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AIDS CLINICAL ROUNDS
The UC San Diego AntiViral Research Center sponsors weekly
presentations by infectious disease clinicians, physicians and
researchers. The goal of these presentations is to provide the most
current research, clinical practices and trends in HIV, HBV, HCV, TB
and other infectious diseases of global significance.

The slides from the AIDS Clinical Rounds presentation that you are
about to view are intended for the educational purposes of our
audience. They may not be used for other purposes without the
presenter’s express permission.
What Happens to HIV+ Inmates
 in the SD County Jail System
  Stays in the SD County Jail
 System (at least until the MD
becomes a snitch) - Challenges
       and Opportunities

              Daniel Lee, MD
      Clinical Professor of Medicine
    UCSD Medical Center – Owen Clinic
            December 7, 2012
Outline
Difference between Jails and Prisons
Epidemiology of HIV in Corrections
Tour of the San Diego County Jail system
Challenges and Opportunities in SD Jails
– Intake visit
– Managing HIV
– HIV testing
– Discharge
– Retention into medical care
Differences between the Jail System
              and Prison System
                      Jail                                              Prison
     Prior to sentencing                                  After sentencing
      – Awaiting trial or transfer                          – if convicted for a long time
      – Inability to post bail                            Long-term sentence
      – Detainees picked up on                              – Usually > 1 year* with mean
        suspicion of committing a                             duration of 3 years
        crime                                             More extensive amenities
     Short-term sentence                                    – Exercise areas
      – Usually < 1 year* with median                       – Common areas for eating and
        duration of 48 hours                                  socializing
     Amenities                                              – Church facilities
      – Minimal or very limited                             – Educational facility

*To deal with overcrowding in the jails, AB109 mandated that the jails would now be responsible for
taking care of inmates who are incarcerated up to 3 years
Assembly Bill 109
    Signed in 2011 by Governor Brown to reduce
    the number of inmates in the state’s 33 prisons
    by 5/24/13 as ordered by the Supreme Court
     – Allows non-violent, non-serious, and non-sex
       offenders to serve their sentence in county jails
       instead of state prisons
     – No inmates currently in state prison will be transferred
       to county jails or will be released early
     – All felons sent to state prison will continue to serve
       their entire sentence in state prison
     – All felons convicted of current or prior serious or
       violent offenses, sex offenses, and sex offenses
       against children will go to state prison
California Department of Corrections and Rehabilitation Fact Sheet, 7/15/11.
EPIDEMIOLOGY
OF HIV IN CORRECTIONS
Persons Subject to Correctional
                                        Oversight, 2010
                             8         7.08
                                                     Estimated Number of People in United States Supervised by
     Number of Individuals




                             7                           Adult Correctional Systems, by Correctional Status
                             6
         (Millions)




                             5                              4.06
                             4
                             3
                             2                                                                                    1.5
                                                                                      0.84                                                   0.75
                             1
                             0
                                 Total Population*        Probation                 Parole                      Prison‡                  Local Jails§


                                                             Community supervision                                         Incarcerated†
  Note: Estimates rounded to the nearest 100. Data may not be comparable to previously published BJS reports because of updates and changes in
                             Number of individuals released into the community annually :                                                                 2
  reference dates. Community supervision, probation, parole, and prison custody counts are for December 31 within the reporting year; jail population counts
  are for June 30. The 2007 and 2008 totals include population counts estimated by BJS because some states were unable to provide data. See Methodology.
  *Estimates were adjusted to account for some offenders with multiple correctional statuses. Details may not sum to total. See Methodology.

                                                          Jails → 8,600,000
  †Includes jail inmates and prisoners held in privately operated facilities.

  ‡Includes prisoners held in the custody of state or federal correctional facilities or privately operated facilities under state or federal authority. The custody

  prison population is not comparable to the jurisdiction prison population. See the text box on page 2 for a discussion about the differences between the two
  prison populations.
                                                         Prisons → 597,000
  §Estimates were revised to include all inmates confined in local jails, including inmates under the age of 18 years who were tried or awaiting trial as an adult

  and the number held as juveniles. Totals for 2000 and 2006 through 2010 are estimates based on the Annual Survey of Jails. See appendix table 4 for
  standard errors. Total for 2005 is a complete enumeration based on the 2005 Census of Jail Inmates. See Methodology.
1. Glaze LE. Correctional Populations in the United States, 2010. Washington, DC: Bureau of Justice Statistics; December 15, 2011.
2. Springer SA, et al. CID. 2011;53:469-479.
HIV and AIDS: US Population vs.
              Imprisoned Population
               In the US, HIV is approximately 3 times more prevalent
                     and AIDS is 2.5 times more prevalent among
                imprisoned people compared with the US population*


                                 Total number of HIV-infected inmates
                                   or inmates with confirmed AIDS
                                    held in state or federal prisons
                                         at year’s end in 2008:

                           21,987 (1.5% total population)*


                    *Data as of 12/31/2008 (most recent available)

CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011.
*Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
Number of HIV Infections in
   Incarcerated Populations by State*
                 9 states have >500 inmates with HIV infection† 
                                                                                Nine states have <20
                                                                                inmates with HIV
                                                                                infection: Alaska, Maine,
                                                                                Montana, Nebraska, New
                                                                                Hampshire, North Dakota,
                                                                                South Dakota, Vermont,
                                                                                and Wyoming




    *Information not available for Indiana
    † Data as of 12/31/2008 (most recent available); includes inmates of both state and federal prisons
Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
Rate of HIV Infection in
     Incarcerated Populations by State*
                                             11 states have higher-than-average rates
                                            of HIV infection in imprisoned populations†




     *Information not available for Indiana
     † Data as of 12/31/2008 (most recent available); includes inmates of both state and federal prisons


Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
HIV Infections by Incarceration,
                    Status, and Sex
            In the US, most people infected with HIV are male.
     The difference is more pronounced in the imprisoned population*

                            US Population                                Imprisoned Population
                           with HIV Infection                              with HIV Infection




     *Data as of
     12/31/2008
    (most recent
      available)

CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011.
Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
Rates of HIV Infection are Higher in
Incarcerated Women Compared to Men
       Compared with the US population, rates of HIV infection are
10 times higher in women and 3 times higher in men who are incarcerated



                                                                                                       In the US in 2008, 24%
                                                                                                        of new HIV infections
                                                                                                           were in women.

                                                                                                       85% of these women
                                                                                                       were infected through
                                                                                                       heterosexual contact.




