4. CHRONIC PHASE
DEFINITION
• It is characterized by an eruptive phase in
which patients develop a skin reaction .
TYPES
• Miliary (1-4 mm).
• Nodular or sub dermal.
• Bottlenose (> 5 mm).
5. discomfort
fever arthralgia
bleeding
SYMPTOMS
hepato-
of the splenome
wart galy
myalgia lymphade
nopathy
6. EPIDEMIOLOGY
• Is found only in Peru,
Ecuador, and Colombia.
• Existence of the
disease in new altitudes
(> 3,000 m).
7. DIAGNOSTIC
A suspected case of bartonellosis
everything you take a blood sample to
smear and thick at the first visit and
second and third sample at 12 and 24
hours respectively, if necessary.
Endothelial cell proliferation and new The routine diagnostic procedure
formation of blood vessels at the level it is the examination of blood
of papillary dermis (a whitehead) smears and thick and can be
lattice (a papule) and even the complemented by serology, blood
subcutaneous (nodular). and/or mielocultivo|
8.
9. Male 26 years old, a native
of Lima Carhuaz from where you live 5 years
ago, the carrier.
30 days ago refers musculoskeletal paining lower
back and thighs, progressive pallor,
dyspnea, abdominal pain, headache, prostration,
etc.
He noted drowsy, pale, febrile, jaundiced skin and
mucous membranes, petechiae on arms.
10. The evolution makes severe epistaxis, edema of lower limbs
and sacrum, syndrome, and abscises(ultrasound).
The study was conducted 3/14/98 hematology in peripheral
blood shows mild
anemia, bartonellosis coccobacillary 28% myeloblastic reacti
on.
This case was diagnosed
asacute bartonellosis complicated with severe
thrombocytopenia.
11. TREATMENT
• In general it is recommended to use:
• Plus a second antimicrobial
agent (a lactam beta)
• For the effective treatment of
CHLORAMPHENICOL B. bacilliformis and protect
against any secondary
bacterial infection
CIPROFLOXACIN, • The rifampin or streptomycin
STREPTOMYCIN, is used to treat chronic
TETRACYCLINE OR bartonellosis.
ERYTHROMYCIN
12. TREATMENT
Every third day for 14 days plus a
CHLORAMPHENICOL (500 mg beta lactam
CIPROFLOXACIN (500 mg) Every 12 h /during 10 days
RIFAMPIN (10 mg/kg) Every day/during 14 days
STREPTOMICYNA(15-20 mg/kg) Every day/during 10 days