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CT Brain Perfusion
Toshiba Aquilion 64
Department Workflow
1.

2.

3.

EMS alerts facility to prepare for arrival of potential stroke victim.
1.1. Is patient inside the time window for t-PA? (3 hours from onset of
symptoms).
Facility alerts necessary personnel (We utilized pagers)
2.1. CT Department
2.2. Emergency Department personnel
2.3. Respiratory Therapy (if needed)
EMS transports patient directly to CT department
3.1. Emergency department personnel are waiting in CT with appropriate
life sustaining equipment, monitor, and stretcher.
3.2. If respiratory therapy is needed, they would be waiting in CT with a
ventilator.
Department Workflow
4.

5.

Patient is put on monitor and transferred to CT table.
4.1. Observations are made by the CT Technologist of patient
regarding facial droop, fixed gaze, slurred speech, numbness
etc…
4.2. Vital signs are documented by attending nurse.
Head w/o contrast is performed and evaluated by CT personnel for
hemorrhage.
5.1. If there is no hemorrhage CT perfusion can be performed.
(Technologists need to be trained to identify brain bleed)
5.2. Head w/o contrast is sent to radiologist or off site reading
service for immediate interpretation.
5.3. 25 minute result time is required
Department Workflow
6.
7.

8.
9.
10.
11.

CT brain perfusion is performed according to department protocol
6.1. CT brain perfusion series sets are sent to VITREA for mapping.
CT Head and Neck is performed.
7.1. Post processing including coronal, sagittal, and 360 degree rotational
MIPS are performed (of each internal carotid artery).
7.2. Post Processing of Brain (Coronal, Sagittal, and Axial MIP’s)
Patient is transported back to Emergency Department.
CT Perfusion mapping results and CTA head and neck are sent to radiologist or
off site reading service for interpretation.
If stroke is identified in Head w/o contrast, either t-PA is administered or
MERCI procedure is performed in Special Procedures. (as per facility
policy)
Standard for resulting of all studies was 45 minutes from door time to final
resulting.
Scan Parameters
Scan mode

DualScano ( 0 and 90 degrees)

kV

120

mA

50

Range

240.0

Scan Angle

0

CE

Off

Direction

OUT

Scan Mode

Dynamic

Thickness

4 Rows (8.0x 4)

kV

80

mA

150 – 200

Rotation Time

1.0 sec

Scan Time

50 sec

SureExp

Off

CE

On

SureIQ

CBP

Image Thickness

8.0

Recon Interval

1.0
Protocol Screenshots

80
Protocol Screenshots
Positioning
• Position as you would for a normal

Head CT.
• Immobilize as necessary
• Once you have obtained a SCANO
image position your DYNAMIC slice
marker as image demonstrates
• Stay in line with the base of skull
and approximately 1cm Superior to
the Sella Turcica. (This will image
the necessary vascular structures
(see Picture next slide).
Positioning
Positioning / Scanning Notes
• Notice that the area imaged includes from the Supra Sellar region through
the superior portion of the Circle of Willis. This includes all the necessary
vascular structures pertinent to the diagnosis of stroke and the ability for
mapping to occur with success.
• We have used 80 kV as low contrast resolution isn’t as important due to
the fact that we are only interested in contrasted areas of the vascular
structures. It also serves to reduce patient dose. Reduced mA also serves
this same purpose and anywhere between 100-200 mA has been proven to
be sufficient.
Positioning / Scanning Notes
• Inject 50ml of 370 Contrast at a rate of 4-6ml/sec. followed by 50 ml Saline Flush
• 18g or 20g IV (Right Arm Preferred)

• Since it takes approximately 15-22 secs for contrast to reach the basilar artery,
you can do one of two things, you can build a delay into the protocol itself and
start your time at the same time you start contrast, or you can start the contrast
injection and wait to start your scan manually without any delay built in. This
helps to reduce dose to the patient where no useful imaging is being performed.
While non-contrasted images are important for the mapping, it is unnecessary to
radiate a patient for 10-15 secs without need. Venous flow begins to drop off at
approximately 35-45 secs.
Positioning / Scanning Notes
While actively scanning you will see contrast begin to perfuse the brain, there will be 2 distinct
phases, Arterial and Venous. These phases are important for mapping in terms of CBF, CBV, MTT, and
TTP.
CBF – Cerebral Blood Flow
Flow rate of volume of blood through cerebral vasculature.
(ml/100gm/min)
CBV – Cerebral Blood Volume
Volume of flowing blood. (ml/100gm)
MTT – Mean Transit Time
Time required for blood to pass through tissue. (sec)
TTP – Time to Peak
Sensitive measure of decrease in flow
These maps will be used to demonstrate the vascular flow pattern to further identify a stroke and the
level of severity, including penumbra. (Refer to the VITREA Brain Perfusion manual I have included for
additional information and instructions on mapping.)

