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Integrated
       Malaria
    Management
         (IMM)
 Integrating Mosquito and
 Malaria Control and Using
  Data to Drive Decisions


A health module of Community Analytics
                 (CA)
Integrated Malaria Management
Integrating Mosquito and Malaria Control
                       The aim of integrating mosquito and malaria
                       control is that very much more cost effective
                       results can be achieved in any community
                       through a multi-intervention approach than
                       any single intervention approach. With IMM
                       data are used to make plans and judge
                       results.
Modern science gives us the tools to have rapid and low cost
success ... but only if the program is driven by science and
facts about the situation, and the performance of program
interventions.
The goal is to reduce the negative impact of malaria in African
communities ... rapidly and at lowest possible cost.
Integrated Malaria Management

Disrupting the Continuing Cycle of Re-infection
                         A critical parameter of success is
                            reduction in the rate of re-
                            infection.
                         No matter how good the malaria
                           therapy, malaria will remain a
                           socio-economic problem of
                           major proportion as long as
                           there is a continuing cycle of re-
                           infection.
                         This is one of the reasons for the
                            build up of resistance to drugs,
                            and the reason that limited anti-
                            malarial programs do not
                            succeed.
Integrated Malaria Management

The IMMC Components

    Collect data (entomological data, environmental data, spatial
    data, medical data, cost data) and do thorough, rapid analysis
    to define and optimize interventions and program activities.

    Do environmental cleanup and get community involved.

    Use interior residual spraying (IRS) to control mosquitoes near
    human beings. Use best available insecticides, including DDT.

    Use larvicides to control (stop) the maturation of mosquitoes.

    Kill / control flying mosquito population using aerial and ground
    application of adulticides.

    Medical - malaria case management to improve health situation
    and reduce malaria parasite in the area.

    Use insecticide impregnated bednets to limit mosquito bites.
Integrated Malaria Management


       Management Process
                 Collect data
                 Do analysis
         Make operational decisions
              Collect more data
              Do more analysis
        Revise operational decisions
   Publish performance to all stakeholders
Integrated Malaria Management

Collect Data: Entomology




Collect data – get it from the habitat. Not comfortable, but very
important. Learn WHERE and what is going on with the
mosquito: larva ... mosquito population ... prevalence of
malaria in the mosquitoes ... etc.
Integrated Malaria Management

  Collect Data: Geographical




Left picture: A satellite image of Monrovia, Liberia, West Africa showing
15,000 acres of marsh within the main urban area (dark brown area)
Right picture: Aerial image of part of the urban area ... very congested
and difficult to access by vehicle.
Integrated Malaria Management

Collect Data – Malariology




Keep score ... the goal is to reduce the prevalence of malaria, and to do it
at least cost and in the most sustainable manner. Part of this requires
knowledge of issues like resistance and the cost and effectiveness of
various forms of therapy.
Integrated Malaria Management

  Collect Data – about malaria and treatment




Everyone needs to have access to treatment ... it is important for two
reasons: (1) the patients need treatment to get better and avoid getting
worse; and (2) good public health policy requires that there is a lowering of
malaria prevalence as fast as possible to give a sustainable outcome.
This child did not get adequate treatment ... this clinic did not have effective medications ... as reported in the
New York Times in June 2006
Integrated Malaria Management

Data analysis, cost and value optimization




Data is used to determine what interventions are most likely to give rapid
sustainable progress towards the ultimate goal of reducing malaria prevalence. A
cost and operations model suggests that best practice using multiple interventions
is several times more cost effective than any other approach.
Integrated Malaria Management


      Operational Components
              Environmental Cleanup
         Interior Residual Spraying (IRS)
                    Larviciding
  Exterior Spraying (Air ULV, Ground Fogging)
                Medical Treatment
                   Bednets (ITN)
Integrated Malaria Management

