This document contains 20 multiple choice questions testing knowledge of endocrinology for medical students. The questions cover topics like the hormones that stimulate insulin secretion, causes of diabetes mellitus, principles of dietary treatment for diabetes, features of Cushing's syndrome and how to test for it, features of hypo- and hyperparathyroidism, causes of hypercalcemia, features of hypo- and hyperthyroidism, causes of hypoglycemia, features of hypoglycemic coma, causes of polyuria and polydipsia, effects of sulfonylureas in diabetes treatment, hormones produced by the thyroid gland, features of diabetes mellitus, features of diabetic neuropathy, presenting features of hypothyroidism, and

1. End Lecture MCQ Test on Endocrinology for MBBS students
All are true/ false type questions Time: 01 hour
1.The secretion of Insulin is stimulated by
a) Sympathetic nerve stimulation
b) Glucagon
c) Dopamine
d) Somatostatin
e) Acetylcholine
2.Diabetes mellitus may occur as a secondary consequence of the following conditions
a) Chronic pancreatitis
b) Albinism
c) Acromegaly
d) Addison's disease
e) Haemochromatosls
3. Dietary treatment of diabetes mellitus should be guided by the following principles
a) Small frequent meals are more suitable than one or two large ones.
b) Foods with high fiber content should be avoided because they slow carbohydrate metabolism.
c) The carbohydrate content of the diet should provide about half of the total calorie intake.
d) Fat should not contribute more than 35% of total calorie intake.
e) Mono-unsaturated fatty acid should be excluded from the diet as far as possible.
4. The recognized features of Cushing's syndrome include
a) Growth spurt in children
b) Distal myopathy
c) Proximal sensory neuropathy
d) Loss of scalp hair
e) Bruising
5. Outpatient screening methods for confirming the presence Cushing's syndrome indude
a) Overnight dexamethazone test
b) 24 hours urinary free cortisol test
c) Insulin tolerance test
d) 48 hours low dexamthazone test
e) Random cortisol measurements
6. In the investigation of Cushings's syndrome
a) The measurements of free levels of plasma cortisol is the most commonly performed definitive
test.
b) The measurement of random morning cortisol levels is a useful diagnostic test.
c) Plasma ACTH assay is valuable in defining an adrenal cause
d) The dexamethasone suppression test has high sensitivity in the diagnoses of Cushing's syndrome
e) Hyperkalaemia is a frequent finding
7. The following are recognized features of hypoparathyroidism
a) Cataracts
b) Convulsions
c) Intracranial calcification

2. d) Papilloedema
e) Osteitis fibrosa cystica
8. The following are recognized features of primary hyperparathyroidism
a) Renal colic
b) Shortened metacarpals
c) Polyuria
d) Constipation
e) Hyperchloraemic acidosis
9. In the differential diagnosis of hypercalcaemia the following should be considered
a) Secondary hyperparathyroidism
b) Pseudohypoparathyroidism
c) Vitamin D intoxication
d) Paget's disease
e) Addison's disease
10. The following could be features of hypothyroidism
a) Hypercarotenaemia
b) Proximal myopathy
c) Pretibial myxoedoma
d) An association with pernicious anemia
e) Raised serum triglyceride concentration
11. In thyrotoxicosis
a) Serum thyroxine(T4) concentration may be normal
b) When it occurs as a symptom of Grave's disease a high serum TSH level is responsible for thyroid
activity
c) The patient may be lethargic & depressed
d) Palmar erythema could be a feature
e) Onycholysis may occur
12. Hypoglycemia may occur as a result of
a) Previous gastric surgery
b) Diabetes mellitus in its early stages before diagnosis
c) Glycogen storage diseases
d) Acquired liver disease
e) Addison's disease
13- Recognized features of hypoglycemic coma include
a) Bradycardia
b) Sweating
c) Hyperventilation
d) Extensor plantar response
e) Convulsions
14. Polyuria and polydypsia occur in
a) Acute glomerular nephritis
b) Hysterical polydipsia
c) Hyperkalaemla
d) Hypocalcemia

3. e) Intracranial sarcoidosis before diagnosis
15. Following are true of sulphonylureas in diabetes mellitus
a) They can be used as an alternative if the requirement of insulin is more than 75units/day
b) Produce hyponatraemia
c) Can be used following pancreatectomy
d) Are more likely to cause hypoglycemia than biguanides
e) May cause peripheral insulin resistance
16. The thyroid gland produces the following hormones
a) Thyroglobulin
b) Tetra-iodothyronine
c) Tri-iodothyronine
d) Mono-iodothyronine
e) Calcitonin
17. Following are recognized features of diabetes mellitus
a) Pyoderma gangrenosum
b) Erysipelas
c) Recurrent boils
d) Symptomatic candidiasis
e) Lipo-atrophy
18. Recognized features of diabetic neuropathy include
a) Impotence
b) Diplopia
c) Muscle wasting
d) Myotonia
e) Loss of vibration perception in the legs
19. Presenting features of hypothyroidism include
a) Deafness
b) Menorrhagia
c) Hirsuitism
d) Enlarged thyroid gland
e) Osteoporosis
20. The following endocrine diseases could cause hyperpigmentation
a) Addisons
b) Diabetes mellitus type 2
c) Hypoparathyroidism
d) Hyperparathyroidism
e) Cushing's syndrome