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29/08/12	
  




       Graded	
  ac.vity	
  and	
  exposure	
  

                  Jon	
  Ford	
  (PhD,	
  Mphysio,	
  
                 BappScPhysio,	
  Cred	
  MDT)	
  




                          Preamble	
  
•    Principles	
  already	
  introduced	
  
•    Frequency	
  of	
  use	
  
•    Review	
  and	
  prac.cal	
  session	
  
•    Implica.ons	
  for	
  future	
  RCTs	
  
     –  Treatment	
  protocol	
  
     –  Study	
  physios	
  
•  Implica.ons	
  for	
  career	
  paths	
  (eg	
  pain	
  
   management)	
  




                                                                       1	
  
29/08/12	
  




                           Today’s	
  session	
  
•      Review	
  of	
  nomenclature	
  and	
  mechanisms	
  
•      Review	
  of	
  treatment	
  components	
  
•      Review	
  of	
  SMC	
  process	
  
•      Prac.cal	
  implementa.on	
  




                                  Defini.ons	
  
•  Anxiety	
  
       –  Displeasing	
  feeling	
  of	
  fear	
  and	
  concern	
  
       –  Adap.ve	
  -­‐	
  helps	
  an	
  individual	
  to	
  deal	
  with	
  a	
  
          stressor	
  by	
  promp.ng	
  them	
  to	
  cope	
  with	
  it	
  
       –  Maladap.ve	
  -­‐	
  when	
  overwhelming	
  and	
  
          dispropor.onate	
  to	
  stressor	
  
	
  




                                                                                                2	
  
29/08/12	
  




                     Types	
  of	
  anxiety	
  
•  Related	
  to	
  pain	
  and	
  perceived	
  threats	
  
   associated	
  with	
  pain	
  
•  Generalised	
  anxiety	
  not	
  related	
  to	
  pain	
  
•  Post	
  trauma.c	
  stress	
  disorder	
  




•  Pain-­‐related	
  fear	
  and	
  anxiety	
  	
  
    –  When	
  s.muli	
  that	
  are	
  related	
  to	
  pain	
  are	
  
       perceived	
  as	
  a	
  main	
  threat	
  
    –  Results	
  in	
  psychophysiological	
  (eg	
  heightened	
  
       muscle	
  reac.vity),	
  behavioral	
  (eg	
  escape	
  and	
  
       avoidance	
  behavior),	
  as	
  well	
  as	
  cogni.ve	
  (eg	
  
       catastrophising	
  thoughts)	
  elements	
  




                                                                                     3	
  
29/08/12	
  




                       Catastrophising	
  
•  Anxious	
  pa.ents	
  dwell	
  on	
  the	
  most	
  extreme	
  
     nega.ve	
  consequences	
  conceivable	
  
•  The	
  cogni.ve	
  element	
  of	
  fear/anxiety	
  	
  
•  Pain	
  is	
  interpreted	
  as	
  being	
  extremely	
  
     threatening	
  
	
  
      (Crombez	
  et	
  al.,	
  1998;	
  Rosens.el	
  and	
  Keefe,	
  1983)	
  




                        Hypervigilance	
  
   –  Environmental	
  scanning	
  for	
  poten.al	
  sources	
  of	
  
      threat,	
  selec.vely	
  aending	
  to	
  threat	
  related	
  
      rather	
  than	
  neutral	
  s.muli,	
  broadening	
  of	
  the	
  
      aen.on	
  prior	
  to	
  the	
  detec.on	
  of	
  these	
  s.muli,	
  
      and	
  narrows	
  the	
  aen.on	
  in	
  the	
  presence	
  of	
  such	
  
      s.muli	
  (Eysenck,	
  1992)	
  
   –  Both	
  avoidance	
  behavior	
  and	
  hypervigilance	
  
      reduce	
  anxiety	
  in	
  the	
  short	
  term,	
  but	
  may	
  be	
  
      counterproduc.ve	
  in	
  the	
  long	
  run.	
  




