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CERVICAL CANCER
DR. SRABANA MISRA BHAGABATY, MD
ASSISSTANT PROFESSOR,
DEPARTMENT OF PREVENTIVE ONCOLOGY
DR. B.BOROOAH CANCER INSTITUTE
Om , sarve bhavantu sukhina
sarve santu niramaya
sarve bhadrani pasyantu
ma kashchi dukha bhagbhavet
om shanti, santi santi
CANCER
CANCER OCCURS WHEN CELLS IN A
PART OF THE BODY BEGIN TO GROW
OUT OF CONTROL.
NORMAL CELLS DIVIDE AND GROW IN
AN ORDERLY FASHION, BUT CANCER
CELLS DO NOT.
THEY CONTINUE TO GROW AND
CROWD OUT NORMAL CELLS. THIS
OUT OF CONTROL GROWTH IS THE
HALLMARK OF CANCER.
CERVIX: THE LOWERMOST PART OF WOMB (UTERUS). IT IS THE OPENING OF
THE UTERUS INTO THE VAGINA
FELLOPIAN TUBES
OVERIES
UTERUS
CERVIXVAGINA
SRABANA
GLOBOCON 2012:
CERVICAL CANCER
INCIDENCE
SRABANA
GLOBOCON 2012:
CERVICAL CANCER
MORTALITY
SRABANA
GLOBALLY
5 LAKH 28 THOUSANDS NEW CASES
2 LAKH 66 THOUSANDS DEATH
INDIAN SCENERIO
1 LAKH 23 THOUSANDS NEW CASES
67 THOUSANDS DEATH
SRABANA
SRABANA
PBCR-2009-11
WHAT CAUSES CERVICAL CANCER ?
SRABANA
• The central cause of cervical cancer is human
papillomavirus ( HPV )
ROUTES OF INFECTION
> HPV is transmitted through sexual contact with HPV
infected partner
HOW COMMONE IS THIS EXPOSURE
> More than 75% of sexually active women have been
exposed to HPV by age 18-22 years
If someone gets HPV infection, does it mean
she will definitely get cervical cancer?
Not always!
In most cases HPV infection will go away
Only women with persistent HPV (where the
virus does not go away) are at risk for cervical
cancer
NATURAL HISTORY OF CERVICAL CANCER
HPV
Infecti
on
dysplasi
a
High
grade
dysplasia
Invasive
cancer
- 70%
-15% -15% in 2 years
- 33% in 10 years
SRABANA
Other risk factors of cervical cancer
 EARLY MARRIAGE
 YOUNG AGE AT FIRST PREGNANCY
 SHORT INTEVAL BETWEEN PREGNANCY
 POOR NUTRITION
 POOR GENITAL HYGEINE
 WOMEN WITH STD
 WOMEN WITH MULTIPLE SEXUAL PARTNER
 HUSBAND WITH MULTIPLE SEXUAL PARTNER
 SMOKING
SRABANA
PREVENTION AND
EARLY DETECTION
CAN SAVE LIVES
PREVENTION :
By lowering risk
 Delay onset of sexual activity
 AVOID TOBACCO
 Maintaining a healthy diet and lifestyle
 Practicing safe sex. Condoms decrease the chance of
HPV exposure.
 If eligible, getting the vaccine that prevents most
cervical cancers.
 Getting Pap test and HPV testing as recommended by
health care provider.
SRABANA
:HPV VACCINATION :
It is recommended that girls
receive the vaccine prior to
becoming sexually active.
There are two HPV vaccines
(Gardasil and Cervarix) which
reduce the risk of cancerous or
precancerous changes of the
cervix and perineum by about
93% and 62%, respectively
SRABANA
Gardasil(types 6, 11, 16, 18) is given in three injections over six
months. The second injection is two months after the first, and
the third injection is six months after the first shot was
administered.
Immunization with Cervarix (type 16 and 18)consists of 3 doses
of 0.5-mL each, by intramuscular injection according to the
following schedule: 0, 1, and 6 months. The preferred site of
administration is the deltoid region of the upper arm
SRABANA
CERVICAL CANCER – IDEAL FOR SCREENING
• CERVIX EASILY ACCESSIBLE FOR
EXAMINATION
• LONG LATENT PRECANCEROUS PHASE
SRABANA
TESTS FOR EARLY DETECTION
• VIA- VISUAL INSPECTION UNDER ACETIC ACID
• VILI-VISUAL INSPECTION UNDER LUGOLS
IODINE
• PAP TEST
SRABANA
What is a Pap test?
 A test which collects cells from the surface of the cervix and
looks for any abnormal cells
 Abnormal cells can be treated before cervical cancer
develops
 When cancer is detected early, it is easier
to treat
SRABANA
WHO RECOMMENDATION FOR
DEVELOPING COUNTRIES
IDEAL
3 YEARLY 20 – 65 YEARS
5 – 10 YEARS INTERVAL AGE GROUP 35 – 65
YRS.
