2. Contents
1. Introduction
2. History of CR
3. How Does Computed Radiography Work ?
4. Image Generation of Computed Radiography
5. Advantages and Disadvantages of Computed Radiography
3. 1. Introduction
• Computed radiography is emerging as a digital imaging modality for use in
conventional radiography. It is based on photostimulable phosphor image
plate technology. The image plate (IP) is housed in a cassette similar to a
standard radiographic cassette. The IP phosphor retains a latent image of the
energy pattern to which it was exposed. This latent image is "read" as it is
released from the phosphor by laser light exposure.
4. 1. Introduction
• The image plates have a detective layer of
photostimulable crystals that contain different
halogenides such as bromide, chlorine, or iodine (eg,
BaFBr:Eu2+)
• Phosphor crystals are cast into plates of resin
material in unstructured scintillators.
• Image plates replace the conventional films in the
cassette.
• Exposure process with storage-phosphor image
plates:
5. 2. History of CR
The fundamental innovation in the
development of CR was by Kodak
(Luckey 1975) who conceived the
storage of an x-ray image in a
phosphor screen.
It required significant technical steps
and conceptualization of the
application by Fuji (Kotera et al
1980) to produce the first medical x-
ray images. Fuji, the main developer
of CR in the eighties, used
BaFBr:Eu2+ phosphor and a
cassette-based approach.
6. 3. How Does CR Systems Works ?
Image plate is
exposed to X-ray
energy
The image plate is
scanned with a
laser beam.
The stored energy
is set free and light
is emitted.
An array of
photomultipliers
collects the light.
Light is converted
to electrical charges
by an analog-to
digital converter
8. 4. Image Generation and Processing of CR
Protective layer:
• A very thin, tough, clear plastic for protection
of the phosphor layer
Phosphor, or active, layer :
• A layer of photostimulable phosphor that
“traps” electrons during exposure
• Usually made of phosphors from the barium
fluorohalide
• May also contain a dye that differentially
absorbs the stimulating laser light to prevent as
much spread as possible
Image Plate Modeling
9. 4. Image Generation and Processing of CR
Reflective layer:
• A layer that sends light in a forward
direction when released in the cassette
reader
• May be black to reduce the spread of
stimulating light and the escape of
emitted light
• Some detail lost in this process
Conductive layer:
• A layer of material that will absorb and
reduce static electricity
Color layer:
• Newer plates may contain a color layer,
located between the active layer and the
support that absorbs the stimulating light
but reflects emitted light.
Support layer:
• A semi-rigid material that gives the
imaging sheet some strength.
Backing layer: A soft polymer that
protects the back of the cassette.
10. 4. Image Generation and Processing of CR
X-Ray
Electron
Trap
ABSORPTION
Electron
Trap
EMISSION
Laser Stimulation
light
• Image plates exposed by
conventional X-ray
equipment.
• Eu+2 Eu+3 + e-
• Electrons are trapped in F-
centre
• Latent image generated as a
matrix of trapped electrons
in the plate.
Conduction band
Valenced band
11. An energy diagram of the excitation and PSL
processes in a BaFBr:Eu2+ phosphor
12. 4. Image Generation and Processing of CR
Read-out Process by Scanner
• The extracted imaging plate is scanned with
red laser and gives energy to trapped electron
and energizes them.
• Extra energy allows the trapped energy to
escape active layer where they emit blue light
at energy of 3eV.
• Laser scans IP multiple times.
• Scanning produces lines of light intensity
information that are detected by
photomultiplier tube that amplifies and send it
to digitizer.
13. 4. Image Generation and Processing of CR
In the process of digitizing the light signal, each phosphor storage center is scanned .
The light is directed to the photomultiplier/charged coupled device that converts the light to an
electronic signal.
That electronic signal is digitized by an analog to digital converter (ADC).
The ADC assigns each picture element or pixel a value that corresponds to a level of brightness.
The entire image is divided into matrix of pixels based on the brightness of each pixel.
Number of photons detected determine the gray level.
Each pixel can have a gray level between 2 and 4096.
Digitizing the Signal
14. 4. Image Generation and Processing of CR
• Spatial resolution
Dependent on IP size
Less than corresponding speed screen-film
• Contrast sensitivity
Dependent on exposure and SNR
• Exposure
Variable speed detector
Image Performance Measures
15. 4. Image Generation and Processing of CR
• Not all electrons have came back to the initial phase after reading.
• Exposure to a bright fluorescent light removes the remaining information in 10-
15 sec and the IP is reinserted into the cassette for reuse.
• Ghosting may appear in the IP if the residual latent image remained so it should
be removed by flooding with intense white light.
Erasing
16. 5.Advantages and Disadvantages of CR
systems
Advantages of CR systems
• Reduced rates of failed x-ray exposure.
