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Chapter 14 Human Heredity
14-1 Human Heredity
[object Object],[object Object]
Human Chromosomes ,[object Object],[object Object]
Karyotype ,[object Object]
[object Object],[object Object],23 Diploid 46
Sex Chromosomes ,[object Object],[object Object],[object Object],[object Object]
Q: Why are males & females born in a roughly 50:50 ratio? ,[object Object],X X Y
 
Human Traits ,[object Object],[object Object]
Pedigree ,[object Object]
 
[object Object],[object Object],[object Object]
Polygenic Traits ,[object Object],[object Object]
The Human Genome ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Humans aren’t easy test subjects
Blood Group Genes ,[object Object],[object Object],[object Object],[object Object]
Q: How do scientists identify recessive alleles that cause these disorders ,[object Object]
PKU – phenylketonuria   ,[object Object],[object Object],[object Object],[object Object],[object Object]
PKU
Tay Sachs ,[object Object],[object Object],[object Object],[object Object]
Achondroplasia - dwarfism ,[object Object],[object Object],[object Object]
Huntington's ,[object Object],[object Object]
Huntington's affect on the brain
Codominant ,[object Object],[object Object]
From Gene to Molecule
Cystic Fibrosis (CF) ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Sickle Cell Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Q: Why do so many African Americans carry the sickle cell allele? ,[object Object],[object Object]
Where malaria is common Where sickle cell is common
Dominant or Recessive ,[object Object],[object Object],Dominant
 
14-2 Human Chromosomes
[object Object],[object Object],[object Object],[object Object]
Sex Linked Genes ,[object Object],[object Object],X
Colorblindness ,[object Object],[object Object],[object Object]
Q: Why the difference between the sexes? ,[object Object],[object Object],just one Two copies
Hemophilia ,[object Object],[object Object],[object Object],[object Object],Blood clotting
Duchenne Muscular Dystrophy ,[object Object],[object Object],[object Object],[object Object]
X-Chromosome Inactivation ,[object Object],[object Object],[object Object]
Calico Cats ,[object Object]
nondisjunction ,[object Object]
[object Object]
 
Down Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Down Syndrome
Turners Syndrome (female) ,[object Object],[object Object],[object Object]
 
Klinefelters Syndrome (males) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
14-3 Human Molecular Genetics
Human DNA Analysis ,[object Object],[object Object]
Testing for alleles ,[object Object],[object Object],[object Object],[object Object]
DNA fingerprinting ,[object Object],[object Object],[object Object]
The Human Genome Project ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Promoter ,[object Object],[object Object],[object Object]
A Breakthrough for Everyone ,[object Object],[object Object]
Gene Therapy ,[object Object]
Ethical Issues in Human Genetics ,[object Object],[object Object],[object Object]

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