IF RESOURCES LIMITED
A SINGLE APPROPRIATELY TIMED SMEAR
PREFERRABLY AROUND 40 YEARS FOR
MAXIMUM EFFECT
SRABANA
CANCER CERVIX – REASONS
FOR LATE DIAGNOSIS
FEAR
IGNORANCE
EMBARRASSEMENT
PAINLESS SYMPTOM COMPLEX
SRABANA
SYMPTOMS
• ASYMPTOMATIC IN EARLY STAGES
• BLEEDING
- POST COITAL
- INTERMENSTRUAL
- POST MENOPAUSAL
• VAGINAL DISCHARGE
• PAIN
• RECTAL / URINARY SYMPTOM
• SEVER WEIGHT LOSS/ WEAKNESS
SRABANA
MAIN MODALITIES OFTREATMENT
• SURGERY
• CHEMOTHERAPY
• RADIOTHERAPY
CONCLUSION
 ONE OF THE COMMONEST CAUSE OF CANCER
RELATED DEATHS IN INDIA
 IT IS A PREVENTABLE DISEASE
 EARLY DETECTION IS POSSIBLE BY SCREENING
 PROPERLY TIMED PAP SMEAR ADDS TO THE POOL OF
EARLY DETECTION AND TREATMENT
 PUBLIC EDUCATION AND REMOVING TABOOS AND
MISCONCEPTIONS BEING PARAMOUNT IMPORTANCE
IN TOTAL CONTROL OF THE DISEASE
SRABANA
KV Khanapara organized by State
Tobacco Control / District Tobacco
Control Cell : Dated 25.082014. Total
participants: 1500
Cotton Collegiate H.S School organized by
State Tobacco Control / District Tobacco
Control Cell : Dated 26.08.2014. Total
participants: 250
Teachers sensitization and interective session : by Preventive
Oncology BBCI Cotton Collegiate H.S School: 11.09.2014. total
participants : 28
Teacher (college) student sensitization : by Preventive Oncology BBCI : National Education
Foundation of management and technology : 16.09.2014: participants: teachers: 29,
students: 170
Drug deaddiction centres:
Serenity foundation: 22.08.2014
Kripa foundation 29.08.2014
Rally 4th september 2014
Street play : tobacco and cancer : concept, script writing , directed
by Preventive Oncology,bbci: acting by staff of BBCI: 4th September
2014
CANCER AWARENESS ALONG WITH CERVICAL BREAST AND HEAD AND NECK
CANCER SCREENING CAMP: 4.11.2014: RANI COMMUNITY DEVELOPMENT
BLOCK
THANK YOU
SRABANASRABANA

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Cervical cancer

  • 1. CERVICAL CANCER DR. SRABANA MISRA BHAGABATY, MD ASSISSTANT PROFESSOR, DEPARTMENT OF PREVENTIVE ONCOLOGY DR. B.BOROOAH CANCER INSTITUTE
  • 2. Om , sarve bhavantu sukhina sarve santu niramaya sarve bhadrani pasyantu ma kashchi dukha bhagbhavet om shanti, santi santi
  • 3. CANCER CANCER OCCURS WHEN CELLS IN A PART OF THE BODY BEGIN TO GROW OUT OF CONTROL. NORMAL CELLS DIVIDE AND GROW IN AN ORDERLY FASHION, BUT CANCER CELLS DO NOT. THEY CONTINUE TO GROW AND CROWD OUT NORMAL CELLS. THIS OUT OF CONTROL GROWTH IS THE HALLMARK OF CANCER.
  • 4. CERVIX: THE LOWERMOST PART OF WOMB (UTERUS). IT IS THE OPENING OF THE UTERUS INTO THE VAGINA FELLOPIAN TUBES OVERIES UTERUS CERVIXVAGINA SRABANA
  • 7. GLOBALLY 5 LAKH 28 THOUSANDS NEW CASES 2 LAKH 66 THOUSANDS DEATH INDIAN SCENERIO 1 LAKH 23 THOUSANDS NEW CASES 67 THOUSANDS DEATH SRABANA
  • 8.
