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An Interesting case of Quadriparesis S.Karthikeyan., M4 Prof.P.Vijayaraghavan`s unit
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[object Object],[object Object],[object Object],Artery Right Left Carotid +  + Radial -- -- Brachial -- -- Femoral + + Popliteal + + Dorsalis pedis + +
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Superficial reflexes R L corneal + + conjunctival + + gag + + palatal + + abdominal + + cremastric + + plantar flexor flexor
DTRs R L biceps + + triceps + + supinator + + knee + + ankle + +
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
 
Investigations  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
INITIAL TREATMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],DAY 25/5 26/5 28/5 30/5  Sr.K 1.9 3.2 3.2 3.4
 
Urine analysis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ABG ,[object Object],[object Object],[object Object]
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Next step… ,[object Object],[object Object]
IMAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],R L Upper pole 0.94 0.68 Mid pole 0.90 0.64 Lower pole 0.78 0.64
Ct angiogram
 
 
 
 
 
Report  ,[object Object],[object Object],[object Object]
[object Object]
POSSIBILITIES ARE…………. DISEASE TYPE ENTITIES RHEUMATIC GIANT CELL arteritis,Cogan syndrome,Relapsing polychondritis,Ankylosing spondylitis,Rheumatoid arthritis,SLE,buerger`s disease INFECTIOUS Syphilis,TB OTHERS Atherosclerosis,ergotism,radiation induced damage,sarcoidosis,marfan syndrome,Ehler Danlos syndrome ,congenital co arctation of aorta
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Queries??????? ,[object Object],[object Object]
Takayasu's arteritis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogenesis  ,[object Object],[object Object],[object Object],[object Object]
Symptoms  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1990 Criteria of American College of Rheumatology for the Classification of Takayasu Arteritis  Criteria  Definition  Age at disease onset in year  Development of symptoms or findings related to Takayasu arteritis at age <40 years.  Claudication of extremities  Development and worsening of fatigue and discomfort in muscles of one or more extremity while in use, especially the upper extremities.  Decreased brachial artery pulse Decreased pulsation of one or both the brachial arteries BP difference >10mmHg Difference of >10mmHg in systolic blood pressure between arms  Bruit over subclavian arteries or aorta Bruit audible on auscultation over one or both subclavian arteries or abdominal aorta Arteriogram abnormality  Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal uppper or lower extremities, not due arteriosclerosis, fibro-muscular dysplasia, or similar causes: changes usually focal or segmental  For purposes of classification, a patient shall be said to have Takayasu's arteritis if at least three of these six criteria are present. The presence of any three or more criteria yields a sensitivity of 90.5% and a specificity of 97.8%. BP = blood pressure (systolic) difference between arms
TYPES TYPES 1 Aortic arch and branches 2 Abdominal aorta 3 Both arch and abdominal aorta 4 Pulmonary artery
Treatment  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
PROGNOSIS ,[object Object],[object Object],[object Object],[object Object]
Carry home points…….. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References  ,[object Object],[object Object],[object Object],[object Object],[object Object]
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Unusual Presentation of Takayasu Arteritis

  • 1. An Interesting case of Quadriparesis S.Karthikeyan., M4 Prof.P.Vijayaraghavan`s unit
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  • 11. Superficial reflexes R L corneal + + conjunctival + + gag + + palatal + + abdominal + + cremastric + + plantar flexor flexor
  • 12. DTRs R L biceps + + triceps + + supinator + + knee + + ankle + +
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  • 34. POSSIBILITIES ARE…………. DISEASE TYPE ENTITIES RHEUMATIC GIANT CELL arteritis,Cogan syndrome,Relapsing polychondritis,Ankylosing spondylitis,Rheumatoid arthritis,SLE,buerger`s disease INFECTIOUS Syphilis,TB OTHERS Atherosclerosis,ergotism,radiation induced damage,sarcoidosis,marfan syndrome,Ehler Danlos syndrome ,congenital co arctation of aorta
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  • 41. 1990 Criteria of American College of Rheumatology for the Classification of Takayasu Arteritis Criteria Definition Age at disease onset in year  Development of symptoms or findings related to Takayasu arteritis at age <40 years.  Claudication of extremities  Development and worsening of fatigue and discomfort in muscles of one or more extremity while in use, especially the upper extremities.  Decreased brachial artery pulse Decreased pulsation of one or both the brachial arteries BP difference >10mmHg Difference of >10mmHg in systolic blood pressure between arms  Bruit over subclavian arteries or aorta Bruit audible on auscultation over one or both subclavian arteries or abdominal aorta Arteriogram abnormality  Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal uppper or lower extremities, not due arteriosclerosis, fibro-muscular dysplasia, or similar causes: changes usually focal or segmental  For purposes of classification, a patient shall be said to have Takayasu's arteritis if at least three of these six criteria are present. The presence of any three or more criteria yields a sensitivity of 90.5% and a specificity of 97.8%. BP = blood pressure (systolic) difference between arms
  • 42. TYPES TYPES 1 Aortic arch and branches 2 Abdominal aorta 3 Both arch and abdominal aorta 4 Pulmonary artery
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