1. ReVeaLD: A User-driven
Domain Specific Interactive Search
Platform for Biomedical Research
Maulik R. Kamdar, Ali Hasnain, Helena F. Deus
 Copyright 2011 Digital Enterprise Research Institute. All rights reserved.
Enabling Networked Knowledge

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3. “Are there Drugs with molecular weight
~300 000
under 400 tested against ‘Colon Cancer’?”
compounds
~300 interesting
compounds
~ 10 interesting
compounds
Query databases
Virtual Screening
~5 compounds
Literature
(Linked) Data
Hypothesis
Generation
“Do any Publications refer to assays using ‘Aspirin’ as
the primary Drug in treatment of ‘Prostrate Cancer’?
Enabling Networked Knowledge

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Hasnain et. al., EKAW 2012
Enabling Networked Knowledge

8. CanCO Query
Query Logging
Saved
Queries
SPARQL
Query Engine ?molec a Granatum:Molecule
RDFization Transformation
Experimental Chebi:Compound void-ext:subClassOf Granatum:Molecule
Datasets Rule Templates DrugBank:Drug void-ext:subClassOf Granatum:Molecule
Transformed Transformed Transformed Transformed
Social Collaborative Query Query Query Query
Workspace
LSLOD
Catalogue
Chebi DrugBank UniProt Others
?molec a Chebi:Compound
Cataloguing &
Links Creation
?molec a DrugBank:Drug
Life Sciences Linked Open Data
(LSLOD)
Enabling Networked Knowledge

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Availability: http://srvgal78.deri.ie:8080
Enabling Networked Knowledge

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14. PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>
PREFIX granatum: <http://chem.deri.ie/granatum/>
PREFIX uniprot: <http://bio2rdf.org/ns/uniprot:>
PREFIX dc: <http://purl.org/dc/elements/1.1/>
SELECT DISTINCT * WHERE {
?x0_Journal_Citation a uniprot:Journal_Citation ;
uniprot:pages ?x1_pages ;
dc:identifier ?x2_identifier ;
uniprot:volume ?x3_volume ;
uniprot:date ?x4_date ;
uniprot:author ?x5_author ;
rdf:void ?x6_void ;
granatum:title ?x7_title .
FILTER( regex( xsd:string( ?x7_title ), "mouse", "is" ) ) .
}
Enabling Networked Knowledge

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