  *Data as of 12/31/2008 (most recent available)

 CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011.
 Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
US and Imprisoned Populations
                   by Race/Ethnicity
                       People of color are also overrepresented
                            in the imprisoned population
                     US Population*                                                            Imprisoned Population†
                       (N=310,200,000)                                                                    (N=1,548,700)

                                                                      White

                                                                       Hispanic/
                                                                       Latino
                                                                       Black/African
                                                                       American
                                                                       Other




 No recent data exist on the racial/ethnic distribution of HIV infection among inmates in the US
 *Projected data for 2010
 †Estimated data as of 12/31/2009 (most recent available), including inmates of both state and federal prisons
Kaiser Family Foundation. Distribution of US population by race/ethnicity, 2010 and 2050. facts.kff.org/chart.aspx?ch=364. Accessed February 28, 2011.
US Department of Justice. Prisoners in 2009. bjs.ojp.usdoj.gov/content/pub/pdf/p09.pdf. Accessed February 22, 2011.
Leading Causes of Death
                       in Federal Prisons
     Within federal prisons, AIDS is the third leading cause of death*




     *Data from 2008 (most recent available), including federal agency-managed institutions only
     †50% of accidental deaths were due to drug or alcohol intoxication
Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
Rate of AIDS-Related Deaths
      in State Prisons by Race/Ethnicity
                    Within the state prison system, people of color
                    are more likely to die from AIDS-related causes*




                *Data from 2007 (most recent available)
Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
Polling Question #1
If you were arrested, who do you want to
be your best friend?
1.   “C/O”
2.   “Doc”
3.   “Cellie”
4.   “Greenbander”
Polling Question #1
If you were arrested, who do you want to
be your best friend?
1.   “C/O”
2.   “Doc”
3.   “Cellie”
4.   “Greenbander”

The answer is probably 1, 2, or 3 (depending on
what you need)
SAN DIEGO COUNTY JAILS
San Diego County Jail System
San Diego Central Jail (SDCJ)

George Bailey Detention Facility (GBDF)

Vista Detention Facility (VDF)

Facility 8 Detention Facility (F8DF)

East Mesa Detention Facility (EMDF)

South Bay Detention Facility (SBDF)

Las Colinas Detention Facility (LCDF)
HIV Care at San Diego Jails
Jail medical care in San Diego is
currently provided by UCSD
Emergency Medicine Department
HIV specialty care is subcontracted
out to Owen Clinic
– All HIV+ inmates are sent to
  SDCJ for HIV medical care
– Weekly HIV Clinic on Tuesday
  PMs (direct patient care) at San
  Diego Central Jail since 12/28/98
– Average of 10-15 inmates/week
  (Range 5-20)
San Diego Central Jail
San Diego Central Jail
San Diego Central Jail
Jail Entry and Intake
Inmates are seen by physician for initial
medical intake visit
– Review of past medical history
– Medications for acute or chronic medical
  conditions may be started
    HAART may or may not be started
– Labs may be ordered if needed
    HIV-specific labs may or may not be ordered
– Old records are ordered
– Referred to Tuesday PM clinic for HIV-specific
  care
Tuesday 1PM HIV Clinic
Inmates are sent from outside jails and transferred early
in the AM to SDCJ
– Assessment of jail-related factors – may affect plan of action
      When is the upcoming court date?
      Likelihood of release?
      Prison time or not?
– Review of HIV-related history/ARV history and old
  records/UCSD records (EPIC)
– Consider restarting HAART
– Consider ordering HIV-specific labs
– Address other concerns
      Diet
      “Chronos”
– Transitional case manager assessment of inmate interest in
  drug/EtOH rehabilitation programs
Factors to Consider When Starting
          HAART in a Correctional Setting
           Incarcerated patients face additional challenges with
           antiretroviral therapy, including:
             – Confidentiality
             – Necessity of visiting medication lines on a regular basis
             – Distribution methods: keep on person (KOP) or directly-observed
               therapy (DOT)
             – Availability of food and water may not correspond with conditions
               needed for specific antiretroviral medications
             – Detention in segregation or other area where medications are
               not accessible
             – Policies and procedures focused on security that may not allow
               for needed flexibility

AIDS Education and Training Centers National Resource Center. Correctional Settings. http://www.aids-ed.org/aidsetc?page=cm-801_corrections. Accessed April 12, 2011.
Stephenson B, Leone P. HIV care in U.S. prisons: the potential and challenge. www.thebodypro.com/content/art14528.html. Accessed April 12, 2011.
Polling Question #2
In addition to starting HAART, let’s
assume you were also trying to “score”
pain medications, what is the most likely
diagnosis you should claim to have?
1.   Back pain
2.   Toothache
3.   Neuropathy
4.   Rib pain
5.   None, just trade with someone who gets it
     “legit”
Polling Question #2
In addition to starting HAART, let’s
assume you were also trying to “score”
pain medications, what is the most likely
diagnosis you should claim to have?
1. Back pain
2. Toothache
3. Neuropathy
4. Rib pain
5. None, just trade with someone who gets it
   “legit”
The correct answer is Neuropathy
HIV Testing Is Underutilized
                                      in the Corrections System
                             25
                                    23                                                   Many prison systems provide
                                                                                         testing on request or based on
                             20                                                          clinical indication or risk factors
                                                                                         Only 2 states (Missouri and
       States Testing, No.




                             15                                                          Nevada) test at all 3 time
                                                                                         points
                             10
                                                                                         Not all states use opt-out
                                                                                         testing practices as
                                                                 6                       recommended by the Centers
                                                 5
                             5
                                                                                         for Disease Control and
                                                                                         Prevention (CDC)
                             0
                                  Entering   In Custody   On Release
                                  Custody

Dwyer M, et al; HIV/AIDS Bureau. HIV care in correctional settings. Guide for HIV/AIDS Clinical Care. Rockville, MD: Health Resources and Services
Administration; January 2011.
HIV Screening Is Cost Effective Even When
            the Prevalence Is Substantially <1%
                                                    Cost-effectiveness of a One-time Screening Program
                                                        vs No Screening in the General Population1
                   Incremental Cost-Effectiveness



                                                    200,000
                                                    180,000
                        of Screening, $/QALY




                                                    160,000
                                                    140,000
                                                    120,000
                                                    100,000
                                                     80,000
                                                                                      Costs and benefits to partners excluded
                                                     60,000
                                                     40,000
                                                                                      Costs and benefits to partners included
                                                     20,000
                                                          0
                                                              0.0   0.1   0.2   0.3   0.4   0.5   0.6   0.7   0.8     0.9      1.0

                                                                          Prevalence of Unidentified HIV, %
              The prevalence of HIV in many incarcerated populations is >1%2
                – CDC3: Patients aged 13-64 years should be screened for HIV in settings with
                  prevalence ≥0.1%
                QALY, quality-adjusted life year.
1. Adapted from Sanders GD, et al. N Engl J Med. 2005;352:570-585. ®New England Journal of Medicine. 2. Beckwith C, et al; Centers for Disease Control and
Prevention. HIV Testing Implementation Guidance for Correctional Settings. Atlanta, GA: Centers for Disease Control and Prevention, US Department of Health
& Human Services: January 2009: 1-38. 3. Viall AH, et al; Centers for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep. 2011;60:805-810.
Testing Programs Can Bridge the Gap
          from Custody to Community

         Individuals unaware of their HIV-positive
         status are 3.5 times more likely to transmit
         the virus
         Testing, upon intake, is especially important
         for jail inmates due to typically shorter stays
         Knowledge of HIV status lowers risk-taking
         behaviors with others by 50%

