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IVC-Guided Fluid
Management in the
ICU
DR. HATEM A. SOLIMAN, MSC, MRCP
MAFRAQ HOSPITAL
CRITICAL CARE CME PROGRAM
Outline
• Anatomy
• Physiology
• Main Idea
• Procedure
• Pearls & Pitfalls
• Take home message
• References
• Useful Resources
Anatomy
Anatomy
• The IVC returns blood from the
body to the right atrium
• Formed by the convergence
of the illiac
veins
• Retroperitoneal
• Right of the aorta
• Normal size 1.5-2.5 cm
• During expiration,
• In a spontaneously breathing
patient,
• Just distal the hepatic vein
• Varies with respiration
Physiology
Respiratory Variation
“Due to changing intra-thoracic pressures”
• Expands with expiration
• Narrows with inspiration
“The opposite in MV patients”
Respiratory Variation
Respiratory Variation
CAVAL INDEX (CI)
CI =
Minimal diameter
Maximal diameter
Maximum diameter
X 100 (%)
CAVAL INDEX (IVCI)
Volume
Depletion
Volume
Overload
0% 100%
IVCI >18% (ventilated)IVCI <10% (ventilated)
Main Idea
Main Idea
• Change of IVC diameter > 50% = possible hypovolemia.
• Change of < 20% indicates = will probably not respond
to fluid challenge.
• IVCD < 0.9 cm (spont. breathing), < 1.2 (ventilated) =
Hypovolemia (COP likely to increase after Fluid Challenge).
• IVCD > 2 cm = Euvol./Hypervolemia
(No response to Fluid Challenge).
IVC vs. CVP Guidelines
IVC vs. CVP Guidelines
PROCEDURE
Positioning
• Supine
• Degree of head elevation has not
been shown to make a significant
difference in measurements
Probe Selection
• Low frequency (2-5 MHz)
• Curvi-linear (Abdominal), or
Phased array (Cardiac)
Curvi-linear Probe
Phased-array Probe
• Most common approach
• Place probe longitudinally just below the xiphoid
process with the probe marker to the patient’s
head (Curvi-linear Probe)
• Look for IVC going into right atrium – may need to
move probe 1-2cm to patient’s right and then tilt it
slightly towards the heart
Xiphoid View
Xiphoid View
Xiphoid View
Xiphoid View
IVC Longitudinal
IVC Longitudinal
Anterior Mid-Axillary View
Anterior Mid-Axillary View
• Place probe longitudinally in right anterior mid-
axillary line with marker towards the head
• Look for IVC running longitudinally adjacent to liver
crossing the diaphragm.
• Track superiorly until it enters right atrium
confirming that it is the IVC and not the aorta.
• Similar to Morrison’s pouch view in FAST exam?!
Anterior Mid-Axillary View
Measuring the IVC Diameter
2 cm distal to right atrium or just distal to the hepatic vein
Minimal IVC Diameter
Maximal IVC Diameter
M-Mode IVC Diameters
M-Mode Volume Depletion
M-Mode Volume Overload
Pearls & Pitfalls
Pearls & Pitfalls
Bowel Gas
1 May impede visualization in the
xiphoid view
2 Gentle graded pressure may help
move bowel out of way
3 Don’t press too hard or will collapse
IVC causing false measurements
4 Consider anterior mid-axillary view
Plethoric (dilated) IVC
• Volume overload.
• Obstructive Shock:
• Cardiac tamponade
• Tension Pneumothorax.
• Massive PE.
Pearls & Pitfalls
Plethoric (dilated) IVC
• Mitral regurgitation
• Aortic stenosis
• Status Asthmaticus
• Right Heart Failure.
Pearls & Pitfalls
Mechanical Ventilation
Causes reversal of IVC changes with
respiration
“Maximum diameter with inspiration, minimum
diameter with expiration”
Pearls & Pitfalls
(False) Collapse of IVC
• Diaphragmatic breathing (Kimura 2011)
“Important in the ICU”
• Raised intra-abdominal pressure
(in animal studies: Takata 1990)
• Even pressure from the probe! (anecdotally)
Pearls & Pitfalls
Aorta
Thick, echogenic walls
Pulsatile
High flow velocity
Non-compressible
No respiratory variation
Above vertebral bodies
IVC
Thin walled
Usually not pulsatile
Low flow velocity
Compressible
Respiratory variation
To the right of vertebral
bodies
IVC vs. Aorta
Pearls & Pitfalls
Aorta (Longitudinal View)
IVC vs. Aorta
Take Home
Message
Take Home Message
Shock + flat collapsing IVC = give
fluid.
<0.9cm (spontaneous breathing)
<1.2cm IVCD, CI >18% (ventilated)
Shock + distended IVC = don’t give
fluid.
>2.5cm, IVCCI <10% (ventilated)
Take Home Message
Serial IVC measurements seem useful!
Take Home Message
IVC probably does help at extremes
(Fat & Full Vs. Flat & Collapsing).
Take Home Message
Mobile Apps
EGLS
SonoAccess
PHILIPS US Education App
Not the US result!
Remember
Treat the Patient
“The value of experience is not in
seeing much, but in seeing wisely”
William Osler
References
• ACEP Policy Statement on Emergency Ultrasound Guidelines. Ann. Emerg. Med. 2009;53:550-70
• De Lorenzo RA, Morris MJ, William JB, et al. Does a simple bedside sonographic measurement
of the inferior vena cava correlate to central venous pressure? J. Emer. Med. 2011; 42(4);
429-436.
• Kosiak W, Swieton D, Piskunowicz M. Sonographic inferior vena cava/aorta diameter index, a new
approach to the body fluid status assessment in children and young adults in emergency
ultrasound preliminary study. Acad. J. Emerg. Med. 2008;26:320-5
• Nagdev AD, Merchant RC, Tirado-Gonzalez A, et al. Emergency department bedside
ultrasonographic measurement of the caval index for noninvasive determination of low central
venouspressure. Ann.Emerg.Med. 2010;55:290-5.
• Feissel M, Michard F, Faller JP, et al. The respiratory variation in inferior vena cava diameter
as a guide to fluid therapy. Intensive Care Med. 2004;30:1834-7.
• Fields JM, Lee PA, Jenq KY, et al. The interrater reliability of inferior vena cava ultrasound by
bedside clinician sonographers in emergency department patients. Acad. Emerg. Med. 2011;18:98-
101.
• Kircher BJ, Himelman RB, Schiller NB. Noninvasive estimation of right atrial pressure from the
inspiratory collapse of the inferior vena cava. Am J. Cardiol. 1990;66:493-6.
• Emcrit.org.
Useful Links
www.Lifeinthefastlane.com
www.sonosite.com
www.criticalecho.com
www.intensivecarenetwork.com/icusonogra
phy
www.emcrit.org
www.sinaiem.us
www.sonospot.com
www.emergencyultrasoundteaching.com
www.thesonocave.com
“Patch
Adams”
Thank You

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