                                                                                             4	
  
29/08/12	
  




                                Avoidance	
  
   •  Behavior	
  aimed	
  at	
  postponing	
  or	
  preven.ng	
  
      an	
  aversive	
  	
  
   •  In	
  chronic	
  pain	
  it	
  is	
  not	
  possible	
  to	
  avoid	
  the	
  
      pain	
  
   •  Is	
  possible	
  to	
  avoid	
  the	
  perceived	
  threat	
  (eg	
  
      ac.vi.es	
  that	
  are	
  assumed	
  to	
  increase	
  pain	
  or	
  
      (re)injury)	
  




Leeuw	
  et	
  al	
  2007	
  




                                                                                                5	
  
29/08/12	
  




                           Modern	
  defini.on	
  
•  Fear/anxiety	
  on	
  the	
  affec.ve	
  level	
  
•  Associated	
  with	
  automa.c	
  thoughts	
  (eg	
  
   catastrophizing)	
  or	
  more	
  generalized	
  
   appraisals	
  (eg	
  fear-­‐avoidance	
  beliefs)	
  on	
  the	
  
   cogni.ve	
  level	
  
•  Leads	
  to	
  avoidance	
  of	
  pain	
  associated	
  
   ac.vi.es	
  on	
  the	
  behavioural	
  level	
  and	
  disuse	
  

   	
   	
   	
   	
  (Hasenbring	
  and	
  Verbunt	
  2010)	
  




                    Disuse/decondi.oning	
  
•  Conflic.ng	
  evidence	
  suppor.ng	
  different	
  
   levels	
  of	
  decondi.oning	
  between	
  people	
  with	
  
   CLBD	
  and	
  matched	
  controls	
  	
  (Smeets	
  al.	
  2006;	
  
   Verbunt	
  et	
  al.	
  2010)	
  	
  	
  
•  Measurement	
  issues	
  	
  
    –  Pa.ents’	
  performance	
  may	
  be	
  influenced	
  by	
  pain	
  
       inhibi.on	
  (Leeuw,	
  Goossens	
  et	
  al.	
  2007)	
  




                                                                                      6	
  
29/08/12	
  




                  Evidence	
  of	
  causa.on	
  
•  Cross	
  sec.onal	
  studies	
  
    –  Associa.on	
  between	
  causal	
  components	
  of	
  the	
  fear	
  
       avoidance	
  model	
  as	
  well	
  as	
  with	
  other	
  measures	
  of	
  
       CLBD	
  such	
  as	
  pain	
  and	
  disability	
  (Leeuw	
  et	
  al.	
  2007;	
  
       Wideman	
  et	
  al	
  2009;	
  Pincus	
  et	
  al.	
  2010)	
  	
  	
  
•  Conflic.ng	
  evidence	
  on	
  cause/effect	
  rela.onships	
  	
  
   (Pincus,	
  Vogel	
  et	
  al.	
  2006;	
  Pincus,	
  Smeets	
  et	
  al.	
  2010)	
  
•  Recent	
  study	
  shows	
  that	
  although	
  
   catastrophising	
  and	
  FA	
  predict	
  poor	
  RTW	
  
   independently,	
  catastrophising	
  does	
  not	
  predict	
  
   development	
  of	
  FA	
  (Wideman	
  et	
  al.	
  2009)	
  




                                  Conclusion	
  
The	
  research	
  to	
  date	
  on	
  fear	
  avoidance	
  is	
  conflic.ng	
  
likely	
  resul.ng	
  from	
  the	
  model	
  being	
  overly	
  simplis.c…	
  	
  
	
  
Whilst	
  each	
  individual	
  component	
  of	
  the	
  fear	
  avoidance	
  
model	
  appears	
  to	
  be	
  important	
  in	
  presenta.on	
  and	
  
prognosis,	
  the	
  causal	
  rela.onship	
  between	
  these	
  
components	
  is	
  unclear	
  
	
  
    (Pincus,	
  Vogel	
  et	
  al.	
  2006;	
  Leeuw,	
  Goossens	
  et	
  al.	
  2007;	
  
    Hasenbring	
  and	
  Verbunt	
  2010;	
  Pincus,	
  Smeets	
  et	
  al.	
  2010;	
  
    Simmonds,	
  Smeets	
  et	
  al.	
  2010)	
  




                                                                                                       7	
  
29/08/12	
  




             Treatment	
  implica.ons	
  
•  Target	
  catastrophising,	
  fear/anxiety,	
  
   avoidance	
  behaviour,	
  disuse?	
  




                        Other	
  factors	
  
•  Other	
  factors	
  worthy	
  of	
  considera.on?	
  