Altice FL, et al. Jail: time for testing. www.enhancelink.org/sites/hivjailstudy/Training Manual ready to print.pdf. Accessed March 19, 2012.
HIV-Related Testing and Post-
 Exposure Prophylaxis at SDCJ
HIV-related tests
– HIV antibody testing is not proactively offered at intake or at
  discharge, but available upon request
– HIV rapid tests are not available
– HIV antibody tests consist of EIA with confirmatory CIA –
  turnaround time ~ 2 wks
– All those tested for HIV are referred to Tuesday PM for review of
  HIV test results
– CD4/VL (RNA PCR tests) – turnaround time ~2 wks
– HIV Genotype testing (Quest) – turnaround time ~2-4 wks
Post-exposure prophylaxis
– All inmates are started on LPV/RTV with TDF/FTC and single-
  dose NVP x 28 days and HIV antibody testing sent
Polling Question #3
What is the most commonly “cheeked”
non-narcotic pain medication?
1.   Ibuprofen
2.   Tramadol
3.   Gabapentin
4.   Indocin
Polling Question #3
What is the most commonly “cheeked”
non-narcotic pain medication?
1.   Ibuprofen
2.   Tramadol
3.   Gabapentin
4.   Indocin

The correct answer is tramadol, but gabapentin
is a common as well
Jail Discharge at SDCJ
Inmates are discharged typically in late
evening/early morning by discharge MD
– Psych medications are given upon discharge
– A prescription for a 30-day supply of HIV
  medications is given to the inmate or faxed to
  Hillcrest Pharmacy (contract with Jail to
  supply HIV medications) if written by the
  discharge MD
– Other ancillary medications (ie. diabetes
  medications, antihypertensives, or pain
  medications) may or may not be written for
  upon discharge
The Transition to the Community
                Is an Especially Vulnerable Time
          Many inmates received an HIV-positive
          diagnosis while incarcerated
            – 75% initiate ART while in custody, but many
              discontinue therapy once released

          ≥90% of newly released inmates do not fill
          ART prescriptions in time to avoid treatment
          interruption
            – >80% do not fill their prescriptions within 30
              days of release
Baillargeon J, et al. JAMA. 2009;301:848-857.
The Hierarchy of Needs for the HIV-
                  infected Former Inmate
                                                                                                              Risk behavior
                                                                        HIV                                   modification



                                                               Mental illness
                                                               management



                                            Drug dependence management



                                               Case management:
                                     Shelter, food, employment, and safety

Springer SA, et al. CID. 2011;53:469-479.
Reproduced with permission of Oxford University Press in the format Journal via Copyright Clearance Center.
HIV+ Individuals Returning to the
                             Community Face Many Obstacles
                             HIV-positive South Florida Inmates
                              Require Assistance on Release1                                   Additional obstacles2
                                                                                                 – Anti-Drug Abuse Act of 1988
                             80                                                                              May be denied public
                             70    67                                                                        housing if convicted of a
       Released Inmates, %




                                                 60                                                          crime
                             60
                                                                                                 – Welfare Reform Act
                             50                               45                                             Prohibited from receiving
                             40                                                                              food stamps or federal
                                                                            30                               assistance
                             30
                                                                                                 – Reinstating Medicaid
                             20
                                                                                                   coverage may be delayed
                             10                                                                    (average of 3 months)
                              0                                                                              Benefits affected by
                                  Housing        Case      Obtaining    Substance Use                        duration of incarceration
                                              Management   Medication     Treatment
                                            Assistance Required
1. Jordan AO, et al. Policy Brief — Enhancing linkages to HIV primary care and services in jail settings initiative: transitional care coordination — from
incarceration to the community. www.enhancelink.org/sites/hivjailstudy/Policy_brief_Transitional_Care_Coordination_Final_1.27.11.pdf. Accessed March 15,
2012. 2. Wakeman SE, et al. HIV treatment in US prisons. www.medscape.com/viewarticle/725477. Accessed March 1, 2012.
One Simple Method to Reduce
                          Treatment Interruptions
             Assisting HIV-infected inmates in filling out AIDS
             Drug Assistance Program (ADAP) forms (Texas)
               – Inmates who did not receive assistance filling out
                 forms
                           5.4% filled prescriptions within 10 days after release
                           17.7% within the first 30 days
                           30% were still on therapy 60 days post-release
               – Inmates who had assistance filling out forms
                           Twice as likely to fill their initial prescriptions within 30 days
                           33.6% were still on therapy 60 days post-release



Whitten L. http://m.drugabuse.gov/news-events/nida-notes/2011/03/hiv-treatment-interruption-pervasive-after-release-texas-prisons. Accessed
February 29, 2012.
The VIBE Health Study:
Interruptions in Antiretroviral
Therapy (ART) are Common
 Following Release from Jail
 Robin A. Pollini 1, Daniel Lee 2, Ken Saragosa 2, Tim Smith 3,
           Josiah D. Rich 4, María Luisa Zúñiga 2

  1) Pacific Institute for Research and Evaluation, Calverton,
      Maryland, USA; 2) School of Medicine, University of
 California San Diego (UCSD), San Diego, California, USA; 3)
  Health and Human Services Agency, County of San Diego,
  San Diego, California, USA; 4) Brown Medical School and
        Miriam Hospital, Providence, Rhode Island, USA
Background
      HIV prevalence in U.S. prisons and jails is four
     times that of the general population1 and 1 in 7
     HIV+ persons in the U.S. passes through a
     criminal justice facility annually2
      2009 JAMA study3 found that only 5% of HIV+
     persons released from prison with a 10-day
     supply of ART filled their prescription within 10
     days, and only 18% filled the prescription within
     30 days.

1.   Maruschak 2009/10. http://bjs.ojp.usdoj.gov/content/pub/pdf/hivp08.pdf
2.   Spaulding AC, et al. HIV/AIDS among inmates of and relesees from US correctional facilities, 2006: declining share
     of epidemic but persistent public health opportunity. PLoS One. 2009;4(11):e7558.
3.   Saldana, J. (2009). The coding manual for qualitative researchers. Los Angeles, CA: SAGE.
Study Objective

 Our research team initiated the Viral
Inhibition through Better reEntry (VIBE)
Study to better understand:
– frequency and causes of post-release
  interruptions in ART among HIV+ persons
  leaving jail in San Diego County, California.
Methods
Setting: San Diego County operates 7 jail
facilities housing >5,000 inmates. HIV+
inmates treated by UCSD physicians; HIV+
inmates eligible for the County’s AIDS Case
Management Program
Recruitment: August 2010-October 2011
Eligibility: 1) 18+ years old 2) released from
SD county jail in the last 30 days 3)not
currently incarcerated 4) ever diagnosed with
HIV 5) received HIV care during their last
incarceration
Methods (con.)
Data Collection: Interviewer-administered
quantitative survey and a 1-hour qualitative
interview
Data analysis: descriptive statistics, regression
modeling to identify factors independently
associated with ART discontinuity; qualitative
interview summaries coded using descriptive
coding 3,4 to identify references to ART discontinuity
and its contributing factors
63 HIV+ recently-released individuals were
enrolled in the study
Results: ART Continuity After Jail
           Release

