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techniques of solubility
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It includes Introductory part about what is Dissolution...then Mechanism of Dissolution is elaborated...Theories of Dissolution also given..It also includes Factors affecting Dissolution profile..Along with References given below for easily searching..
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Superdisintegrants are developed to improve the palatability in orally administered products and to advancing the development of various formulations with increase performance and acceptability. Superdisintegrants are used to revise the potency of solid dosage form .This is accomplish by decreasing the disintegration time which in turn improvement the drug dissolution rate. Diverse categories of Superdisintegrants such as synthetic, semi synthetic, natural and cross processed blend etc. The present study comprises the various kinds of Superdisintegrants which are being used in formulations to provide the safer effective drug delivery with patient’s compliance. Snehal N. Dhoot | Sharda P. Shahane | Kiran. P. Gaikwad | Leena P. Joge | Jaya P. Ambhore "Superdisintegrants in Orally Administered Products of Pharmaceuticals: A Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-4 , June 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50282.pdf Paper URL: https://www.ijtsrd.com/pharmacy/pharmaceutics/50282/superdisintegrants-in-orally-administered-products-of-pharmaceuticals-a-review/snehal-n-dhoot
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Superdisintegrants are developed to improve the palatability in orally administered products and to advancing the development of various formulations with increase performance and acceptability. Superdisintegrants are used to revise the potency of solid dosage form .This is accomplish by decreasing the disintegration time which in turn improvement the drug dissolution rate. Diverse categories of Superdisintegrants such as synthetic, semi synthetic, natural and cross processed blend etc. The present study comprises the various kinds of Superdisintegrants which are being used in formulations to provide the safer effective drug delivery with patient’s compliance. Snehal N. Dhoot | Sharda P. Shahane | Kiran. P. Gaikwad | Leena P. Joge | Jaya P. Ambhore "Superdisintegrants in Orally Administered Products of Pharmaceuticals: A Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-4 , June 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50282.pdf Paper URL: https://www.ijtsrd.com/pharmacy/pharmaceutics/50282/superdisintegrants-in-orally-administered-products-of-pharmaceuticals-a-review/snehal-n-dhoot
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SOLUBILIZATION TECHNIQUES
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A Brief presentation on the topic- phase solubility analysis and pH solubility profile, which covers the following aspects: - Solubility introduction - importance of solubility - factors influencing solubility - Phase solubility analysis introduction - method of analysis - purification technique - introduction to pH solubility profile.
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Theories of solubulisation
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Process of solubilization
Step 1: Holes opens in the solvent Step2 : Molecules of the solid breaks away from the bulk Step 3:The freed solid molecule is integrated into the hole in the solvent
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