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Ct Brain Perfusion - Toshiba Aquilion 64

  • 2. Department Workflow 1. 2. 3. EMS alerts facility to prepare for arrival of potential stroke victim. 1.1. Is patient inside the time window for t-PA? (3 hours from onset of symptoms). Facility alerts necessary personnel (We utilized pagers) 2.1. CT Department 2.2. Emergency Department personnel 2.3. Respiratory Therapy (if needed) EMS transports patient directly to CT department 3.1. Emergency department personnel are waiting in CT with appropriate life sustaining equipment, monitor, and stretcher. 3.2. If respiratory therapy is needed, they would be waiting in CT with a ventilator.
  • 3. Department Workflow 4. 5. Patient is put on monitor and transferred to CT table. 4.1. Observations are made by the CT Technologist of patient regarding facial droop, fixed gaze, slurred speech, numbness etc… 4.2. Vital signs are documented by attending nurse. Head w/o contrast is performed and evaluated by CT personnel for hemorrhage. 5.1. If there is no hemorrhage CT perfusion can be performed. (Technologists need to be trained to identify brain bleed) 5.2. Head w/o contrast is sent to radiologist or off site reading service for immediate interpretation. 5.3. 25 minute result time is required
  • 4. Department Workflow 6. 7. 8. 9. 10. 11. CT brain perfusion is performed according to department protocol 6.1. CT brain perfusion series sets are sent to VITREA for mapping. CT Head and Neck is performed. 7.1. Post processing including coronal, sagittal, and 360 degree rotational MIPS are performed (of each internal carotid artery). 7.2. Post Processing of Brain (Coronal, Sagittal, and Axial MIP’s) Patient is transported back to Emergency Department. CT Perfusion mapping results and CTA head and neck are sent to radiologist or off site reading service for interpretation. If stroke is identified in Head w/o contrast, either t-PA is administered or MERCI procedure is performed in Special Procedures. (as per facility policy) Standard for resulting of all studies was 45 minutes from door time to final resulting.
  • 5. Scan Parameters Scan mode DualScano ( 0 and 90 degrees) kV 120 mA 50 Range 240.0 Scan Angle 0 CE Off Direction OUT Scan Mode Dynamic Thickness 4 Rows (8.0x 4) kV 80 mA 150 – 200 Rotation Time 1.0 sec Scan Time 50 sec SureExp Off CE On SureIQ CBP Image Thickness 8.0 Recon Interval 1.0
  • 8. Positioning • Position as you would for a normal Head CT. • Immobilize as necessary • Once you have obtained a SCANO image position your DYNAMIC slice marker as image demonstrates • Stay in line with the base of skull and approximately 1cm Superior to the Sella Turcica. (This will image the necessary vascular structures (see Picture next slide).
  • 10. Positioning / Scanning Notes • Notice that the area imaged includes from the Supra Sellar region through the superior portion of the Circle of Willis. This includes all the necessary vascular structures pertinent to the diagnosis of stroke and the ability for mapping to occur with success. • We have used 80 kV as low contrast resolution isn’t as important due to the fact that we are only interested in contrasted areas of the vascular structures. It also serves to reduce patient dose. Reduced mA also serves this same purpose and anywhere between 100-200 mA has been proven to be sufficient.
  • 11. Positioning / Scanning Notes • Inject 50ml of 370 Contrast at a rate of 4-6ml/sec. followed by 50 ml Saline Flush • 18g or 20g IV (Right Arm Preferred) • Since it takes approximately 15-22 secs for contrast to reach the basilar artery, you can do one of two things, you can build a delay into the protocol itself and start your time at the same time you start contrast, or you can start the contrast injection and wait to start your scan manually without any delay built in. This helps to reduce dose to the patient where no useful imaging is being performed. While non-contrasted images are important for the mapping, it is unnecessary to radiate a patient for 10-15 secs without need. Venous flow begins to drop off at approximately 35-45 secs.
  • 12. Positioning / Scanning Notes While actively scanning you will see contrast begin to perfuse the brain, there will be 2 distinct phases, Arterial and Venous. These phases are important for mapping in terms of CBF, CBV, MTT, and TTP. CBF – Cerebral Blood Flow Flow rate of volume of blood through cerebral vasculature. (ml/100gm/min) CBV – Cerebral Blood Volume Volume of flowing blood. (ml/100gm) MTT – Mean Transit Time Time required for blood to pass through tissue. (sec) TTP – Time to Peak Sensitive measure of decrease in flow These maps will be used to demonstrate the vascular flow pattern to further identify a stroke and the level of severity, including penumbra. (Refer to the VITREA Brain Perfusion manual I have included for additional information and instructions on mapping.)