Of the 38 participants on ART at the time
of release
23 (61%) missed at least one dose
immediately following their release
(average number of days = 4)
Days of missed ART doses
immediately after jail release (N=38)
Results (cont.): Survey results
Most commonly cited reason for missed
doses while in jail: need for HIV physician
to prescribe medications after
incarceration
Other reasons: unavailability of
participant’s full ART regimen, provision of
incorrect drugs or dosages, not wanting to
go to HIV clinic for fear of HIV+
identification
Survey results: Reasons for missing ART doses after jail release (N=23)
                                                                  %
Didn’t have the medications                                       87
Couldn’t pay for the medications                                  26
Was using drugs or alcohol                                        9
Had medications but couldn’t get to them when needed              4

           Top priority for participants who missed ART doses
                    immediately after release (N=23)
                                                         %
           Get drug or alcohol treatment                 35
           Find housing                                  22
           Get cash                                      17
           Reunite with family, partner or friends       9
           Take care of legal problems                   4
           Use drugs or alcohol                          4
           Get HIV care/medications                      4
           Get identification                            4
Comparing those who missed doses
after jail release to those who did not:

Missing ART doses was significantly
 associated with individuals who were
 younger, who used transportation from
 treatment facilities or used public
 transportation, and reported post-release
 methamphetamine use
Results: In-depth interviews
Barriers to post-release ART missed doses
 included:
 Expiration of MediCal and/or AIDS Drug
 Assistance Program (ADAP) coverage
 Logistical issues: medications not
 delivered to drug treatment facility, lack of
 transportation
Conclusions
A majority of VIBE Study participants
missed ART doses immediately following
jail release.
Factors such as discontinued medical
insurance played a role
Participants reported competing
priorities/demands: substance abuse
treatment, housing, cash, etc.
CQI Project at SDCJ
Identifying needs of SDCJ
– Many opportunities for improvements exist
– Needs identified by administration
    Lack of HIV specialty care
     – Driven by concern for lawsuits
     – Disinterest by jail doctors to assume care of HIV inmates
– Needs identified by consultant/care provider
    Improve HIV-related care at SDCJ
     – HAART initiation, management
     – Diagnose/manage HIV specific conditions including OIs
     – Post-exposure prophylaxis and HIV post-test counseling
CQI Project at SDCJ
Planning and implementing interventions
(buy-in) to address needs
– Not too difficult as long as interventions were
  “simple, cost-effective, and prevent lawsuits”
    Simple = minimal disruption to nursing staff and
    officers
    Cost-effective = not costing too much extra or
    breaking the budget
    Prevent complaints/lawsuits (unstated) – likely true
    though
Administrative Obstacles
           Obstacle                   Intervention                    Outcome
                                    Provide consultation and     Continued improvement
1.   Lack of HIV specialty care
                                    direct HIV care              of HIV care
                                    No intervention yet.         No change, but lead by
2.   Disinterest of physicians
                                    Consider more education      example
                                    No intervention yet.         No change, but lead by
3.   Disinterest of nursing staff
                                    Consider more education      example
                                    No intervention yet.         No change, but lead by
4.   Disinterest of officers
                                    Consider more education      example
                                    Some education provided      Some improvement of
5.   Disinterest of pharmacists
                                    through direct interaction   identification of errors
                                                              No restriction on use of
     Perceived high costs of HIV    Education of cost and
                                                              HAART, but less difficulty
6.   drugs (use of generic          risk/benefit of HAART and
                                                              w/obtaining resistance
     drugs?)/resistance testing     resistance testing
                                                              testing now
HIV Medical Care Obstacles
           Obstacle                  Intervention                   Outcome
     Delay in initiating/resuming                              Usually started within a
1.                                  None, seen by intake MD
     HAART                                                     few days, w/exceptions
                                    Weekly review of all HIV   Less medication errors,
2.   HIV medication errors          meds for all SDCJ          but disincentive for jail
                                    inmates                    staff to learn
     Inmates may refuse to
3.                                  None                       No change
     come to clinic due to stigma
     Discharge inmates with HIV     Discussion with nurses     Variable and dependent
4.
     medications                    emphasizing importance     on discharge RN & MD
                                    Work with transitional     Improved transition of
     Inmates lost to followup on
                                    case managers to place     care back with their HIV
5.   discharge, high recidivism
                                    inmates in drug rehab      primary care provider,
     rates
                                    programs/placement         decreased recidivism
                                    Implemented VIBE study     Identified gaps in the
     Transitional care upon
6.                                  to look at transitional    area of discharging
     release from jail
                                    care                       inmates with HIV meds
Number of Inmates




                0
                    5
                        10
                             15
                                               20
                                                             25
                                                                            30
                                                                                 35
                                                                                      40
                                                                                           45
        1/15/2008
        2/15/2008
        3/15/2008
        4/15/2008
        5/15/2008
        6/15/2008
        7/15/2008
        8/15/2008
        9/15/2008
       10/15/2008
       11/15/2008
       12/15/2008
        1/15/2009
        2/15/2009
        3/15/2009
        4/15/2009
        5/15/2009
        6/15/2009
        7/15/2009




Week
        8/15/2009
        9/15/2009
       10/15/2009
       11/15/2009
       12/15/2009
        1/15/2010
        2/15/2010
        3/15/2010
        4/15/2010
        5/15/2010
        6/15/2010
        7/15/2010
                                                                                                HIV+ Inmates in San Diego County Jails




        8/15/2010
        9/15/2010
       10/15/2010
       11/15/2010
                                                             VDF
                                                      FAC8
                                                                          SDCJ




                                               LCDF
                                                                   GBDF




                                        EMDF
                              Total #
Number of Errors




                0
                          1
                                    2
                                                       3
                                                                 4




                              1.5
                                                 2.5
                                                           3.5
                                                                     4.5




                    0.5
        1/15/2008
        2/15/2008
        3/15/2008
        4/15/2008
        5/15/2008
        6/15/2008
        7/15/2008
        8/15/2008
        9/15/2008
       10/15/2008
       11/15/2008
       12/15/2008
        1/15/2009
        2/15/2009
        3/15/2009
        4/15/2009
        5/15/2009
        6/15/2009
        7/15/2009




Week
        8/15/2009
        9/15/2009
       10/15/2009
       11/15/2009
       12/15/2009
        1/15/2010
        2/15/2010
        3/15/2010
        4/15/2010
        5/15/2010
        6/15/2010
        7/15/2010
                                                                           ARV Prescription Errors in San Diego County Jails




        8/15/2010
        9/15/2010
       10/15/2010
       11/15/2010
                                        Errors
ARV Medication Errors
Total of 86 errors over 126 weeks of ARV review
– from 83 providers (37 unique providers)
– 3 providers with 2 different errors
Errors per week
– Mean = 0.68 errors/week
Range = 0-4 errors/week
Errors per provider
– Median = 1 error/week
– Range = 1-9 errors
– 16 providers with 2 or more errors
ARV Medication Errors
 Type of Errors:

