1. NAME – ABHINAB DAS
REGD NO – 11MSM0052
GUIDE- DR. K.SUTHINDHIRAN
ASSISTANT PROFESSOR
SBST, VIT UNIVERSITY
2. Marine Algae are a very large and diverse group of simple, typically autotrophic organism ranging from
unicellular to multicellular.
USES
Agar
Fertilizer
Nutrition
MEDICINAL IMPORTANCE OF ALGAE
Antioxidant properties
Anticancer activities
Antibacterial activities.
Anti-diabetic property
ALGAE
MICROALGAE MACROALGAE
RED ALGAE GREEN ALGAE BROWN
ALGAE
3. AIM
The aim of our study is to investigate the antioxidant, antidiabetic and anticancer activity of
marine algae.
OBJECTIVE
The main objective of this dissertation: Sample collection, Extraction, Phytochemical analysis,
Antioxidant activity, Antibacterial activity, MIC, Recovery, α- amylase activity, α-
glucosidase activity, HDAC activity & GC-MS analysis.
4. Sample collection
Extraction
Phytochemical analysis (Hanaa et al., 2009)
Antioxidant activity (DPPH method) (M.A Jayasri et al., 2009)
Antibacterial by well diffusion method
MIC test
Recovery
α- amylase activity (M.A Jayasri et al., 2009)
α- glucosidase activity (M.A Jayasri et al., 2009)
HDAC inhibitory activity (By KIT method)
GC-MS analysis
22. Cladophora rupestris, Chaetomorpha antennina & Ulva linza had showed
good inhibitory results in antioxidant and antidiabetic inhibition assays.
Therefore it can be used in dietry supplements and in therapeutic use for
the treatment of diabetes. Though Butyric acid has good antioxidant
property, It also inhibits colonic tumor cells. The most important property
of Butyric acid is that, it can act as a HDAC inhibitor, inhibiting the
function of Histone Deacetylase enzymes. Due to present of Butyric acid in
these three marine seaweeds we can say that marine seaweeds have anti-
cancer properties. Therefore it can be used as antidiabetic properties and in
therapeautic use for the treatment of cancer.
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