    –  Mo.va.on,	
  emo.onal	
  state,	
  level	
  of	
  pain,	
  self-­‐
       efficacy,	
  and	
  physical	
  decondi.oning	
  
•  Psychosocial	
  factors	
  generally	
  predict	
  less	
  
   than	
  30%	
  of	
  the	
  variance	
  in	
  outcome	
  when	
  
   examined	
  as	
  a	
  predictor	
  
    –  Pathology	
  




                                                                                     8	
  
29/08/12	
  




                          Graded	
  ac.vity	
  
•  Based	
  on	
  operant	
  condi.oning	
  principles	
  for	
  chronic	
  
   pain	
  (Fordyce,	
  Fowler	
  et	
  al.	
  1973)	
  
•  Posi.ve	
  reinforcement	
  of	
  healthy	
  behaviors/not	
  
   reinforcing	
  illness	
  behaviours	
  
•  Iden.fy	
  func.onal	
  goals	
  
•  Establish	
  baseline	
  	
  
•  Commence	
  ac.vity	
  below	
  baseline	
  levels	
  
•  Incremental	
  increase	
  in	
  ac.vi.es	
  in	
  a	
  .me	
  con.ngent	
  
   manner	
  regardless	
  of	
  pain	
  
     	
  
            Macedo	
  et	
  al	
  2010	
  




                       Graded	
  exposure	
  
•  Feared	
  ac.vity	
  iden.fied	
  
•  A	
  hierarchy	
  of	
  feared	
  ac.vi.es	
  created	
  
•  Exposure	
  started	
  with	
  the	
  least	
  feared	
  ac.vity	
  
•  Assist	
  the	
  pa.ent	
  in	
  appraising	
  the	
  exposure	
  to	
  
   feared	
  ac.vi.es	
  and	
  its	
  consequences	
  
•  Address	
  irra.onal	
  beliefs	
  and/or	
  
   counterproduc.ve	
  beliefs	
  

            Macedo	
  et	
  al	
  2010	
  




                                                                                           9	
  
29/08/12	
  




                  Similari.es	
  and	
  differences?	
  
   •  Both	
  challenge	
  counter-­‐produc.ve	
  cogni.ons	
  
   •  Graded	
  exposure	
  	
  
           –  Generalises	
  to	
  a	
  variety	
  of	
  fears	
  
           –  More	
  direct	
  in	
  addressing	
  beliefs	
  
           –  Oken	
  performed	
  by	
  psychologists	
  




George	
  et	
  al	
  2004	
  




                                                                             10	
  
29/08/12	
  




                                        Case	
  study	
  
•  Pa.ent	
  profile	
  
      –  40	
  year	
  old	
  storeman	
  with	
  5	
  and	
  8	
  year	
  old	
  
      –  FABQ	
  50/60	
  
      –  Oswesty	
  60%	
  
             •  Walking	
  limited	
  to	
  500m	
  
             •  Simng	
  limited	
  to	
  10	
  min	
  
             •  Can	
  only	
  lik	
  very	
  light	
  weights	
  
•  How	
  would	
  you	
  establish	
  func.onal	
  goals?	
  
•  What	
  would	
  your	
  baseline	
  home	
  program	
  be?	
  
•  What	
  methods	
  of	
  reinforcement	
  would	
  you	
  use?	
  




George	
  and	
  Zeppieri	
  2009	
  




                                                                                             11	
  
29/08/12	
  




                  Review	
  of	
  PHODA	
  
•  40	
  pictures	
  where	
  pa.ent	
  can	
  rate	
  their	
  level	
  
   of	
  fear	
  
•  PC	
  only	
  
•  hp://www.psychology.unimaas.nl/phoda-­‐
   sev/Phoda-­‐SeV_UK.htm	
  




                                                                                    12	
  
29/08/12	
  




                             Case	
  study	
  
•  25	
  year	
  old	
  FT	
  marke.ng	
  student	
  
    –  Referred	
  by	
  Metro	
  Spinal	
  
    –  DASS	
  –	
  moderate	
  depression	
  and	
  anxiety	
  
    –  Marked	
  maladap.ve	
  cure	
  focus	
  
    –  Unable	
  to	
  return	
  play	
  netball	
  
•  What	
  interven.on	
  (psych	
  FC)	
  
•  Role	
  play	
  session	
  1	
  explana.on	
  
•  Swap	
  and	
  role	
  play	
  overcoming	
  an	
  increase	
  in	
  
   pain	
  




                             Case	
  study	
  
•  50	
  year	
  old	
  home	
  mum	
  with	
  adult	
  children	
  
    –  TAC	
  with	
  moderate	
  PTSD	
  
    –  Concurrent	
  moderate	
  severity	
  chronic	
  pain	
  problem	
  
    –  Socially	
  isolated	
  and	
  cannot	
  drive	
  
    –  Psychology	
  has	
  not	
  helped	
  
    –  10	
  sessions	
  physio	
  before	
  termina.on	
  of	
  all	
  medical	
  
       and	
  like	
  
•  What	
  interven.on?	
  