1 Less than 3 ARV drugs                     30
2 Incorrect dose of ARV drug                37
3 Incorrect frequency of ARV drug           9
4 ARV interaction                           1
5 MD error (ie. Zerit instead of Zestril)   5
6 Missing Ritonavir as a Booster PI         1
7 Missing PI with Ritonavir                 1
8 Too many ARV agents                       1
9 Written for same drug twice               1
Summary and Future Directions
Many opportunities exist for continued
improvement in the delivery of quality HIV care
in inmates at SDCJ
 – Has been successful in some areas
 – Require buy-in and support of administration and all
   those involved in care
Future directions
 – Continue multi-pronged CQI projects
 – Continue providing education and developing rapport
   and collaborations with those interested in HIV care
Acknowledgments
Colleagues who have shared       Emergency Department
the burden of work at the jail   Physicians
–   Chris Mathews                – Ted Chan
–   Theo Katsivas
                                 – Gary Vilke
–   Alfredo Tiu
–   Tyler Lonergan               SDCJ Staff
Transitional Case Managers       –   Earl Goldstein
–   Rafaela Jennings             –   Sue Smith
–   Sonja Proctor                –   Terry Zakosky
–   Amy Applebaum                –   Chris McClean
–   Tim Smith                    SDCJ Pharmacy Staff
VIBE Study Staff                 – Jeffrey Crutchfield
–   Robin Pollini                – Ashley Clark
–   Mari Zuniga                  – Ida Bleich
–   Ken Saragosa
–   Serena Ruiz

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What Happens to HIV+ Inmates in the SD County Jail System, Stays in the SD County Jail System: Challenges and Opportunities

