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GRUPO Nº 10
1.- SIGNS AND SYMPTOMS OF ACUTE BATONELOSIS

       Pallor               Jaundice




    Fever and malaise
Lymphadenopathy   Splenomegaly




                   Hepatomegaly
CHRONIC PHASE

DEFINITION
• It is characterized by an eruptive phase in
  which patients develop a skin reaction .

TYPES
• Miliary (1-4 mm).
• Nodular or sub dermal.
• Bottlenose (> 5 mm).
discomfort


    fever                                 arthralgia




bleeding
                 SYMPTOMS
                                               hepato-
 of the                                       splenome
  wart                                           galy




            myalgia                lymphade
                                    nopathy
EPIDEMIOLOGY

• Is found only in Peru,
 Ecuador, and Colombia.
• Existence of the
disease in new altitudes
(> 3,000 m).
DIAGNOSTIC


                      A suspected case of bartonellosis
                      everything you take a blood sample to
                      smear and thick at the first visit and
                      second and third sample at 12 and 24
                      hours respectively, if necessary.




Endothelial cell proliferation and new        The routine diagnostic procedure
formation of blood vessels at the level       it is the examination of blood
of papillary dermis (a whitehead)             smears and thick and can be
lattice (a papule) and even the               complemented by serology, blood
subcutaneous (nodular).                               and/or mielocultivo|
Male 26 years old, a native
of Lima Carhuaz from where you live 5 years
ago, the carrier.



30 days ago refers musculoskeletal paining lower
back and thighs, progressive pallor,
dyspnea, abdominal pain, headache, prostration,
etc.



He noted drowsy, pale, febrile, jaundiced skin and
mucous membranes, petechiae on arms.
The evolution makes severe epistaxis, edema of lower limbs
and sacrum, syndrome, and abscises(ultrasound).




The study was conducted 3/14/98 hematology in peripheral
blood shows mild
anemia, bartonellosis coccobacillary 28% myeloblastic reacti
on.




This case was diagnosed
asacute bartonellosis complicated with severe
thrombocytopenia.
TREATMENT
• In general it is recommended to use:
                   • Plus a second antimicrobial
                     agent (a lactam beta)
                   • For the effective treatment of
 CHLORAMPHENICOL     B. bacilliformis and protect
                     against any secondary
                     bacterial infection




  CIPROFLOXACIN,   • The rifampin or streptomycin
  STREPTOMYCIN,      is used to treat chronic
 TETRACYCLINE OR     bartonellosis.
  ERYTHROMYCIN
TREATMENT
                             Every third day for 14 days plus a
CHLORAMPHENICOL (500 mg      beta lactam



CIPROFLOXACIN (500 mg)       Every 12 h /during 10 days



RIFAMPIN (10 mg/kg)          Every day/during 14 days



STREPTOMICYNA(15-20 mg/kg)   Every day/during 10 days

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Bartonelosis

  • 2. 1.- SIGNS AND SYMPTOMS OF ACUTE BATONELOSIS Pallor Jaundice Fever and malaise
  • 3. Lymphadenopathy Splenomegaly Hepatomegaly
  • 4. CHRONIC PHASE DEFINITION • It is characterized by an eruptive phase in which patients develop a skin reaction . TYPES • Miliary (1-4 mm). • Nodular or sub dermal. • Bottlenose (> 5 mm).
  • 5. discomfort fever arthralgia bleeding SYMPTOMS hepato- of the splenome wart galy myalgia lymphade nopathy
  • 6. EPIDEMIOLOGY • Is found only in Peru, Ecuador, and Colombia. • Existence of the disease in new altitudes (> 3,000 m).
  • 7. DIAGNOSTIC A suspected case of bartonellosis everything you take a blood sample to smear and thick at the first visit and second and third sample at 12 and 24 hours respectively, if necessary. Endothelial cell proliferation and new The routine diagnostic procedure formation of blood vessels at the level it is the examination of blood of papillary dermis (a whitehead) smears and thick and can be lattice (a papule) and even the complemented by serology, blood subcutaneous (nodular). and/or mielocultivo|
  • 8.
  • 9. Male 26 years old, a native of Lima Carhuaz from where you live 5 years ago, the carrier. 30 days ago refers musculoskeletal paining lower back and thighs, progressive pallor, dyspnea, abdominal pain, headache, prostration, etc. He noted drowsy, pale, febrile, jaundiced skin and mucous membranes, petechiae on arms.
  • 10. The evolution makes severe epistaxis, edema of lower limbs and sacrum, syndrome, and abscises(ultrasound). The study was conducted 3/14/98 hematology in peripheral blood shows mild anemia, bartonellosis coccobacillary 28% myeloblastic reacti on. This case was diagnosed asacute bartonellosis complicated with severe thrombocytopenia.
  • 11. TREATMENT • In general it is recommended to use: • Plus a second antimicrobial agent (a lactam beta) • For the effective treatment of CHLORAMPHENICOL B. bacilliformis and protect against any secondary bacterial infection CIPROFLOXACIN, • The rifampin or streptomycin STREPTOMYCIN, is used to treat chronic TETRACYCLINE OR bartonellosis. ERYTHROMYCIN
  • 12. TREATMENT Every third day for 14 days plus a CHLORAMPHENICOL (500 mg beta lactam CIPROFLOXACIN (500 mg) Every 12 h /during 10 days RIFAMPIN (10 mg/kg) Every day/during 14 days STREPTOMICYNA(15-20 mg/kg) Every day/during 10 days