Brief Introduction to the HTA Core Model (r), Anna Nachtnebel, LBI-HTA Presentation from the 3rd face to face training course for EUnetHTA Stakeholders organised by EUnetHTA JA2 WP2; April 23rd, 2015, Brussels.

1. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
The HTA Core Model ®
A brief introduction
Anna Nachtnebel, Ludwig Boltzmann Institute for HTA, Vienna, Austria
Third WP2 Face to Face Training Course for EUnetHTA stakeholders,
Brussels, 23rd of April 2015

2. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Key Aims of the HTA Core Model
 To capture the shareable „core“ of HTA
 To enable production of structured HTA information
and sharing of acquired knowledge
 To support joint HTA production
 To support local HTA production
April 25, 2013 2

3. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Starting points
Two problems:
HTA implemented differently across Europe –
reduced applicability of foreign reports
Varying structure of reports – extraction of data from
reports is often difficult
Aim: attempt to defined and standardise elements of an
HTA to facilitate shared understanding of HTA and
promote international use of HTA results
May 8, 2015 3

4. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
The Domains of the HTA Core Model®
HTA Core Model DOMAINS
1. Health problem and current use of technology
2. Description and technical characteristics
3. Safety
4. Clinical effectiveness
5. Costs and economic evaluation
6. Ethical analysis
7. Organisational aspects
8. Social aspects
9. Legal aspects
SCOPE
Rapid
Full
Reliable,timely,transparent,
transferableHTAinformation
Value???

5. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Rapid HTA Core Model
55
= checklist for ethical,
organizational, social
and legal issues

6. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Within each domains – several issues
HTA Core Model DOMAINS
1. Health problem and current use of technology
A0001: For which health conditions, and for what purposes is the
technology used?
A0002: What is the disease or health condition in the scope of this
assessment?
A0003: What are the known risk factors for the disease or health
condition?
4. Clinical effectiveness
D0001:What is the expected beneficial effect of the intervention on mortality?
D0020: Does use of the test lead to improved detection of the condition?

7. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Core HTAs contain an extensive assessment of health technology through
utilizing all nine domains of HTA included in the HTA Core Model.
Rapid HTAs contain a narrower analysis of health technology, limited to a
subset of domains and performed typically in a faster pace
5 applications:
• Diagnostic technologies
• Medical and surgical interventions
• Pharmaceuticals
• Screening technologies
• Rapid REA (for pharmaceuticals) only first 4 domains are assessed
HTA Core Model
7
Core HTA

8. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
The Domains of the
HTA Core Model®
HTA Core Model DOMAINS Med Tec Pharma
Diagnosti
cs
Screening
Rapid
REA
1. Health problem and current use of technology
A0001: For which health
conditions, and for what purposes is
the technology used?
critical critical critical critical critical
A0002: What is the disease or
health condition in the scope of this
assessment?
critical critical critical critical critical
A0003: What are the known risk
factors for the disease or health
condition?
important Important important critical
import
ant
4. Clinical effectiveness
D0001:What is the expected
beneficial effect of the intervention on
mortality?
critical Critical critical critical critical
D0020: Does use of the test lead to
improved detection of the condition?
- - important important -

9. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
 Longer timeframe as a full HTA Core assessment is
conducted - detailed information
 Relevant sets of information for producing a HTA report
– shareable/ transferable information
 HTA core information structured through nine relevant
domains – comprehensive information
 Cross-border collaboration, quality assurance –
reliable and transparent information
Full HTA Core Model

10. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Rapid HTA Core Model
 Rapid timeframe as assessment characteristics are adapted to national
reimbursement context – timely information
 Similar set of information within the four domains and European
countries – shareable/ transferable information
 A compact and easy-to-read format – useful information
 Cross-border collaboration, quality assurance – reliable and
transparent information
10

11. European network for Health Technology Assessment | JA2 2012-2015 | www.eunethta.eu
Thank you!
This presentation arises from the EUnetHTA
Joint Action 2 which has received funding
from the European Union, in the framework of
the Health Programme