•  Role	
  play	
  iden.fica.on	
  of	
  hierarchical	
  list	
  fears	
  
•  Plan	
  an	
  an.cipated	
  progression	
  of	
  ac.vity/
   situa.on	
  over	
  10	
  sessions	
  




                                                                                              13	
  
29/08/12	
  




Contact	
  
E: 	
   	
  stopsbackpain@gmail.com	
  
W:	
  	
   	
  www.facebook.com/STOPSbackpain	
  
T: 	
   	
  @stopsbackpain	
  




                                                            14	
  

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STOPS Back Pain - Graded Activity and Exposure

  • 1. 29/08/12   Graded  ac.vity  and  exposure   Jon  Ford  (PhD,  Mphysio,   BappScPhysio,  Cred  MDT)   Preamble   •  Principles  already  introduced   •  Frequency  of  use   •  Review  and  prac.cal  session   •  Implica.ons  for  future  RCTs   –  Treatment  protocol   –  Study  physios   •  Implica.ons  for  career  paths  (eg  pain   management)   1  
  • 2. 29/08/12   Today’s  session   •  Review  of  nomenclature  and  mechanisms   •  Review  of  treatment  components   •  Review  of  SMC  process   •  Prac.cal  implementa.on   Defini.ons   •  Anxiety   –  Displeasing  feeling  of  fear  and  concern   –  Adap.ve  -­‐  helps  an  individual  to  deal  with  a   stressor  by  promp.ng  them  to  cope  with  it   –  Maladap.ve  -­‐  when  overwhelming  and   dispropor.onate  to  stressor     2  
  • 3. 29/08/12   Types  of  anxiety   •  Related  to  pain  and  perceived  threats   associated  with  pain   •  Generalised  anxiety  not  related  to  pain   •  Post  trauma.c  stress  disorder   •  Pain-­‐related  fear  and  anxiety     –  When  s.muli  that  are  related  to  pain  are   perceived  as  a  main  threat   –  Results  in  psychophysiological  (eg  heightened   muscle  reac.vity),  behavioral  (eg  escape  and   avoidance  behavior),  as  well  as  cogni.ve  (eg   catastrophising  thoughts)  elements   3  
  • 4. 29/08/12   Catastrophising   •  Anxious  pa.ents  dwell  on  the  most  extreme   nega.ve  consequences  conceivable   •  The  cogni.ve  element  of  fear/anxiety     •  Pain  is  interpreted  as  being  extremely   threatening     (Crombez  et  al.,  1998;  Rosens.el  and  Keefe,  1983)   Hypervigilance   –  Environmental  scanning  for  poten.al  sources  of   threat,  selec.vely  aending  to  threat  related   rather  than  neutral  s.muli,  broadening  of  the   aen.on  prior  to  the  detec.on  of  these  s.muli,   and  narrows  the  aen.on  in  the  presence  of  such   s.muli  (Eysenck,  1992)   –  Both  avoidance  behavior  and  hypervigilance   reduce  anxiety  in  the  short  term,  but  may  be   counterproduc.ve  in  the  long  run.   4  
  • 5. 29/08/12   Avoidance   •  Behavior  aimed  at  postponing  or  preven.ng   an  aversive     •  In  chronic  pain  it  is  not  possible  to  avoid  the   pain   •  Is  possible  to  avoid  the  perceived  threat  (eg   ac.vi.es  that  are  assumed  to  increase  pain  or   (re)injury)   Leeuw  et  al  2007   5  
  • 6. 29/08/12   Modern  defini.on   •  Fear/anxiety  on  the  affec.ve  level   •  Associated  with  automa.c  thoughts  (eg   catastrophizing)  or  more  generalized   appraisals  (eg  fear-­‐avoidance  beliefs)  on  the   cogni.ve  level   •  Leads  to  avoidance  of  pain  associated   ac.vi.es  on  the  behavioural  level  and  disuse          (Hasenbring  and  Verbunt  2010)   Disuse/decondi.oning   •  Conflic.ng  evidence  suppor.ng  different   levels  of  decondi.oning  between  people  with   CLBD  and  matched  controls    (Smeets  al.  2006;   Verbunt  et  al.  2010)       •  Measurement  issues     –  Pa.ents’  performance  may  be  influenced  by  pain   inhibi.on  (Leeuw,  Goossens  et  al.  2007)   6  