  • 10. WHAT CAUSES CERVICAL CANCER ? SRABANA • The central cause of cervical cancer is human papillomavirus ( HPV ) ROUTES OF INFECTION > HPV is transmitted through sexual contact with HPV infected partner HOW COMMONE IS THIS EXPOSURE > More than 75% of sexually active women have been exposed to HPV by age 18-22 years
  • 11. If someone gets HPV infection, does it mean she will definitely get cervical cancer? Not always! In most cases HPV infection will go away Only women with persistent HPV (where the virus does not go away) are at risk for cervical cancer
  • 12. NATURAL HISTORY OF CERVICAL CANCER HPV Infecti on dysplasi a High grade dysplasia Invasive cancer - 70% -15% -15% in 2 years - 33% in 10 years SRABANA
  • 13. Other risk factors of cervical cancer  EARLY MARRIAGE  YOUNG AGE AT FIRST PREGNANCY  SHORT INTEVAL BETWEEN PREGNANCY  POOR NUTRITION  POOR GENITAL HYGEINE  WOMEN WITH STD  WOMEN WITH MULTIPLE SEXUAL PARTNER  HUSBAND WITH MULTIPLE SEXUAL PARTNER  SMOKING SRABANA
  • 15. PREVENTION : By lowering risk  Delay onset of sexual activity  AVOID TOBACCO  Maintaining a healthy diet and lifestyle  Practicing safe sex. Condoms decrease the chance of HPV exposure.  If eligible, getting the vaccine that prevents most cervical cancers.  Getting Pap test and HPV testing as recommended by health care provider. SRABANA
  • 16. :HPV VACCINATION : It is recommended that girls receive the vaccine prior to becoming sexually active. There are two HPV vaccines (Gardasil and Cervarix) which reduce the risk of cancerous or precancerous changes of the cervix and perineum by about 93% and 62%, respectively SRABANA
  • 17. Gardasil(types 6, 11, 16, 18) is given in three injections over six months. The second injection is two months after the first, and the third injection is six months after the first shot was administered. Immunization with Cervarix (type 16 and 18)consists of 3 doses of 0.5-mL each, by intramuscular injection according to the following schedule: 0, 1, and 6 months. The preferred site of administration is the deltoid region of the upper arm SRABANA
  • 18. CERVICAL CANCER – IDEAL FOR SCREENING • CERVIX EASILY ACCESSIBLE FOR EXAMINATION • LONG LATENT PRECANCEROUS PHASE SRABANA
  • 19. TESTS FOR EARLY DETECTION • VIA- VISUAL INSPECTION UNDER ACETIC ACID • VILI-VISUAL INSPECTION UNDER LUGOLS IODINE • PAP TEST SRABANA
  • 20. What is a Pap test?  A test which collects cells from the surface of the cervix and looks for any abnormal cells  Abnormal cells can be treated before cervical cancer develops  When cancer is detected early, it is easier to treat SRABANA
  • 21. WHO RECOMMENDATION FOR DEVELOPING COUNTRIES IDEAL 3 YEARLY 20 – 65 YEARS 5 – 10 YEARS INTERVAL AGE GROUP 35 – 65 YRS. IF RESOURCES LIMITED A SINGLE APPROPRIATELY TIMED SMEAR PREFERRABLY AROUND 40 YEARS FOR MAXIMUM EFFECT SRABANA
  • 22. CANCER CERVIX – REASONS FOR LATE DIAGNOSIS FEAR IGNORANCE EMBARRASSEMENT PAINLESS SYMPTOM COMPLEX SRABANA
  • 23. SYMPTOMS • ASYMPTOMATIC IN EARLY STAGES • BLEEDING - POST COITAL - INTERMENSTRUAL - POST MENOPAUSAL • VAGINAL DISCHARGE • PAIN • RECTAL / URINARY SYMPTOM • SEVER WEIGHT LOSS/ WEAKNESS SRABANA
  • 24. MAIN MODALITIES OFTREATMENT • SURGERY • CHEMOTHERAPY • RADIOTHERAPY
  • 25. CONCLUSION  ONE OF THE COMMONEST CAUSE OF CANCER RELATED DEATHS IN INDIA  IT IS A PREVENTABLE DISEASE  EARLY DETECTION IS POSSIBLE BY SCREENING  PROPERLY TIMED PAP SMEAR ADDS TO THE POOL OF EARLY DETECTION AND TREATMENT  PUBLIC EDUCATION AND REMOVING TABOOS AND MISCONCEPTIONS BEING PARAMOUNT IMPORTANCE IN TOTAL CONTROL OF THE DISEASE SRABANA
  • 26. KV Khanapara organized by State Tobacco Control / District Tobacco Control Cell : Dated 25.082014. Total participants: 1500
  • 27.
  • 28. Cotton Collegiate H.S School organized by State Tobacco Control / District Tobacco Control Cell : Dated 26.08.2014. Total participants: 250
  • 29. Teachers sensitization and interective session : by Preventive Oncology BBCI Cotton Collegiate H.S School: 11.09.2014. total participants : 28
  • 30. Teacher (college) student sensitization : by Preventive Oncology BBCI : National Education Foundation of management and technology : 16.09.2014: participants: teachers: 29, students: 170
  • 31. Drug deaddiction centres: Serenity foundation: 22.08.2014 Kripa foundation 29.08.2014
  • 33. Street play : tobacco and cancer : concept, script writing , directed by Preventive Oncology,bbci: acting by staff of BBCI: 4th September 2014
  • 34. CANCER AWARENESS ALONG WITH CERVICAL BREAST AND HEAD AND NECK CANCER SCREENING CAMP: 4.11.2014: RANI COMMUNITY DEVELOPMENT BLOCK