Cancer research

1. © 2009 VIRUN ® V I R U N ® dp technology targeted delivery with precision

2. Virun ® is a life science organization focused on improving life through safe and effective drug delivery. Our research strength comes from the ability to form partnerships and solve problems collectively. Virun’s multiple joint venture collaborations are composed of focused, driven and humanitarian ideologists with a benevolent research ethic and problem solving directive. © 2009 VIRUN ® V I R U N ® dp technology targeted delivery with precision

3. Virun ® focuses on targeting specific cells and cell receptors in the body. Tumors are composed of epithelial cells that can be penetrated by receptor mediated endocytosis or small particle manipulation. Binding siRNA to specific endocytic vehicles allow cell knockdown and reduce tumor proliferation. V I R U N ® dp technology targeted delivery with precision © 2009 VIRUN ® siRNA- dp

4. siRNA- dp siRNA is a silencing nucleic acid that can interfere with the proliferation of a tumor. The problem with siRNA is that it destabilizes before performing its primary function. Virun dp technology can target receptors to better increase the half life of siRNA to support cell knockdown. © 2009 VIRUN ® our body is an intricate system

5. delivering a drug is not a simple as the drug itself, there are many barriers that a drug must encounter before its final operation. combining the drug with different segments of intelligence allows these barriers to be penetrated. V I R U N ® dp technology targeted delivery with precision © 2009 VIRUN ®

6. procuring effectiveness… © 2009 VIRUN ® … strength in partnering

7. Virun, Inc. 21118 Commerce Pointe Dr. City of Industry, CA. 91789 (909) 839-0629 V I R U N ® dp technology targeted delivery with precision © 2009 VIRUN ® www. virun.com