in care homes
Intervention
Interventions of any type, intensity and frequency,
that aim to investigate the effect of electronic PHRs
in medication adherence, concordance, compliance
or persistence.
Interventions that focus solely on one condition not
investigating comorbidity.
Comparators N/A N/A
Outcome
Any outcome related to the effect of electronic
PHRs in medication adherence, concordance,
compliance or persistence.
N/A
Study 
design/type
Published studies from 2012 to 2017, without any
geographical restriction.
Abstract-only reports without any references, commercial
studies, party political statements, review papers,
magazine or newspaper articles, withdrawn abstracts or
articles, protocols of reviews.
Table 1: Summary of the PICOS elements included and excluded in the systematic literature review
Quality assessment, data analysis & search strategy
Future Work
a) b)
• Cochrane GRADE system and the CASP
checklists will be combined for quality
assessment and risk of bias analysis.
• The databases searches include keywords
such as PHR, polypharmacy, adults,
chronic condition and medication
adherence.
• Narrative synthesis of known ways that
the PHR are used to assist chronically ill
patients with medication adherence.
This literature review will provide a reference background in evaluation of the
electronic PHR, to support medicines optimisation and improving shared
understanding for patients and practitioners.
Figure 1: PRISMA Flow Diagram (still in progress)
London Hopper Colloquium 2017
Research Spotlight Competition

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What are the essential design features of personal health records to improve medication adherence: A literature review

  • 1. What are the Essential Design Features of Personal Health Records to improve medication adherence: A literature review Elisavet Andrikopoulou PhD Student 1st year University of Portsmouth Centre for Healthcare Modelling & Informatics Supervisor: Dr Philip Scott elisavet.andrikopoulou@port.ac.uk http://www.prayance.co.uk @Prayance London Hopper Colloquium 2017 Research Spotlight Competition
  • 2. Problem and Objectives Background • How can personal health records (PHRs) assist adults with long term conditions improve their medication adherence? What do we know so far? • How can we: 1. …optimise the PHR technology to fit patient personalities and improve medication adherence? 2. …use wearable technologies with PHRs to assist medication adherence? 3. …make PHRs more usable for adults with long term conditions? London Hopper Colloquium 2017 Research Spotlight Competition Medication adherence: “the extent to which a person’s behaviour towards their treatment, agrees with suggestions from a clinician” Polypharmacy: “the prescribing of multiple (more than 10) items of medication to one individual” “50% of PHR providers do not have any medication adherence functionality embedded in their systems”
  • 3. Methodology: Inclusion/Exclusion criteria and PICO model London Hopper Colloquium 2017 Research Spotlight Competition   Inclusion criteria Exclusion criteria Participants • Humans • 18 years or older suffering from diabetes type 1 and self-administering insulin • adults suffering from at least one chronic condition and polypharmacy • Patients that can self-administer their medication • Patients treated outside the hospital only • Animals • Pregnant, mentally ill, cancer or terminally ill patients • adults with multiple chronic conditions but not polypharmacy or with polypharmacy, but not chronic conditions • Patients that require assistance with their medication • Inpatients only or patients living in care homes Intervention Interventions of any type, intensity and frequency, that aim to investigate the effect of electronic PHRs in medication adherence, concordance, compliance or persistence. Interventions that focus solely on one condition not investigating comorbidity. Comparators N/A N/A Outcome Any outcome related to the effect of electronic PHRs in medication adherence, concordance, compliance or persistence. N/A Study  design/type Published studies from 2012 to 2017, without any geographical restriction. Abstract-only reports without any references, commercial studies, party political statements, review papers, magazine or newspaper articles, withdrawn abstracts or articles, protocols of reviews. Table 1: Summary of the PICOS elements included and excluded in the systematic literature review
  • 4. Quality assessment, data analysis & search strategy Future Work a) b) • Cochrane GRADE system and the CASP checklists will be combined for quality assessment and risk of bias analysis. • The databases searches include keywords such as PHR, polypharmacy, adults, chronic condition and medication adherence. • Narrative synthesis of known ways that the PHR are used to assist chronically ill patients with medication adherence. This literature review will provide a reference background in evaluation of the electronic PHR, to support medicines optimisation and improving shared understanding for patients and practitioners. Figure 1: PRISMA Flow Diagram (still in progress) London Hopper Colloquium 2017 Research Spotlight Competition