  • 1. AIDS CLINICAL ROUNDS The UC San Diego AntiViral Research Center sponsors weekly presentations by infectious disease clinicians, physicians and researchers. The goal of these presentations is to provide the most current research, clinical practices and trends in HIV, HBV, HCV, TB and other infectious diseases of global significance. The slides from the AIDS Clinical Rounds presentation that you are about to view are intended for the educational purposes of our audience. They may not be used for other purposes without the presenter’s express permission.
  • 2. What Happens to HIV+ Inmates in the SD County Jail System Stays in the SD County Jail System (at least until the MD becomes a snitch) - Challenges and Opportunities Daniel Lee, MD Clinical Professor of Medicine UCSD Medical Center – Owen Clinic December 7, 2012
  • 3. Outline Difference between Jails and Prisons Epidemiology of HIV in Corrections Tour of the San Diego County Jail system Challenges and Opportunities in SD Jails – Intake visit – Managing HIV – HIV testing – Discharge – Retention into medical care
  • 4. Differences between the Jail System and Prison System Jail Prison Prior to sentencing After sentencing – Awaiting trial or transfer – if convicted for a long time – Inability to post bail Long-term sentence – Detainees picked up on – Usually > 1 year* with mean suspicion of committing a duration of 3 years crime More extensive amenities Short-term sentence – Exercise areas – Usually < 1 year* with median – Common areas for eating and duration of 48 hours socializing Amenities – Church facilities – Minimal or very limited – Educational facility *To deal with overcrowding in the jails, AB109 mandated that the jails would now be responsible for taking care of inmates who are incarcerated up to 3 years
  • 5. Assembly Bill 109 Signed in 2011 by Governor Brown to reduce the number of inmates in the state’s 33 prisons by 5/24/13 as ordered by the Supreme Court – Allows non-violent, non-serious, and non-sex offenders to serve their sentence in county jails instead of state prisons – No inmates currently in state prison will be transferred to county jails or will be released early – All felons sent to state prison will continue to serve their entire sentence in state prison – All felons convicted of current or prior serious or violent offenses, sex offenses, and sex offenses against children will go to state prison California Department of Corrections and Rehabilitation Fact Sheet, 7/15/11.
  • 7. Persons Subject to Correctional Oversight, 2010 8 7.08 Estimated Number of People in United States Supervised by Number of Individuals 7 Adult Correctional Systems, by Correctional Status 6 (Millions) 5 4.06 4 3 2 1.5 0.84 0.75 1 0 Total Population* Probation Parole Prison‡ Local Jails§ Community supervision Incarcerated† Note: Estimates rounded to the nearest 100. Data may not be comparable to previously published BJS reports because of updates and changes in Number of individuals released into the community annually : 2 reference dates. Community supervision, probation, parole, and prison custody counts are for December 31 within the reporting year; jail population counts are for June 30. The 2007 and 2008 totals include population counts estimated by BJS because some states were unable to provide data. See Methodology. *Estimates were adjusted to account for some offenders with multiple correctional statuses. Details may not sum to total. See Methodology. Jails → 8,600,000 †Includes jail inmates and prisoners held in privately operated facilities. ‡Includes prisoners held in the custody of state or federal correctional facilities or privately operated facilities under state or federal authority. The custody prison population is not comparable to the jurisdiction prison population. See the text box on page 2 for a discussion about the differences between the two prison populations. Prisons → 597,000 §Estimates were revised to include all inmates confined in local jails, including inmates under the age of 18 years who were tried or awaiting trial as an adult and the number held as juveniles. Totals for 2000 and 2006 through 2010 are estimates based on the Annual Survey of Jails. See appendix table 4 for standard errors. Total for 2005 is a complete enumeration based on the 2005 Census of Jail Inmates. See Methodology. 1. Glaze LE. Correctional Populations in the United States, 2010. Washington, DC: Bureau of Justice Statistics; December 15, 2011. 2. Springer SA, et al. CID. 2011;53:469-479.
  • 8. HIV and AIDS: US Population vs. Imprisoned Population In the US, HIV is approximately 3 times more prevalent and AIDS is 2.5 times more prevalent among imprisoned people compared with the US population* Total number of HIV-infected inmates or inmates with confirmed AIDS held in state or federal prisons at year’s end in 2008: 21,987 (1.5% total population)* *Data as of 12/31/2008 (most recent available) CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011. *Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 9. Number of HIV Infections in Incarcerated Populations by State* 9 states have >500 inmates with HIV infection†  Nine states have <20 inmates with HIV infection: Alaska, Maine, Montana, Nebraska, New Hampshire, North Dakota, South Dakota, Vermont, and Wyoming *Information not available for Indiana † Data as of 12/31/2008 (most recent available); includes inmates of both state and federal prisons Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 10. Rate of HIV Infection in Incarcerated Populations by State* 11 states have higher-than-average rates of HIV infection in imprisoned populations† *Information not available for Indiana † Data as of 12/31/2008 (most recent available); includes inmates of both state and federal prisons Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 11. HIV Infections by Incarceration, Status, and Sex In the US, most people infected with HIV are male. The difference is more pronounced in the imprisoned population* US Population Imprisoned Population with HIV Infection with HIV Infection *Data as of 12/31/2008 (most recent available) CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011. Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 12. Rates of HIV Infection are Higher in Incarcerated Women Compared to Men Compared with the US population, rates of HIV infection are 10 times higher in women and 3 times higher in men who are incarcerated In the US in 2008, 24% of new HIV infections were in women. 85% of these women were infected through heterosexual contact. *Data as of 12/31/2008 (most recent available) CDC. HIV/AIDS surveillance report, 2009. Vol. 21. www.cdc.gov/hiv/surveillance/resources/reports/2009report. Accessed February 28, 2011. Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 13. US and Imprisoned Populations by Race/Ethnicity People of color are also overrepresented in the imprisoned population US Population* Imprisoned Population† (N=310,200,000) (N=1,548,700) White Hispanic/ Latino Black/African American Other No recent data exist on the racial/ethnic distribution of HIV infection among inmates in the US *Projected data for 2010 †Estimated data as of 12/31/2009 (most recent available), including inmates of both state and federal prisons Kaiser Family Foundation. Distribution of US population by race/ethnicity, 2010 and 2050. facts.kff.org/chart.aspx?ch=364. Accessed February 28, 2011. US Department of Justice. Prisoners in 2009. bjs.ojp.usdoj.gov/content/pub/pdf/p09.pdf. Accessed February 22, 2011.
  • 14. Leading Causes of Death in Federal Prisons Within federal prisons, AIDS is the third leading cause of death* *Data from 2008 (most recent available), including federal agency-managed institutions only †50% of accidental deaths were due to drug or alcohol intoxication Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 15. Rate of AIDS-Related Deaths in State Prisons by Race/Ethnicity Within the state prison system, people of color are more likely to die from AIDS-related causes* *Data from 2007 (most recent available) Maruschak LM, Beavers R. HIV in Prisons 2007-08. NCJ 228307. Revised 1/28/10.
  • 16. Polling Question #1 If you were arrested, who do you want to be your best friend? 1. “C/O” 2. “Doc” 3. “Cellie” 4. “Greenbander”
  • 17. Polling Question #1 If you were arrested, who do you want to be your best friend? 1. “C/O” 2. “Doc” 3. “Cellie” 4. “Greenbander” The answer is probably 1, 2, or 3 (depending on what you need)
  • 19. San Diego County Jail System San Diego Central Jail (SDCJ) George Bailey Detention Facility (GBDF) Vista Detention Facility (VDF) Facility 8 Detention Facility (F8DF) East Mesa Detention Facility (EMDF) South Bay Detention Facility (SBDF) Las Colinas Detention Facility (LCDF)
  • 20. HIV Care at San Diego Jails Jail medical care in San Diego is currently provided by UCSD Emergency Medicine Department HIV specialty care is subcontracted out to Owen Clinic – All HIV+ inmates are sent to SDCJ for HIV medical care – Weekly HIV Clinic on Tuesday PMs (direct patient care) at San Diego Central Jail since 12/28/98 – Average of 10-15 inmates/week (Range 5-20)