Environmental Cleanup




Stagnant water facilitates mosquito breeding. Cleanup is something
that people in all communities should undertake as a civic
responsibility. It takes education, leadership and motivation.
This can be organized through community groups like churches
and mosques, youth groups, soccer teams, etc.
This should be one of many IMMC interventions.
Integrated Malaria Management

Interior Residual Spraying (IRS)




Interior Residual Spraying (IRS) has been very effective in reducing the
incidence of malaria ... and especially when DDT is used as the primary
insecticide. IRS operates in three ways: (1) as a repellant that keep
mosquitoes outside the living space; (2) as an irritant that accelerates exit
of mosquitoes; and, (3) toxicity that kills mosquitoes.
Integrated Malaria Management
Larviciding




The best time to eliminate the mosquito vector is BEFORE the
mosquito can fly. This can be done with knowledge about the
environment and larviciding to kill larva before they become flying
mosquitoes.
Various approaches to larviciding are possible ... manual, with
mechanized support and, in some cases, using aerial application.
Integrated Malaria Management

Aerial Treatment – ULV, Adulticiding, Larviciding
                            
                                Aerial spraying makes
                                rapid treatment of large
                                and/or inaccessible areas
                                possible.
                            
                                Aerial operations are
                                expensive per hour, but
                                LOW COST in terms of
                                work done.
                            
                                Ultra Low Volume (ULV)
                                spraying does NO
                                environmental damage.
                            
                                Treatment strategy
                                determined by
                                entomological analysis.
Integrated Malaria Management

ULV Ground Fogging – mechanized and manual




Ultra Low Volume (ULV) and aerosol ground fogging is common
practice in places where malaria has been controlled. It serves to
reduce mosquito populations in areas reached by insecticide
sprays and limit malaria transmission.
A variety of chemicals are used that are highly toxic to mosquitoes
but safe for humans, animals and the environment. By varying the
chemicals used build up of resistance is minimized.
Integrated Malaria Management

Treatment
            The need for malaria treatment is
            enormous ... over 400 million cases a
            year in Africa. But most do not get
            effective treatment.
            Public funding for programs is small,
            and most individuals do not have their
            own resources. Untreated malaria can
            be fatal.
            Use effective drugs.
            Avoid building up drug resistance.
Integrated Malaria Management

  Insecticide Treated Bednets (ITN)
                                     Insecticide treated bednets
                                     (ITN) help reduce malaria
                                     transmission. They reduce
                                     contact with malaria infected
                                     mosquitoes and reduce malaria
                                     among people using bednets.
                                     But what about protection
                                     outside the house?

Widespread bednet use requires a lot of effort and bednets are
expensive relative to local incomes. ITN is a valuable part of a total
solution, but only a part. ITN cannot achieve full success on its own.
Integrated Malaria Management
Examples of success
Success in the early       The Panama Canal Zone around 1904.
part of the 20th Century   Most of temperate Europe ended malaria largely
                           by improved environment that reduced vector.

Immediate post WW2         USA eliminated endemic malaria
era to around 1960         Japan almost totally reduced malaria
(heavy use of DDT)         Italy and lastly Sardinia reduced malaria
                           India had major reduction in malaria prevalence
                           Considerable reduction in Caribbean locations
                           Considerable reduction in Latin America
                           Australia eliminated endemic malaria

Recent experience in       South Africa, Swaziland and Mozambique used
Africa                     regional control and IRS (including use of DDT) to
                           reduce malaria epidemic arising after about 10
                           years of no DDT use.
Integrated Malaria Management