  • 7. 29/08/12   Evidence  of  causa.on   •  Cross  sec.onal  studies   –  Associa.on  between  causal  components  of  the  fear   avoidance  model  as  well  as  with  other  measures  of   CLBD  such  as  pain  and  disability  (Leeuw  et  al.  2007;   Wideman  et  al  2009;  Pincus  et  al.  2010)       •  Conflic.ng  evidence  on  cause/effect  rela.onships     (Pincus,  Vogel  et  al.  2006;  Pincus,  Smeets  et  al.  2010)   •  Recent  study  shows  that  although   catastrophising  and  FA  predict  poor  RTW   independently,  catastrophising  does  not  predict   development  of  FA  (Wideman  et  al.  2009)   Conclusion   The  research  to  date  on  fear  avoidance  is  conflic.ng   likely  resul.ng  from  the  model  being  overly  simplis.c…       Whilst  each  individual  component  of  the  fear  avoidance   model  appears  to  be  important  in  presenta.on  and   prognosis,  the  causal  rela.onship  between  these   components  is  unclear     (Pincus,  Vogel  et  al.  2006;  Leeuw,  Goossens  et  al.  2007;   Hasenbring  and  Verbunt  2010;  Pincus,  Smeets  et  al.  2010;   Simmonds,  Smeets  et  al.  2010)   7  
  • 8. 29/08/12   Treatment  implica.ons   •  Target  catastrophising,  fear/anxiety,   avoidance  behaviour,  disuse?   Other  factors   •  Other  factors  worthy  of  considera.on?   –  Mo.va.on,  emo.onal  state,  level  of  pain,  self-­‐ efficacy,  and  physical  decondi.oning   •  Psychosocial  factors  generally  predict  less   than  30%  of  the  variance  in  outcome  when   examined  as  a  predictor   –  Pathology   8  
  • 9. 29/08/12   Graded  ac.vity   •  Based  on  operant  condi.oning  principles  for  chronic   pain  (Fordyce,  Fowler  et  al.  1973)   •  Posi.ve  reinforcement  of  healthy  behaviors/not   reinforcing  illness  behaviours   •  Iden.fy  func.onal  goals   •  Establish  baseline     •  Commence  ac.vity  below  baseline  levels   •  Incremental  increase  in  ac.vi.es  in  a  .me  con.ngent   manner  regardless  of  pain     Macedo  et  al  2010   Graded  exposure   •  Feared  ac.vity  iden.fied   •  A  hierarchy  of  feared  ac.vi.es  created   •  Exposure  started  with  the  least  feared  ac.vity   •  Assist  the  pa.ent  in  appraising  the  exposure  to   feared  ac.vi.es  and  its  consequences   •  Address  irra.onal  beliefs  and/or   counterproduc.ve  beliefs   Macedo  et  al  2010   9  
  • 10. 29/08/12   Similari.es  and  differences?   •  Both  challenge  counter-­‐produc.ve  cogni.ons   •  Graded  exposure     –  Generalises  to  a  variety  of  fears   –  More  direct  in  addressing  beliefs   –  Oken  performed  by  psychologists   George  et  al  2004   10  
  • 11. 29/08/12   Case  study   •  Pa.ent  profile   –  40  year  old  storeman  with  5  and  8  year  old   –  FABQ  50/60   –  Oswesty  60%   •  Walking  limited  to  500m   •  Simng  limited  to  10  min   •  Can  only  lik  very  light  weights   •  How  would  you  establish  func.onal  goals?   •  What  would  your  baseline  home  program  be?   •  What  methods  of  reinforcement  would  you  use?   George  and  Zeppieri  2009   11  
  • 12. 29/08/12   Review  of  PHODA   •  40  pictures  where  pa.ent  can  rate  their  level   of  fear   •  PC  only   •  hp://www.psychology.unimaas.nl/phoda-­‐ sev/Phoda-­‐SeV_UK.htm   12  
  • 13. 29/08/12   Case  study   •  25  year  old  FT  marke.ng  student   –  Referred  by  Metro  Spinal   –  DASS  –  moderate  depression  and  anxiety   –  Marked  maladap.ve  cure  focus   –  Unable  to  return  play  netball   •  What  interven.on  (psych  FC)   •  Role  play  session  1  explana.on   •  Swap  and  role  play  overcoming  an  increase  in   pain   Case  study   •  50  year  old  home  mum  with  adult  children   –  TAC  with  moderate  PTSD   –  Concurrent  moderate  severity  chronic  pain  problem   –  Socially  isolated  and  cannot  drive   –  Psychology  has  not  helped   –  10  sessions  physio  before  termina.on  of  all  medical   and  like   •  What  interven.on?   •  Role  play  iden.fica.on  of  hierarchical  list  fears   •  Plan  an  an.cipated  progression  of  ac.vity/ situa.on  over  10  sessions   13  
  • 14. 29/08/12   Contact   E:    stopsbackpain@gmail.com   W:      www.facebook.com/STOPSbackpain   T:    @stopsbackpain   14