  • 24. Jail Entry and Intake Inmates are seen by physician for initial medical intake visit – Review of past medical history – Medications for acute or chronic medical conditions may be started HAART may or may not be started – Labs may be ordered if needed HIV-specific labs may or may not be ordered – Old records are ordered – Referred to Tuesday PM clinic for HIV-specific care
  • 25. Tuesday 1PM HIV Clinic Inmates are sent from outside jails and transferred early in the AM to SDCJ – Assessment of jail-related factors – may affect plan of action When is the upcoming court date? Likelihood of release? Prison time or not? – Review of HIV-related history/ARV history and old records/UCSD records (EPIC) – Consider restarting HAART – Consider ordering HIV-specific labs – Address other concerns Diet “Chronos” – Transitional case manager assessment of inmate interest in drug/EtOH rehabilitation programs
  • 26. Factors to Consider When Starting HAART in a Correctional Setting Incarcerated patients face additional challenges with antiretroviral therapy, including: – Confidentiality – Necessity of visiting medication lines on a regular basis – Distribution methods: keep on person (KOP) or directly-observed therapy (DOT) – Availability of food and water may not correspond with conditions needed for specific antiretroviral medications – Detention in segregation or other area where medications are not accessible – Policies and procedures focused on security that may not allow for needed flexibility AIDS Education and Training Centers National Resource Center. Correctional Settings. http://www.aids-ed.org/aidsetc?page=cm-801_corrections. Accessed April 12, 2011. Stephenson B, Leone P. HIV care in U.S. prisons: the potential and challenge. www.thebodypro.com/content/art14528.html. Accessed April 12, 2011.
  • 27. Polling Question #2 In addition to starting HAART, let’s assume you were also trying to “score” pain medications, what is the most likely diagnosis you should claim to have? 1. Back pain 2. Toothache 3. Neuropathy 4. Rib pain 5. None, just trade with someone who gets it “legit”
  • 28. Polling Question #2 In addition to starting HAART, let’s assume you were also trying to “score” pain medications, what is the most likely diagnosis you should claim to have? 1. Back pain 2. Toothache 3. Neuropathy 4. Rib pain 5. None, just trade with someone who gets it “legit” The correct answer is Neuropathy
  • 29. HIV Testing Is Underutilized in the Corrections System 25 23 Many prison systems provide testing on request or based on 20 clinical indication or risk factors Only 2 states (Missouri and States Testing, No. 15 Nevada) test at all 3 time points 10 Not all states use opt-out testing practices as 6 recommended by the Centers 5 5 for Disease Control and Prevention (CDC) 0 Entering In Custody On Release Custody Dwyer M, et al; HIV/AIDS Bureau. HIV care in correctional settings. Guide for HIV/AIDS Clinical Care. Rockville, MD: Health Resources and Services Administration; January 2011.
  • 30. HIV Screening Is Cost Effective Even When the Prevalence Is Substantially <1% Cost-effectiveness of a One-time Screening Program vs No Screening in the General Population1 Incremental Cost-Effectiveness 200,000 180,000 of Screening, $/QALY 160,000 140,000 120,000 100,000 80,000 Costs and benefits to partners excluded 60,000 40,000 Costs and benefits to partners included 20,000 0 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 Prevalence of Unidentified HIV, % The prevalence of HIV in many incarcerated populations is >1%2 – CDC3: Patients aged 13-64 years should be screened for HIV in settings with prevalence ≥0.1% QALY, quality-adjusted life year. 1. Adapted from Sanders GD, et al. N Engl J Med. 2005;352:570-585. ®New England Journal of Medicine. 2. Beckwith C, et al; Centers for Disease Control and Prevention. HIV Testing Implementation Guidance for Correctional Settings. Atlanta, GA: Centers for Disease Control and Prevention, US Department of Health & Human Services: January 2009: 1-38. 3. Viall AH, et al; Centers for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep. 2011;60:805-810.
  • 31. Testing Programs Can Bridge the Gap from Custody to Community Individuals unaware of their HIV-positive status are 3.5 times more likely to transmit the virus Testing, upon intake, is especially important for jail inmates due to typically shorter stays Knowledge of HIV status lowers risk-taking behaviors with others by 50% Altice FL, et al. Jail: time for testing. www.enhancelink.org/sites/hivjailstudy/Training Manual ready to print.pdf. Accessed March 19, 2012.
  • 32. HIV-Related Testing and Post- Exposure Prophylaxis at SDCJ HIV-related tests – HIV antibody testing is not proactively offered at intake or at discharge, but available upon request – HIV rapid tests are not available – HIV antibody tests consist of EIA with confirmatory CIA – turnaround time ~ 2 wks – All those tested for HIV are referred to Tuesday PM for review of HIV test results – CD4/VL (RNA PCR tests) – turnaround time ~2 wks – HIV Genotype testing (Quest) – turnaround time ~2-4 wks Post-exposure prophylaxis – All inmates are started on LPV/RTV with TDF/FTC and single- dose NVP x 28 days and HIV antibody testing sent
  • 33. Polling Question #3 What is the most commonly “cheeked” non-narcotic pain medication? 1. Ibuprofen 2. Tramadol 3. Gabapentin 4. Indocin
  • 34. Polling Question #3 What is the most commonly “cheeked” non-narcotic pain medication? 1. Ibuprofen 2. Tramadol 3. Gabapentin 4. Indocin The correct answer is tramadol, but gabapentin is a common as well
  • 35. Jail Discharge at SDCJ Inmates are discharged typically in late evening/early morning by discharge MD – Psych medications are given upon discharge – A prescription for a 30-day supply of HIV medications is given to the inmate or faxed to Hillcrest Pharmacy (contract with Jail to supply HIV medications) if written by the discharge MD – Other ancillary medications (ie. diabetes medications, antihypertensives, or pain medications) may or may not be written for upon discharge
  • 36. The Transition to the Community Is an Especially Vulnerable Time Many inmates received an HIV-positive diagnosis while incarcerated – 75% initiate ART while in custody, but many discontinue therapy once released ≥90% of newly released inmates do not fill ART prescriptions in time to avoid treatment interruption – >80% do not fill their prescriptions within 30 days of release Baillargeon J, et al. JAMA. 2009;301:848-857.
  • 37. The Hierarchy of Needs for the HIV- infected Former Inmate Risk behavior HIV modification Mental illness management Drug dependence management Case management: Shelter, food, employment, and safety Springer SA, et al. CID. 2011;53:469-479. Reproduced with permission of Oxford University Press in the format Journal via Copyright Clearance Center.
  • 38. HIV+ Individuals Returning to the Community Face Many Obstacles HIV-positive South Florida Inmates Require Assistance on Release1 Additional obstacles2 – Anti-Drug Abuse Act of 1988 80 May be denied public 70 67 housing if convicted of a Released Inmates, % 60 crime 60 – Welfare Reform Act 50 45 Prohibited from receiving 40 food stamps or federal 30 assistance 30 – Reinstating Medicaid 20 coverage may be delayed 10 (average of 3 months) 0 Benefits affected by Housing Case Obtaining Substance Use duration of incarceration Management Medication Treatment Assistance Required 1. Jordan AO, et al. Policy Brief — Enhancing linkages to HIV primary care and services in jail settings initiative: transitional care coordination — from incarceration to the community. www.enhancelink.org/sites/hivjailstudy/Policy_brief_Transitional_Care_Coordination_Final_1.27.11.pdf. Accessed March 15, 2012. 2. Wakeman SE, et al. HIV treatment in US prisons. www.medscape.com/viewarticle/725477. Accessed March 1, 2012.
  • 39. One Simple Method to Reduce Treatment Interruptions Assisting HIV-infected inmates in filling out AIDS Drug Assistance Program (ADAP) forms (Texas) – Inmates who did not receive assistance filling out forms 5.4% filled prescriptions within 10 days after release 17.7% within the first 30 days 30% were still on therapy 60 days post-release – Inmates who had assistance filling out forms Twice as likely to fill their initial prescriptions within 30 days 33.6% were still on therapy 60 days post-release Whitten L. http://m.drugabuse.gov/news-events/nida-notes/2011/03/hiv-treatment-interruption-pervasive-after-release-texas-prisons. Accessed February 29, 2012.
  • 40. The VIBE Health Study: Interruptions in Antiretroviral Therapy (ART) are Common Following Release from Jail Robin A. Pollini 1, Daniel Lee 2, Ken Saragosa 2, Tim Smith 3, Josiah D. Rich 4, María Luisa Zúñiga 2 1) Pacific Institute for Research and Evaluation, Calverton, Maryland, USA; 2) School of Medicine, University of California San Diego (UCSD), San Diego, California, USA; 3) Health and Human Services Agency, County of San Diego, San Diego, California, USA; 4) Brown Medical School and Miriam Hospital, Providence, Rhode Island, USA
