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Antimicrobial
Resistance
Hub
Barbara Wieland, ILRI
CGIAR Antimicrobial Resistance Hub Launching, ILRI
Nairobi, 21-22 February 2019
Managing partners
Supported by
Overview
• Photos of all involved in making this happen
AMR is a big mountain to climb
AMR is a big mountain to climb
AMR in the CGIAR: Activity focus
Partnerships
AM use and
value chains
Transmission
dynamics
Interventions
Enabling
policy
Capacity
Research & Development
• Context-driven and systems-oriented research that
combines social and biological sciences
• Understanding linkages of agriculture and aquaculture with
public health outcomes
• Generate solutions that work and can be scaled
• Focus on enabling environment with evidence-policy
support and various capacity development activities to
achieve impact
Antimicrobial use, behaviour and value chains
We research behaviour around antimicrobials used, the distribution networks of
veterinary drugs, and the role of formal and informal markets in perpetuating
cycles of inequity.
Outputs:
• Metrics for AM use in different systems
• Better understanding of systems
influencing AM use behaviour
Transmission dynamics, AMR residues
To better understand AMR risks for people, we study the biology,
ecology, and epidemiology of resistant microbes at the animal,
human and environment interface.
Outputs
• adequate study designs for genotyping research
• evidence on the extent of antimicrobial-resistant bacteria and
antimicrobial residues found in livestock, fish, humans, the
environment, water and food
• transmission and genetic mechanisms of resistance in
agriculture and health implications
Interventions and incentives
Based on One Health approaches, we design, test and evaluate
interventions and incentives that lead to behavioural change and
reduce agriculture-associated AMR.
Outputs
• Typologies of interventions
• Decision support tools to
identify best-bet interventions
• Gender sensitive interventions
to mange drivers of AM use
• Cost and benefits of
interventions from a One
Health perspective
Enabling policy environment
We translate evidence into convincing
arguments to engage policymakers and
other stakeholders in the AMR
discussion. Accepted and feasible
policies are key for sustainable solutions
that achieve impact.
Outputs
• Synthesized evidence for policy
makers
• Advocacy materials
• Integrated policy approaches
towards One Health solutions
Capacity development
Capacity development is a key enabler on the pathway to impact.
An important area of research is how solutions can be brought to
scale. We capitalize on a network of AMR experts to support
capacity building on researching AMR issues and to facilitate access
to international AMR research for professionals and institutions in
LMICs.
Outputs
• Guidance for scaling of
interventions
• Training, mentorship and
exchange programs
• Training materials
Role of the hub
• Convene stakeholders of different disciplines with interest
in antimicrobial resistance research and development
• Provide an enabling environment for research partnerships
• Better communication around agriculture-associated
antimicrobial resistance, esp. across CGIAR
• Target different stakeholder groups
Partnerships as critical
factor for success
Ability to excite and convene national
partners in technical, institutional and
policy innovations
Ability to facilitate true One Health
partnerships
-Ability to engage with international
organization for effective linkages
- Adequate human and financial
resources to establish a critical mass of
researchers and partners
AM use and
value chains
Transmission
dynamics
InterventionsEnabling
policy
Capacity
What the AMR hub can offer
• Convene stakeholders on AMR to discuss solutions
• Host and maintain an online agri-food system AMR
information platform: www.amr.cgiar.org
• Host a longterm biobank
• Run a data storage platform for AMR related CGIAR projects
• Organise regular trainings on different aspects of AMR for
CGIAR and national partner institutions involved in AMR
work
• Discuss CGIAR positioning on AMR research
Partner event- goals
• Clarify how the hub can be at the service of our partners
• Case studies
• Discussions on challenges in the implementation of AMR
control strategies
• Possible research gaps and capacity building needs
emerging from those
• Build new partnerships
• Discuss ideas and approaches
For more information:
www.amr.cgiar.org
Antimicrobial
Resistance
Hub
www.amr.cgiar.org

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Antimicrobial Resistance Hub

  • 1. Antimicrobial Resistance Hub Barbara Wieland, ILRI CGIAR Antimicrobial Resistance Hub Launching, ILRI Nairobi, 21-22 February 2019 Managing partners Supported by
  • 2. Overview • Photos of all involved in making this happen AMR is a big mountain to climb
  • 3.
  • 4. AMR is a big mountain to climb
  • 5. AMR in the CGIAR: Activity focus Partnerships AM use and value chains Transmission dynamics Interventions Enabling policy Capacity
  • 6. Research & Development • Context-driven and systems-oriented research that combines social and biological sciences • Understanding linkages of agriculture and aquaculture with public health outcomes • Generate solutions that work and can be scaled • Focus on enabling environment with evidence-policy support and various capacity development activities to achieve impact
  • 7. Antimicrobial use, behaviour and value chains We research behaviour around antimicrobials used, the distribution networks of veterinary drugs, and the role of formal and informal markets in perpetuating cycles of inequity. Outputs: • Metrics for AM use in different systems • Better understanding of systems influencing AM use behaviour
  • 8. Transmission dynamics, AMR residues To better understand AMR risks for people, we study the biology, ecology, and epidemiology of resistant microbes at the animal, human and environment interface. Outputs • adequate study designs for genotyping research • evidence on the extent of antimicrobial-resistant bacteria and antimicrobial residues found in livestock, fish, humans, the environment, water and food • transmission and genetic mechanisms of resistance in agriculture and health implications
  • 9. Interventions and incentives Based on One Health approaches, we design, test and evaluate interventions and incentives that lead to behavioural change and reduce agriculture-associated AMR. Outputs • Typologies of interventions • Decision support tools to identify best-bet interventions • Gender sensitive interventions to mange drivers of AM use • Cost and benefits of interventions from a One Health perspective
  • 10. Enabling policy environment We translate evidence into convincing arguments to engage policymakers and other stakeholders in the AMR discussion. Accepted and feasible policies are key for sustainable solutions that achieve impact. Outputs • Synthesized evidence for policy makers • Advocacy materials • Integrated policy approaches towards One Health solutions
  • 11. Capacity development Capacity development is a key enabler on the pathway to impact. An important area of research is how solutions can be brought to scale. We capitalize on a network of AMR experts to support capacity building on researching AMR issues and to facilitate access to international AMR research for professionals and institutions in LMICs. Outputs • Guidance for scaling of interventions • Training, mentorship and exchange programs • Training materials
  • 12. Role of the hub • Convene stakeholders of different disciplines with interest in antimicrobial resistance research and development • Provide an enabling environment for research partnerships • Better communication around agriculture-associated antimicrobial resistance, esp. across CGIAR • Target different stakeholder groups
  • 13. Partnerships as critical factor for success Ability to excite and convene national partners in technical, institutional and policy innovations Ability to facilitate true One Health partnerships -Ability to engage with international organization for effective linkages - Adequate human and financial resources to establish a critical mass of researchers and partners AM use and value chains Transmission dynamics InterventionsEnabling policy Capacity
  • 14.
  • 15. What the AMR hub can offer • Convene stakeholders on AMR to discuss solutions • Host and maintain an online agri-food system AMR information platform: www.amr.cgiar.org • Host a longterm biobank • Run a data storage platform for AMR related CGIAR projects • Organise regular trainings on different aspects of AMR for CGIAR and national partner institutions involved in AMR work • Discuss CGIAR positioning on AMR research
  • 16. Partner event- goals • Clarify how the hub can be at the service of our partners • Case studies • Discussions on challenges in the implementation of AMR control strategies • Possible research gaps and capacity building needs emerging from those • Build new partnerships • Discuss ideas and approaches