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White Paper | CARESTREAM Bone Suppression Software
Bone Suppression for Chest Radiographic Images
Introduction
Chest radiography remains the most commonly used method
for screening and diagnosing lung diseases, such as lung
cancer, pneumothorax, interstitial disease, emphysema and
many others. The detectability of a lung disease on a chest
radiograph is affected by the signal-to-noise ratio (SNR) in the
image. High-contrast bone structures are major noise
contributors that significantly reduce the SNR in chest
radiographic images. A signal of interest in a chest radiograph
could be either partially or completely obscured, or
“overshadowed,” by the highly contrasted bone structures
surrounding it. This is why removing the bone structures,
especially the posterior rib and clavicle structures, is highly
desirable to increase the visibility of soft tissue.
Advanced X-ray imaging techniques, such as 3D imaging (CT
and tomosynthesis) and dual-energy subtraction, have been
developed to remove the overlapping bone-structure noise to
improve the visibility of soft tissue. However, these advanced
imaging technologies cannot replace the role of chest
radiography for its efficiency, low radiation dose, low cost, and
most particularly, its portability and mobility. Chest
radiography plays an essential role for patients in intensive care
units (ICUs). Advanced imaging techniques have not been
optimized for the use in ICUs where device portability and
mobility are required or highly desired.
Carestream’s Bone Suppression Software offers a solution to
suppress bone structures, including posterior ribs and clavicles,
in conventional and portable chest X-ray images. The solution
requires no additional procedure or radiation dose. The
software processes the chest radiographic images using
machine-learning and pattern-recognition technologies to
accurately detect the rib and clavicle structures and estimate
the structure profiles used in the subsequent suppression step.
This bone-suppression process is limited to the detected
structures to keep unnecessary changes to the original images
at minimal levels. The software is designed to suppress the
high-contrast bone structures while maintaining the integrity
of image quality, in particular the contrast-detail level, as
closely as possible to that of the original images.
CARESTREAM Bone Suppression Software
The CARESTREAM Bone Suppression Software takes in an
input image from a capture device (DR or CR) and processes
the image in the steps as shown in Figure 1. The image
processing includes five major steps: 1) lung segmentation,
2) rib and clavicle structure detection, 3) rib and clavicle edge
detection, 4) rib and clavicle profile estimation, and
5) suppression based on the estimated profiles. The bone-
suppression software outputs an image that suppresses both
the posterior rib and clavicle structures. The suppressed image
is then enhanced the same way as the original image for
visualization, and used as a companion view.
Image examples shown in Figure 2 illustrate some of the steps
for rib suppression. The rib detection is performed within the
segmented lung field. The detected ribs in Figure 2(c) are
further processed to accurately detect the rib edges. Rib
profiles are estimated for the detected ribs and used in the
subsequent suppression process. The suppression process is
limited to the rib areas only; areas outside of the ribs are not
affected. In addition, the rib edges are sufficiently suppressed
as shown in Figure 2(d). No additional image processing, in
particular, any smoothing operation, is performed to reduce
the image sharpness. It’s critical to maintain the image quality
(i.e., the contrast-detail level) of bone-suppressed images as
closely as possible to that of the original images so that both
larger, low-contrast abnormalities (as shown in Figure 4) and
subtle line structures (a pneumothorax, as shown in Figure 3)
can benefit from the suppression of bone structure noise with
improved detectability.
In the image-enhancement step, the standard CARESTREAM
DirectView EVP Plus Software is used to produce the rib-
suppressed companion view. The rib-suppressed images,
however, can be further refined by other Carestream image-
processing software, e.g., pneumothorax visualization
enhancement (CARESTREAM Pneumothorax Visualization
Software), as shown in the example in Figure 3(c).
White Paper | CARESTREAM Bone Suppression Software
2
(a) (b)
(c) (d)
Input DR or CR
chest images
Lung segmentation Rib/clavicle
detection
Rib/clavicle edge
detection
Bone profile
estimation
Rib/clavicle
suppression
Image
enhancement
Output
companion view
Figure 1: Image-processing chain to generate a bone-suppressed companion view
Figure 2: a) An input CR portable chest radiographic image; b) the image with segmented lung field; c) the image
with detected ribs; and d) the image with ribs suppressed.
