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MALIGNANT TUMORS OF THE
BRAIN
VISITH DANTANARAYANA
GROUP 301
CANCEROUS TUMORS
• PRIMARY CORRESPONDS TO THE TUMORS
ORIGINATING IN THE BRAIN.
• SECONDARY CORRESPONDS TO THE
METASTASIS OF TUMORS INTO THE BRAIN.
PRIMARY SECONDARY
RADIOLOGICAL ARRAY
• BOTH PRIMARY AND SECONDARY CATEGORIES
COMPRISE MALIGNANT TUMORS.
• BUT RADIOLOGICALLY THEY HAVE CERTAIN CRITERIA,
CRUCIAL FOR THEIR DISTINGUISHED IDENTIFICATION.
• BOTH PRIMARY AND SECONDARY TUMORS ARE
HYPERDENSIVE MASSES.
• HOWEVER, PRIMARY TUMORS HAVE CLEAR UNEVEN
BORDERS WHEREAS THE SECONDARY ONES HAVE
CLEAR EVEN BORDERS, SO TO SPEAK.
• METASTATIC TUMORS USUALLY EMBOLDEN MORE
THAN ONE MALIGNANT PROCESS.
SEVERITY
POSSIBLE SYMPTOMS
• HEADACHE
• SEIZURES
• VOMITING
• AND EVENTUALLY SYNCOPE MAY DEVELOP
MALIGNANT AND BENIGN TUMORS
A MALIGNANT TUMOR WITH CEREBRAL
HAEMORRHAGE.
Along with traditional surgery and radiation, another effective therapy is
photodynamic therapy (PDT). By combining a photosynthesizer and a specific
light, PDT is able to be relatively selective and specific for certain types of
tumors. The benefits of PDT include:
- No negative interaction with other ongoing therapies
- Does not cause immuno-suppression (a weakening of the immune system)
- Not toxic
- Short treatment time, results in 48-72 hours.
GLIOBLASTOMA MULTIFORME
• GLIOBLASTOMA MULTIFORME IS THE MOST AGGRESSIVE
(GRADE IV) AND MOST COMMON FORM OF A MALIGNANT
BRAIN TUMOR.
• EVEN WHEN AGGRESSIVE MULTIMODALITY THERAPY
CONSISTING OF RADIOTHERAPY, CHEMOTHERAPY, AND
SURGICAL EXCISION IS USED, MEDIAN SURVIVAL IS ONLY 12–
17 MONTHS.
OLIGODENDROGLIOMA
A MALIGANT TYPE OF GLIOMA THAT ARE
BELIEVED TO ORIGINATE FROM THE
OLIGODENDROCYTES OF THE BRAIN OR FROM
PRECURSORS.
IMAGING AS THE MAIN MEANS OF
DIAGNOSIS
• INVASIVE METHODS –
PNEUMOENCEPHALOGRAPHY
• NON INVASIVE METHODS –
CT SCAN, AND MRI
THE INVASIVE PNEUMOENCEPHALOGRAPHY IS NOT IN USE DUE TO ITS HIGH INVASIVE
QUALITY REQUIRING THE DRAINAGE OF CSF FROM AROUND THE BRAIN AND INJECTING
AIR.
RADIOLOGICAL TREATMENTS
• GAMMA KNIFE RADIATION THERAPY
WHEN THE MALIGNANT TUMOR IS VIRTUALLY
INACCESSIBLE WITH THE AID OF A SCALPEL OR ANY
OTHER SURGICAL INSTRUMENT.
STEOTACTIC SURGERY
• MINIMAL INVASIVENESS
• ACCURATE FOR SMALL MALIGNANT TUMORS
DIAGNOSED AT AN EARLY STAGE.
THANK YOU

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Malignant tumors of the brain

  • 1. MALIGNANT TUMORS OF THE BRAIN VISITH DANTANARAYANA GROUP 301
  • 2.
  • 3. CANCEROUS TUMORS • PRIMARY CORRESPONDS TO THE TUMORS ORIGINATING IN THE BRAIN. • SECONDARY CORRESPONDS TO THE METASTASIS OF TUMORS INTO THE BRAIN. PRIMARY SECONDARY
  • 4. RADIOLOGICAL ARRAY • BOTH PRIMARY AND SECONDARY CATEGORIES COMPRISE MALIGNANT TUMORS. • BUT RADIOLOGICALLY THEY HAVE CERTAIN CRITERIA, CRUCIAL FOR THEIR DISTINGUISHED IDENTIFICATION. • BOTH PRIMARY AND SECONDARY TUMORS ARE HYPERDENSIVE MASSES. • HOWEVER, PRIMARY TUMORS HAVE CLEAR UNEVEN BORDERS WHEREAS THE SECONDARY ONES HAVE CLEAR EVEN BORDERS, SO TO SPEAK. • METASTATIC TUMORS USUALLY EMBOLDEN MORE THAN ONE MALIGNANT PROCESS.
  • 5.
  • 7. POSSIBLE SYMPTOMS • HEADACHE • SEIZURES • VOMITING • AND EVENTUALLY SYNCOPE MAY DEVELOP
  • 8. MALIGNANT AND BENIGN TUMORS A MALIGNANT TUMOR WITH CEREBRAL HAEMORRHAGE.
  • 9. Along with traditional surgery and radiation, another effective therapy is photodynamic therapy (PDT). By combining a photosynthesizer and a specific light, PDT is able to be relatively selective and specific for certain types of tumors. The benefits of PDT include: - No negative interaction with other ongoing therapies - Does not cause immuno-suppression (a weakening of the immune system) - Not toxic - Short treatment time, results in 48-72 hours.
  • 10. GLIOBLASTOMA MULTIFORME • GLIOBLASTOMA MULTIFORME IS THE MOST AGGRESSIVE (GRADE IV) AND MOST COMMON FORM OF A MALIGNANT BRAIN TUMOR. • EVEN WHEN AGGRESSIVE MULTIMODALITY THERAPY CONSISTING OF RADIOTHERAPY, CHEMOTHERAPY, AND SURGICAL EXCISION IS USED, MEDIAN SURVIVAL IS ONLY 12– 17 MONTHS.
  • 11. OLIGODENDROGLIOMA A MALIGANT TYPE OF GLIOMA THAT ARE BELIEVED TO ORIGINATE FROM THE OLIGODENDROCYTES OF THE BRAIN OR FROM PRECURSORS.
  • 12. IMAGING AS THE MAIN MEANS OF DIAGNOSIS • INVASIVE METHODS – PNEUMOENCEPHALOGRAPHY • NON INVASIVE METHODS – CT SCAN, AND MRI THE INVASIVE PNEUMOENCEPHALOGRAPHY IS NOT IN USE DUE TO ITS HIGH INVASIVE QUALITY REQUIRING THE DRAINAGE OF CSF FROM AROUND THE BRAIN AND INJECTING AIR.
  • 13.
  • 14. RADIOLOGICAL TREATMENTS • GAMMA KNIFE RADIATION THERAPY WHEN THE MALIGNANT TUMOR IS VIRTUALLY INACCESSIBLE WITH THE AID OF A SCALPEL OR ANY OTHER SURGICAL INSTRUMENT.
  • 15. STEOTACTIC SURGERY • MINIMAL INVASIVENESS • ACCURATE FOR SMALL MALIGNANT TUMORS DIAGNOSED AT AN EARLY STAGE.