  • 41. Background HIV prevalence in U.S. prisons and jails is four times that of the general population1 and 1 in 7 HIV+ persons in the U.S. passes through a criminal justice facility annually2 2009 JAMA study3 found that only 5% of HIV+ persons released from prison with a 10-day supply of ART filled their prescription within 10 days, and only 18% filled the prescription within 30 days. 1. Maruschak 2009/10. http://bjs.ojp.usdoj.gov/content/pub/pdf/hivp08.pdf 2. Spaulding AC, et al. HIV/AIDS among inmates of and relesees from US correctional facilities, 2006: declining share of epidemic but persistent public health opportunity. PLoS One. 2009;4(11):e7558. 3. Saldana, J. (2009). The coding manual for qualitative researchers. Los Angeles, CA: SAGE.
  • 42. Study Objective Our research team initiated the Viral Inhibition through Better reEntry (VIBE) Study to better understand: – frequency and causes of post-release interruptions in ART among HIV+ persons leaving jail in San Diego County, California.
  • 43. Methods Setting: San Diego County operates 7 jail facilities housing >5,000 inmates. HIV+ inmates treated by UCSD physicians; HIV+ inmates eligible for the County’s AIDS Case Management Program Recruitment: August 2010-October 2011 Eligibility: 1) 18+ years old 2) released from SD county jail in the last 30 days 3)not currently incarcerated 4) ever diagnosed with HIV 5) received HIV care during their last incarceration
  • 44. Methods (con.) Data Collection: Interviewer-administered quantitative survey and a 1-hour qualitative interview Data analysis: descriptive statistics, regression modeling to identify factors independently associated with ART discontinuity; qualitative interview summaries coded using descriptive coding 3,4 to identify references to ART discontinuity and its contributing factors 63 HIV+ recently-released individuals were enrolled in the study
  • 45. Results: ART Continuity After Jail Release Of the 38 participants on ART at the time of release 23 (61%) missed at least one dose immediately following their release (average number of days = 4)
  • 46. Days of missed ART doses immediately after jail release (N=38)
  • 47. Results (cont.): Survey results Most commonly cited reason for missed doses while in jail: need for HIV physician to prescribe medications after incarceration Other reasons: unavailability of participant’s full ART regimen, provision of incorrect drugs or dosages, not wanting to go to HIV clinic for fear of HIV+ identification
  • 48. Survey results: Reasons for missing ART doses after jail release (N=23) % Didn’t have the medications 87 Couldn’t pay for the medications 26 Was using drugs or alcohol 9 Had medications but couldn’t get to them when needed 4 Top priority for participants who missed ART doses immediately after release (N=23) % Get drug or alcohol treatment 35 Find housing 22 Get cash 17 Reunite with family, partner or friends 9 Take care of legal problems 4 Use drugs or alcohol 4 Get HIV care/medications 4 Get identification 4
  • 49. Comparing those who missed doses after jail release to those who did not: Missing ART doses was significantly associated with individuals who were younger, who used transportation from treatment facilities or used public transportation, and reported post-release methamphetamine use
  • 50. Results: In-depth interviews Barriers to post-release ART missed doses included: Expiration of MediCal and/or AIDS Drug Assistance Program (ADAP) coverage Logistical issues: medications not delivered to drug treatment facility, lack of transportation
  • 51. Conclusions A majority of VIBE Study participants missed ART doses immediately following jail release. Factors such as discontinued medical insurance played a role Participants reported competing priorities/demands: substance abuse treatment, housing, cash, etc.
  • 52. CQI Project at SDCJ Identifying needs of SDCJ – Many opportunities for improvements exist – Needs identified by administration Lack of HIV specialty care – Driven by concern for lawsuits – Disinterest by jail doctors to assume care of HIV inmates – Needs identified by consultant/care provider Improve HIV-related care at SDCJ – HAART initiation, management – Diagnose/manage HIV specific conditions including OIs – Post-exposure prophylaxis and HIV post-test counseling
  • 53. CQI Project at SDCJ Planning and implementing interventions (buy-in) to address needs – Not too difficult as long as interventions were “simple, cost-effective, and prevent lawsuits” Simple = minimal disruption to nursing staff and officers Cost-effective = not costing too much extra or breaking the budget Prevent complaints/lawsuits (unstated) – likely true though
  • 54. Administrative Obstacles Obstacle Intervention Outcome Provide consultation and Continued improvement 1. Lack of HIV specialty care direct HIV care of HIV care No intervention yet. No change, but lead by 2. Disinterest of physicians Consider more education example No intervention yet. No change, but lead by 3. Disinterest of nursing staff Consider more education example No intervention yet. No change, but lead by 4. Disinterest of officers Consider more education example Some education provided Some improvement of 5. Disinterest of pharmacists through direct interaction identification of errors No restriction on use of Perceived high costs of HIV Education of cost and HAART, but less difficulty 6. drugs (use of generic risk/benefit of HAART and w/obtaining resistance drugs?)/resistance testing resistance testing testing now
  • 55. HIV Medical Care Obstacles Obstacle Intervention Outcome Delay in initiating/resuming Usually started within a 1. None, seen by intake MD HAART few days, w/exceptions Weekly review of all HIV Less medication errors, 2. HIV medication errors meds for all SDCJ but disincentive for jail inmates staff to learn Inmates may refuse to 3. None No change come to clinic due to stigma Discharge inmates with HIV Discussion with nurses Variable and dependent 4. medications emphasizing importance on discharge RN & MD Work with transitional Improved transition of Inmates lost to followup on case managers to place care back with their HIV 5. discharge, high recidivism inmates in drug rehab primary care provider, rates programs/placement decreased recidivism Implemented VIBE study Identified gaps in the Transitional care upon 6. to look at transitional area of discharging release from jail care inmates with HIV meds
  • 56. Number of Inmates 0 5 10 15 20 25 30 35 40 45 1/15/2008 2/15/2008 3/15/2008 4/15/2008 5/15/2008 6/15/2008 7/15/2008 8/15/2008 9/15/2008 10/15/2008 11/15/2008 12/15/2008 1/15/2009 2/15/2009 3/15/2009 4/15/2009 5/15/2009 6/15/2009 7/15/2009 Week 8/15/2009 9/15/2009 10/15/2009 11/15/2009 12/15/2009 1/15/2010 2/15/2010 3/15/2010 4/15/2010 5/15/2010 6/15/2010 7/15/2010 HIV+ Inmates in San Diego County Jails 8/15/2010 9/15/2010 10/15/2010 11/15/2010 VDF FAC8 SDCJ LCDF GBDF EMDF Total #
  • 57. Number of Errors 0 1 2 3 4 1.5 2.5 3.5 4.5 0.5 1/15/2008 2/15/2008 3/15/2008 4/15/2008 5/15/2008 6/15/2008 7/15/2008 8/15/2008 9/15/2008 10/15/2008 11/15/2008 12/15/2008 1/15/2009 2/15/2009 3/15/2009 4/15/2009 5/15/2009 6/15/2009 7/15/2009 Week 8/15/2009 9/15/2009 10/15/2009 11/15/2009 12/15/2009 1/15/2010 2/15/2010 3/15/2010 4/15/2010 5/15/2010 6/15/2010 7/15/2010 ARV Prescription Errors in San Diego County Jails 8/15/2010 9/15/2010 10/15/2010 11/15/2010 Errors
  • 58. ARV Medication Errors Total of 86 errors over 126 weeks of ARV review – from 83 providers (37 unique providers) – 3 providers with 2 different errors Errors per week – Mean = 0.68 errors/week Range = 0-4 errors/week Errors per provider – Median = 1 error/week – Range = 1-9 errors – 16 providers with 2 or more errors
  • 59. ARV Medication Errors Type of Errors: 1 Less than 3 ARV drugs 30 2 Incorrect dose of ARV drug 37 3 Incorrect frequency of ARV drug 9 4 ARV interaction 1 5 MD error (ie. Zerit instead of Zestril) 5 6 Missing Ritonavir as a Booster PI 1 7 Missing PI with Ritonavir 1 8 Too many ARV agents 1 9 Written for same drug twice 1
  • 60. Summary and Future Directions Many opportunities exist for continued improvement in the delivery of quality HIV care in inmates at SDCJ – Has been successful in some areas – Require buy-in and support of administration and all those involved in care Future directions – Continue multi-pronged CQI projects – Continue providing education and developing rapport and collaborations with those interested in HIV care
  • 61. Acknowledgments Colleagues who have shared Emergency Department the burden of work at the jail Physicians – Chris Mathews – Ted Chan – Theo Katsivas – Gary Vilke – Alfredo Tiu – Tyler Lonergan SDCJ Staff Transitional Case Managers – Earl Goldstein – Rafaela Jennings – Sue Smith – Sonja Proctor – Terry Zakosky – Amy Applebaum – Chris McClean – Tim Smith SDCJ Pharmacy Staff VIBE Study Staff – Jeffrey Crutchfield – Robin Pollini – Ashley Clark – Mari Zuniga – Ida Bleich – Ken Saragosa – Serena Ruiz