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Presented to Dr. Waqas Kazmi
Presented by Hassan yousaf
Roll no: 20204022-014
Title: Results and Risk factors of thyroid
cancer
Department of MS Biological sciences
University of Sialkot.
Results and discussion
 Distribution of data on the base of different variables
 Case-control study was based on 160 cases and 160 controls.
 Study contains 88 male patients and 232 female patients.
 88 patients belong to rural areas and 232 belong to urban
areas.
 67 patients belong to age 15-35, and 63 belong to age 36-55.
Continue…
 30 belong to the age more than 56.
 87 were illiterate and 67 controls were literate, shows its
among illiterate people.
 58 cases belong to group of living sedentary life.
 83 cases have a family history of thyroid cancer.
 77 patients don’t have family history.
 82 cases used iodine diet and suffered from thyroid cancer,
while 78 controls did not intake iodine diet.
Continue…
 90 cases have the history of acromegaly disease.
 Surprisingly 98 patients had oxidative stress
 108 cases intake fats.
 of fast food are 91.
 of fried food are 108 patients.
 Patients who used vegetables are 151,
 of red meat are 110
 Of sea food are 124, and of goiter are 56.
Analytical analysis of result
 Binary logistic regression model
 Regression coefficients
 Odds ratio (for the significance of variables)
 P-value and CI (confidence interval)
 Adequacy of data ( omnibus test) and chi Square test.
 Hosmer and Lemeshow (for goodness of fit)
 75% data is adequate and 25% is misclassified.
Significant risk factors
 Family history of cancer (1.2 times)
 Use of iodine diet (2.6 times)
 Oxidative stress highest risk factor (6 times)
 Intake of read meat, fast food, fried food and fats intake (2.3
times)
 Sea food (2.3 times)

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DR. Waqas ppt.pptx

  • 1. Presented to Dr. Waqas Kazmi Presented by Hassan yousaf Roll no: 20204022-014 Title: Results and Risk factors of thyroid cancer Department of MS Biological sciences University of Sialkot.
  • 2. Results and discussion  Distribution of data on the base of different variables  Case-control study was based on 160 cases and 160 controls.  Study contains 88 male patients and 232 female patients.  88 patients belong to rural areas and 232 belong to urban areas.  67 patients belong to age 15-35, and 63 belong to age 36-55.
  • 3. Continue…  30 belong to the age more than 56.  87 were illiterate and 67 controls were literate, shows its among illiterate people.  58 cases belong to group of living sedentary life.  83 cases have a family history of thyroid cancer.  77 patients don’t have family history.  82 cases used iodine diet and suffered from thyroid cancer, while 78 controls did not intake iodine diet.
  • 4. Continue…  90 cases have the history of acromegaly disease.  Surprisingly 98 patients had oxidative stress  108 cases intake fats.  of fast food are 91.  of fried food are 108 patients.  Patients who used vegetables are 151,  of red meat are 110  Of sea food are 124, and of goiter are 56.
  • 5. Analytical analysis of result  Binary logistic regression model  Regression coefficients  Odds ratio (for the significance of variables)  P-value and CI (confidence interval)  Adequacy of data ( omnibus test) and chi Square test.  Hosmer and Lemeshow (for goodness of fit)  75% data is adequate and 25% is misclassified.
  • 6. Significant risk factors  Family history of cancer (1.2 times)  Use of iodine diet (2.6 times)  Oxidative stress highest risk factor (6 times)  Intake of read meat, fast food, fried food and fats intake (2.3 times)  Sea food (2.3 times)