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Imm presentation 002 091010

  • 1. Integrated Malaria Management (IMM) Integrating Mosquito and Malaria Control and Using Data to Drive Decisions A health module of Community Analytics (CA)
  • 2. Integrated Malaria Management Integrating Mosquito and Malaria Control The aim of integrating mosquito and malaria control is that very much more cost effective results can be achieved in any community through a multi-intervention approach than any single intervention approach. With IMM data are used to make plans and judge results. Modern science gives us the tools to have rapid and low cost success ... but only if the program is driven by science and facts about the situation, and the performance of program interventions. The goal is to reduce the negative impact of malaria in African communities ... rapidly and at lowest possible cost.
  • 3. Integrated Malaria Management Disrupting the Continuing Cycle of Re-infection A critical parameter of success is reduction in the rate of re- infection. No matter how good the malaria therapy, malaria will remain a socio-economic problem of major proportion as long as there is a continuing cycle of re- infection. This is one of the reasons for the build up of resistance to drugs, and the reason that limited anti- malarial programs do not succeed.
  • 4. Integrated Malaria Management The IMMC Components  Collect data (entomological data, environmental data, spatial data, medical data, cost data) and do thorough, rapid analysis to define and optimize interventions and program activities.  Do environmental cleanup and get community involved.  Use interior residual spraying (IRS) to control mosquitoes near human beings. Use best available insecticides, including DDT.  Use larvicides to control (stop) the maturation of mosquitoes.  Kill / control flying mosquito population using aerial and ground application of adulticides.  Medical - malaria case management to improve health situation and reduce malaria parasite in the area.  Use insecticide impregnated bednets to limit mosquito bites.
  • 5. Integrated Malaria Management Management Process Collect data Do analysis Make operational decisions Collect more data Do more analysis Revise operational decisions Publish performance to all stakeholders
  • 6. Integrated Malaria Management Collect Data: Entomology Collect data – get it from the habitat. Not comfortable, but very important. Learn WHERE and what is going on with the mosquito: larva ... mosquito population ... prevalence of malaria in the mosquitoes ... etc.
  • 7. Integrated Malaria Management Collect Data: Geographical Left picture: A satellite image of Monrovia, Liberia, West Africa showing 15,000 acres of marsh within the main urban area (dark brown area) Right picture: Aerial image of part of the urban area ... very congested and difficult to access by vehicle.
  • 8. Integrated Malaria Management Collect Data – Malariology Keep score ... the goal is to reduce the prevalence of malaria, and to do it at least cost and in the most sustainable manner. Part of this requires knowledge of issues like resistance and the cost and effectiveness of various forms of therapy.
  • 9. Integrated Malaria Management Collect Data – about malaria and treatment Everyone needs to have access to treatment ... it is important for two reasons: (1) the patients need treatment to get better and avoid getting worse; and (2) good public health policy requires that there is a lowering of malaria prevalence as fast as possible to give a sustainable outcome. This child did not get adequate treatment ... this clinic did not have effective medications ... as reported in the New York Times in June 2006
  • 10. Integrated Malaria Management Data analysis, cost and value optimization Data is used to determine what interventions are most likely to give rapid sustainable progress towards the ultimate goal of reducing malaria prevalence. A cost and operations model suggests that best practice using multiple interventions is several times more cost effective than any other approach.
  • 11. Integrated Malaria Management Operational Components Environmental Cleanup Interior Residual Spraying (IRS) Larviciding Exterior Spraying (Air ULV, Ground Fogging) Medical Treatment Bednets (ITN)
  • 12. Integrated Malaria Management Environmental Cleanup Stagnant water facilitates mosquito breeding. Cleanup is something that people in all communities should undertake as a civic responsibility. It takes education, leadership and motivation. This can be organized through community groups like churches and mosques, youth groups, soccer teams, etc. This should be one of many IMMC interventions.
  • 13. Integrated Malaria Management Interior Residual Spraying (IRS) Interior Residual Spraying (IRS) has been very effective in reducing the incidence of malaria ... and especially when DDT is used as the primary insecticide. IRS operates in three ways: (1) as a repellant that keep mosquitoes outside the living space; (2) as an irritant that accelerates exit of mosquitoes; and, (3) toxicity that kills mosquitoes.
  • 14. Integrated Malaria Management Larviciding The best time to eliminate the mosquito vector is BEFORE the mosquito can fly. This can be done with knowledge about the environment and larviciding to kill larva before they become flying mosquitoes. Various approaches to larviciding are possible ... manual, with mechanized support and, in some cases, using aerial application.
  • 15. Integrated Malaria Management Aerial Treatment – ULV, Adulticiding, Larviciding  Aerial spraying makes rapid treatment of large and/or inaccessible areas possible.  Aerial operations are expensive per hour, but LOW COST in terms of work done.  Ultra Low Volume (ULV) spraying does NO environmental damage.  Treatment strategy determined by entomological analysis.
  • 16. Integrated Malaria Management ULV Ground Fogging – mechanized and manual Ultra Low Volume (ULV) and aerosol ground fogging is common practice in places where malaria has been controlled. It serves to reduce mosquito populations in areas reached by insecticide sprays and limit malaria transmission. A variety of chemicals are used that are highly toxic to mosquitoes but safe for humans, animals and the environment. By varying the chemicals used build up of resistance is minimized.
  • 17. Integrated Malaria Management Treatment The need for malaria treatment is enormous ... over 400 million cases a year in Africa. But most do not get effective treatment. Public funding for programs is small, and most individuals do not have their own resources. Untreated malaria can be fatal. Use effective drugs. Avoid building up drug resistance.
  • 18. Integrated Malaria Management Insecticide Treated Bednets (ITN) Insecticide treated bednets (ITN) help reduce malaria transmission. They reduce contact with malaria infected mosquitoes and reduce malaria among people using bednets. But what about protection outside the house? Widespread bednet use requires a lot of effort and bednets are expensive relative to local incomes. ITN is a valuable part of a total solution, but only a part. ITN cannot achieve full success on its own.
  • 19. Integrated Malaria Management Examples of success Success in the early The Panama Canal Zone around 1904. part of the 20th Century Most of temperate Europe ended malaria largely by improved environment that reduced vector. Immediate post WW2 USA eliminated endemic malaria era to around 1960 Japan almost totally reduced malaria (heavy use of DDT) Italy and lastly Sardinia reduced malaria India had major reduction in malaria prevalence Considerable reduction in Caribbean locations Considerable reduction in Latin America Australia eliminated endemic malaria Recent experience in South Africa, Swaziland and Mozambique used Africa regional control and IRS (including use of DDT) to reduce malaria epidemic arising after about 10 years of no DDT use.