White Paper | CARESTREAM Bone Suppression Software
3
Figure 3 shows a portable CR image with a pneumothorax in the upper right lung and its rib-suppressed companion view. The rib-
suppressed image is further processed using the CARESTREAM Pneumothorax Visualization Software. A region containing the
pneumothorax is selected from each of the three images. As Figure 3(d) shows, the contrast detail is well-preserved in the rib-
suppressed images for visualizing the signs of the subtle pneumothorax, i.e., the edge of the collapsed lung and the difference in
the texture between the regions separated by the edge.
Figure 4 shows a DR image with a large abnormality, confirmed by CT images, behind the right clavicle and the top rib. As shown
in Figure 4(b), the shape and size of the abnormality are much easier to see after suppression of the clavicle and rib. This
demonstrates that the software estimates the bone-structure profiles accurately and doesn’t over-suppress areas where a large
structure or abnormality presents.
(a) (b)
(c)
(d)
Figure 3: A portable CR chest image before (a) and after bone suppression (b). An enhanced image (c) generated using the
CARESTREAM Pneumothorax Visualization Software. Regions of interest (d) feature a pneumothorax from the upper right
lung, demonstrating that the contrast detail is well-preserved after rib suppression.
White Paper | CARESTREAM Bone Suppression Software
4
(a) (b)
(c) (d)
Figure 4: A conventional DR chest image (a) and its rib-suppressed companion view (b). CT images (coronal and
sagittal views) from the same patient. Arrows indicate the same large abnormalities.
White Paper | CARESTREAM Bone Suppression Software
www.carestream.com
© Carestream Health, Inc., 2014. CARESTREAM is a trademark of
Carestream Health. CAT 200 0039 1/14
Summary
Clearly, the interpretation of chest radiographs is very
challenging. The appearances or characteristics of various lung
diseases vary dramatically in terms of their size, shape and
contrast. It’s critical that a bone-suppression solution is capable
of preserving the image details so that the SNR can be
improved for a range of lung diseases after bone suppression.
We expect the software to provide radiologists and clinicians in
ICUs with an important tool to enhance their overall
interpretations of chest radiographs with improved
effectiveness and efficiency.

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Bone Suppression for Chest Radiographic Images

  • 1. White Paper | CARESTREAM Bone Suppression Software Bone Suppression for Chest Radiographic Images Introduction Chest radiography remains the most commonly used method for screening and diagnosing lung diseases, such as lung cancer, pneumothorax, interstitial disease, emphysema and many others. The detectability of a lung disease on a chest radiograph is affected by the signal-to-noise ratio (SNR) in the image. High-contrast bone structures are major noise contributors that significantly reduce the SNR in chest radiographic images. A signal of interest in a chest radiograph could be either partially or completely obscured, or “overshadowed,” by the highly contrasted bone structures surrounding it. This is why removing the bone structures, especially the posterior rib and clavicle structures, is highly desirable to increase the visibility of soft tissue. Advanced X-ray imaging techniques, such as 3D imaging (CT and tomosynthesis) and dual-energy subtraction, have been developed to remove the overlapping bone-structure noise to improve the visibility of soft tissue. However, these advanced imaging technologies cannot replace the role of chest radiography for its efficiency, low radiation dose, low cost, and most particularly, its portability and mobility. Chest radiography plays an essential role for patients in intensive care units (ICUs). Advanced imaging techniques have not been optimized for the use in ICUs where device portability and mobility are required or highly desired. Carestream’s Bone Suppression Software offers a solution to suppress bone structures, including posterior ribs and clavicles, in conventional and portable chest X-ray images. The solution requires no additional procedure or radiation dose. The software processes the chest radiographic images using machine-learning and pattern-recognition technologies to accurately detect the rib and clavicle structures and estimate the structure profiles used in the subsequent suppression step. This bone-suppression process is limited to the detected structures to keep unnecessary changes to the original images at minimal levels. The software is designed to suppress the high-contrast bone structures while maintaining the integrity of image quality, in particular the contrast-detail level, as closely as possible to that of the original images. CARESTREAM Bone Suppression Software The CARESTREAM Bone Suppression