• Because CR systems are cassette based, they can
easily be integrated into existing radiographic
devices, are highly mobile, and are easy to use for
bedside examinations and immobile patients.
• Flexible in routine clinical use.
• Can easily be replaced by the radiographer with no
need for specialized equipment or service personnel
if a single image plates shows defects.
• Imaging plates are reusable.
Disadvantage of CR systems
• Spatial resolution is usually lower than that with
conventional screen-film combinations.
• Long time to view image.
• Risk of over-exposure.
• High maintenance.
Notas del editor
• Computed radiography (CR), also commonly known as Photostimulable phosphor (PSP) imaging, employs reusable imaging plates and associated hardware and software to acquire and to display digital projection radiographs. • It involves the PSP plate detector handling between two sequential stages of exposure and data acquisition. • Imaging plate in a cassette must be processed in CR reader after X-ray exposure for conversion to digital images in raster pattern.
Bilgisayarlı radyografi sistemleri Bromid(Br),Klorin(Cl) ve iyodin(I) gibi farklı halojenleri içeren foton uyarmalı kristaller tabakasına sahiptir. Foton uyarmalı kristaller özel kristaller içerisine (Genelde üreticiler BaFX:Eu+2 (Baryum Florohalid)kristalini kullanırlar. X burada klorin(Cl),Bromid(Br),İyodin(I) veya bunların karışımları olabilir.)fosfor kristallerinin tanecikler şeklinde rastgele katkılanmasıyla elde edilirler. CR sistemlerde sırasıyla x-ışını jeneratörü ve hastadan gelen x-ışınları görüntü kaydedici fosfor plakaya yönlendirilirler. X-ışınları plakadaki kristallerin elektronlarının bir üst seviyeye uyarılmalarını sağlar. Kristale gelen x-ışınları Eu+2 iyotlarıyla etkileşerek Eu+3 iyonları oluşumunu sağlar. Bu olay sonucu meydana gelen hareketli serbest elektronlar F merkezlerinde tuzaklanır ve yarı kararlı tabakada tutulmuş olur. Böylece x-ışını enerjileri plakada kaydedilmiş olur. Bu depolanan enerji kristallerin özelliğine göre 4-5 saat kayıtlı tutulabilir. Ama farklı soğrulma bölgelerindeki enerji farklılıklarının kaybolmaması için okuma işlemi hemen yapılmalı ve kristal fazla bekletilmemelidir.Işınlama sırasında değerlik bandındaki elektronlar iletkenlik bandına uyarılır. Çoğu elektronlar hareket halindeyken F merkezlerinde tuzaklanırlar. Okuma işleminde görüntü kaydedici plakalar yüksek enerjili lazerle(kırmızı ışık) nokta nokta taranır. F merkezlerine gelen kırmızı ışık burada tuzaklanan elektronu iletim bandına geçirir. İletim bandına geçen elektronlar Eu+3 iyonları tarafından tutulur ve Eu+2 oluşumunu sağlar serbest elektronların fazla enerjisi ise mavi-yeşil ışık(~700nm) olarak yayınlanır. Bu ışınlar fotoçoğaltıcı tüpe yönlendirilir. Burada kırmızı lazer ışığının tüpe girmesi filtrelerle engellenir. Işık enerjisi elektrona ve elektrik sinyaline çevrilir. Sonra bu sinyal sayısallaştırılır.
Modern computed tomography, using storage phosphor imaging plates, can be traced to 1973, when George Luckey, a research scientist at Eastman Kodak Company, filed a patent application titled Apparatus and Method for Producing Images Corresponding to Patterns of High Energy Radiation. His abstract states, « A temporary storage medium, such as an infrared-stimulable phosphor or thermoluminescent material, is exposed to an incident pattern of high energy radiation. A time interval after exposure, a small area beam of long wavelength radiation or heat scans the screen to release the stored energy as light. An appropriate sensor receives the light emitted by the screen and produces electrical energy in accordance with the light received.»
In 1975, when George’s patent(US 3,859,527) was approved, Kodak also patented the first scanned storage phosphor system, thus giving birth to modern computed radiography.
During the 1980’s, a rash of patents followed that referenced George’s nnow-legendary invention. While Fuji was the first to actually commercialize a complete CR system(1983), many other companies also filed patents that referenced George’s: 3M, Agfa, Fujistu, Siemens, Toshiba, and of course, more from Kodak.
In computed radiography, when imaging plates are exposed to X-rays or gamma rays, the energy of the incoming radiation is stored in a special phosphor layer. A specialized machine known as a scanner is then used to read out the latent image from the plate by stimulating it with a very finely focused laser beam. When stimulated, the plate emits blue light with intensity proportional to the amount of radiation received during the exposure. The light is then detected by a highly sensitive analog device known as a photomultiplier (PMT) and converted to a digital signal using an analog-to-digital converter (ADC). The generated digital X-ray image can then be viewed on a computer monitor and evaluated. After an imaging plate is read, it is erased by a high-intensity light source and can immediately be re-used - imaging plates can typically be used up to 1000 times or more depending on the application.