Notas del editor

  1. The purpose of this presentation is to describe the various interventions that comprise a comprehensive, integrated mosquito and malaria control (IMMC) program.
  2. Tr-Ac-Net (Peter Burgess) has collected a lot of material from peer reviewed papers about the costs of various interventions, but the information is, by good cost accounting standards, rather weak and not at all clear The reference material is listed in a “reference” file. Many of the authors of the papers have been contacted for clarification and guidance ... and an encouraging number of authors have shown interest in the IMMC Consortium initiative.
  3. Aerial treatment is very cost effective when the operations are used optimally. Work done is fast, and results can be significant. But operations need to be driven by good data, good analysis and good science. Aerial operations can do work in areas that cannot be reached easily on the ground ... marshy areas and informal shantytown areas with limited road access. Very low volumes of insecticide are used ... ultra low volume (ULV) droplets are tiny and kill mosquitoes while they are flying. The residue may never actually reach the ground. Other techniques such as larvaciding are effective when applied precisely where needed ... this requires good data and equipment such as GPS gear to operate with precision.
  4. This is just an introduction. More information is available in a variety of formats including pdf files, spreadsheet versions and presentation files. Generally speaking this material is available free to members of the Transparency and Accountability Network (Tr-Ac-Net Inc.) a not for profit corporation incorporated in Vermont USA. Contact Tr-Ac-Net ( [email_address] or www.tr-ac-net.org ) about becoming a member. The major theme of Tr-Ac-Net information is the critical value of management information, the decision making process and accounting and accountability. Another recurrent theme is the importance of value adding activities in socio-economic progress, and the profile of the value chains so that there is reasonable equity between all the legitimate stakeholders.