Software takes in an input image from a capture device (DR or CR) and processes the image in the steps as shown in Figure 1. The image processing includes five major steps: 1) lung segmentation, 2) rib and clavicle structure detection, 3) rib and clavicle edge detection, 4) rib and clavicle profile estimation, and 5) suppression based on the estimated profiles. The bone- suppression software outputs an image that suppresses both the posterior rib and clavicle structures. The suppressed image is then enhanced the same way as the original image for visualization, and used as a companion view. Image examples shown in Figure 2 illustrate some of the steps for rib suppression. The rib detection is performed within the segmented lung field. The detected ribs in Figure 2(c) are further processed to accurately detect the rib edges. Rib profiles are estimated for the detected ribs and used in the subsequent suppression process. The suppression process is limited to the rib areas only; areas outside of the ribs are not affected. In addition, the rib edges are sufficiently suppressed as shown in Figure 2(d). No additional image processing, in particular, any smoothing operation, is performed to reduce the image sharpness. It’s critical to maintain the image quality (i.e., the contrast-detail level) of bone-suppressed images as closely as possible to that of the original images so that both larger, low-contrast abnormalities (as shown in Figure 4) and subtle line structures (a pneumothorax, as shown in Figure 3) can benefit from the suppression of bone structure noise with improved detectability. In the image-enhancement step, the standard CARESTREAM DirectView EVP Plus Software is used to produce the rib- suppressed companion view. The rib-suppressed images, however, can be further refined by other Carestream image- processing software, e.g., pneumothorax visualization enhancement (CARESTREAM Pneumothorax Visualization Software), as shown in the example in Figure 3(c).
  • 2. White Paper | CARESTREAM Bone Suppression Software 2 (a) (b) (c) (d) Input DR or CR chest images Lung segmentation Rib/clavicle detection Rib/clavicle edge detection Bone profile estimation Rib/clavicle suppression Image enhancement Output companion view Figure 1: Image-processing chain to generate a bone-suppressed companion view Figure 2: a) An input CR portable chest radiographic image; b) the image with segmented lung field; c) the image with detected ribs; and d) the image with ribs suppressed.
  • 3. White Paper | CARESTREAM Bone Suppression Software 3 Figure 3 shows a portable CR image with a pneumothorax in the upper right lung and its rib-suppressed companion view. The rib- suppressed image is further processed using the CARESTREAM Pneumothorax Visualization Software. A region containing the pneumothorax is selected from each of the three images. As Figure 3(d) shows, the contrast detail is well-preserved in the rib- suppressed images for visualizing the signs of the subtle pneumothorax, i.e., the edge of the collapsed lung and the difference in the texture between the regions separated by the edge. Figure 4 shows a DR image with a large abnormality, confirmed by CT images, behind the right clavicle and the top rib. As shown in Figure 4(b), the shape and size of the abnormality are much easier to see after suppression of the clavicle and rib. This demonstrates that the software estimates the bone-structure profiles accurately and doesn’t over-suppress areas where a large structure or abnormality presents. (a) (b) (c) (d) Figure 3: A portable CR chest image before (a) and after bone suppression (b). An enhanced image (c) generated using the CARESTREAM Pneumothorax Visualization Software. Regions of interest (d) feature a pneumothorax from the upper right lung, demonstrating that the contrast detail is well-preserved after rib suppression.
  • 4. White Paper | CARESTREAM Bone Suppression Software 4 (a) (b) (c) (d) Figure 4: A conventional DR chest image (a) and its rib-suppressed companion view (b). CT images (coronal and sagittal views) from the same patient. Arrows indicate the same large abnormalities.
  • 5. White Paper | CARESTREAM Bone Suppression Software www.carestream.com © Carestream Health, Inc., 2014. CARESTREAM is a trademark of Carestream Health. CAT 200 0039 1/14 Summary Clearly, the interpretation of chest radiographs is very challenging. The appearances or characteristics of various lung diseases vary dramatically in terms of their size, shape and contrast. It’s critical that a bone-suppression solution is capable of preserving the image details so that the SNR can be improved for a range of lung diseases after bone suppression. We expect the software to provide radiologists and clinicians in ICUs with an important tool to enhance their overall interpretations of chest radiographs with improved effectiveness and efficiency.