Protective layer:
A very thin, tough, clear plastic for protection of the phosphor layer
Phosphor, or active, layer :
A layer of photostimulable phosphor that “traps” electrons during exposure
Usually made of phosphors from the barium fluorohalide
May also contain a dye that differentially absorbs the stimulating laser light to prevent as much spread as possible
Reflective layer:
A layer that sends light in a forward direction when released in the cassette reader
May be black to reduce the spread of stimulating light and the escape of emitted light
Some detail lost in this process
Color layer:
Newer plates may contain a color layer, located between the active layer and the support that absorbs the stimulating light but reflects emitted light.
Support layer:
A semi-rigid material that gives the imaging sheet some strength.
Backing layer: A soft polymer that protects the back of the cassette.
Conductive layer:
A layer of material that will absorb and reduce static electricity
Action of X-ray exposure • When the X-ray is absorbed by the material, absorbed energy excites the europium atoms, causing ionization of Eu atom.
• Eu+2 Eu+3 + e-
• The electrons are raised to higher energy state in the conduction band. Once in the conduction band, electrons travel freely until they are trapped in a so called F-centre in a metastable state with an energy level slightly below that of conduction band but higher than that of the valence band.
Trapped electrons
• The number of trapped electrons per unit area is proportional to intensity of X-rays incident at each location. These trapped electrons constitute the latent image.
• Due to the thermal motion the trapped electrons will slowly be liberated from the traps, and so at room temperature the image should, however, be readable up to 8 hours after exposure.
Released light is captured by a PMT (photo multiplier tube)
This light is sent as a digital signal to the computer
The intensity (brightness) of the light – correlates to the density on the image
The cassette is placed in the reader where the IP is extracted and raster- scanned with a highly focused and intense laser light of low energy (~2 eV). • Laser light is absorbed at the F-center(Farbzentren center) and, thus, stimulates the trapped electrons up to conduction band where they are free to move to Europium atom thereby leaving high energy conduction band to lower energy valence band. • When these electrons become reabsorbed by trivalent Europium, trivalent Europium is transferred back into divalent Europium atom. This involves the liberation of high energy (~3 eV) and this is done by emission of green light. • Eu+2 Eu+3 + e-
With CR systems, no chemical processor or darkroom is necessary.
-Cassette is fed into a reader:
-Removes the imaging plate
-Scans it with a laser, releasing the stored electrons
THE LASER
-Light Amplification by Stimulated Emission of Radiation.
-Laser creates and amplifies a narrow, intense beam of coherent light.
-Laser requires a constant power source to prevent output fluctuations.
-Laser beam passes through beam-shaping optics to an optical mirror, which directs the laser beam to the surface of the imaging plate.
Reader scans the plate with red light in a zigzag, or raster, pattern.
• Laser gives energy to the trapped electrons.
• Red laser light is emitted at approximately 2 eV, which is necessary to energize the trapped electrons.
• Extra energy allows the trapped electrons to escape the active layer, where they emit visible blue light at an energy of 3 eV as they relax into lower energy levels.
USING THE LASER TO READ THE IMAGING PLATE
The light collection optics direct the released phosphor energy to an optical filter and then to the photodetector(photomultiplier tube).
Although there will be variances between manufacturers, the typical throughput is 50 cassettes per hour.
Some manufacturers claim up to 150 cassettes per hour, but based on average hospital department workflow, 50 cassettes per hour is much more realistic
In the process of digitizing the light signal, each phosphor storage center is scanned .
The light is directed to the photomultiplier/charged coupled device that converts the light to an electronic signal.
That electronic signal is digitized by an analog to digital converter (ADC).
The ADC assigns each picture element or pixel a value that corresponds to a level of brightness.
The entire image is divided into matrix of pixels based on the brightness of each pixel. Each square is called a pixel or picture element.
The typical number of pixels in a matrix range from about 512 × 512 to 1024 × 1024 and can be as large as 2500 × 2500.
As the number of pixels in a matrix increase for the same field of view, the smaller the pixels have to be to fit into that area; the smaller the pixels, the greater the spatial resolution.
The image is digitized by position (spatial location) and by intensity (gray level).
Each pixel contains bits of information, and the gray level is determined by how many photons struck the imaging plate in that particular location.
Bit depth: The number of bits per pixel.
The bit depth will be a factor in determining the quality of the image. A bit value of 21 or one (1) represents a black and white image. The larger the bit depth, the more shades of gray possible. The more shades of gray, the more detail the image can display. Each pixel can have a gray level between 2 (21) and 4096 (212).