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A non-inferiority test is carried out to compare a new drug that comes with a claim of fewer side effects to the existing standard of care drug for shoulder injuries. Two comparisons of efficacy are done: a. The first efficacy comparison is on how quickly complete motor function is restored (Fewer number of days=better). Given a pre-specified margin of acceptance of 2 days, which of the following confidence intervals (point estimate: mean number of days for new drug - mean number of days for standard drug) would lead you to consider the new drug non-inferior to the standard? Briefly explain and select all that apply. i. (-5,-3) ii. (-5,0) iii. (0,3) iv. (-3,4) b. The second efficacy comparison is on a motor activity assessment scale from 0 to 100 (higher=better). Given a pre-specified margin of acceptance of 10 units, which of the following confidence intervals (point estimate: mean activity assessment for new drug - mean activity assessment for standard drug) would lead you to consider the new drug non-inferior to the standard? Briefly explain and select all that apply. i. (-18,-11) ii. (-11, 20) iii. (2, 20) iv. (-9,-3).

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A linked list is a linear data structure consisting of a set of nodes, where each one except the last points to the next node in the list. (Appendix A provides more information about linked lists.) Suppose we have the set of five nodes shown in the illustration on page 294. These nodes have been scrambled up and placed in a MARIE program as show below. Write a MARIE program to traverse the list and print the data in th order it is stored in each node. Address (Hex) 00D | Addr, Hex ???? // Top of list pointer: // You fill in the address of Node1. 00E | Node2, Hex 0032 // Node's data is the character "2." 00F | Hex ???? // Address of Node3. 010 | Node4, Hex 0034 // Character "4." 011 | Hex ???? 012 | Node1, Hex 0031 // Character "1" 013 | Hex ???? 014 | Node3, Hex 0033 // Character "3" 015 | Hex ???? 016 | Node5, Hex 0035 // Character "5" 017 | Hex 0000 // Indicates terminal node..

A linked list is a linear data structure consisting of a set of node.pdf

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A large File F is transformed from host A to host B. There are N Layer 3 devices between them. Assuming the links are un-congested. if the size of each segment was S and the size of the header was h and the transmission rate for each link is R. write the equation (formula) of the total delay assuming that the propagation delay for each link is P & assuming each Layer 3 device uses store-and-forward packet switching.

A large File F is transformed from host A to host B. There are N Lay.pdf

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A kindergarten class has four left-handed children and eight right-handed children. Two children are selected without replacement for a shoe-tying lesson. Let X = the number who are left- handed. (a) The simple events in the sample space are {RR, RL, LR, LL}. For instance, one simple event is RL, indicating that the first child is right-handed and the second one is left- handed. Find the probability for each of the simple events in the sample space.

A kindergarten class has four left-handed children and eight right-h.pdf

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A Japanese businessman on his first visit to the United States was pleased to be invited to a U.S. executives home for cocktails. He arrived promptly at 7 p.m. The host introduced him to a small group of people, and then returned to the front door to greet others who were arriving. The Japanese businessman seemed to have nothing to contribute on the seemingly mindless topics that were discussed. After a few minutes, the others in the group wandered off.

A Japanese businessman on his first visit to the United States was p.pdf

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A group researching the most popular college majors found that 19.3% of seniors in America study business. A large company's job recruiter sends emails sequentially to randomly selected US seniors who study business. (a) Find the expected number of emails the recruiter has to send before emailing a senior who is studying business? (b) Find the probability of the first senior studying business is contacted with the tenth email?.

A group researching the most popular college majors found that 19.3.pdf

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a ground-glass appearance and air bronchogram on the chest X-ray. Finally, because the baby Pao2 was less than 45 torr shortly after birth, the ductus arteriosus remained patent, producing the syndrome known as persistent pulmonary hypertension of the neonate (PPHN). As the infant's condition improved and his PaO2 increased, the ductus arteriosus closed and the signs and symptoms associated with PPHN disappeared. At the time of this writing, the baby was a perfectly normal 3 year-old boy who was attending half-day preschool sessions 5 days per week. 1. In this case, what are the major anatomic alterations of the lung associated with the respiratory disease that developed in the infant? 2. Describe the pathophysiology that develops as the conditions listed in question 1 worsen. 3. Describe how the following conditions are manifested in the clinical setting: Decreased pulmonary diffusion: Decreased lung compliance: 4. Why did PPHN develop in the infant in this case? How did this condition improve? Discussion This case illustrater the possible adverse effects of a premature birth on the infant's alveolar-apillary gas exchange units and pulmonary circulation. During fetal development, the alveolar-capillary system and the quantity of pulmonary surfactant usually are not sufficient to support life until the 28th week of gestation or beyond. In this case, the baby was born at the very beginning of this time period. Thus, because of the immaturity of the baby's alveolar- capilary system, the ability of the type II cells to produce pulmonary surfactant was inadequate. As a result of the insufficient amount of pulmonary surfactant, the pathologic processes of a common newborn respiratory disorder called respiratory distress syndrome (RDS) developed. The anatomic alterations of the lungs associated with RDS indude interstitial and intra-alveolar edema and hemorrhage, alveolar consoldation, intra-alveolar hyaline membrane formation, and atelectasis. All of these pathologic processes cause the alveolar-capillary membranes thickness to increase. As this condtion progressively worsened, the diffusion of oxygen between the alveoli and the pulmonary capillary blood decreased, and the infant's lung compliance decreased. Clinically, the decreased diffusion of oxygen was manifested by cyanosis, increased respiration rate and heart rate, and decreased Pa. The decreased lung compliance was manifested by nasal flaring, intercostal retractions, exhalation grunting, bilateral crackles, and.

a ground-glass appearance and air bronchogram on the chest X-ray.F.pdf

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A fines de enero, Mineral Labs tena un inventario de 875 unidades, cuya produccin costaba $10 por unidad. Durante febrero, la empresa produjo 1400 unidades a un costo de $14 por unidad. a. Si la empresa vendi 1850 unidades en febrero, cul fue el costo de los bienes vendidos? (Suponga contabilidad de inventario LIFO.) b. Si la empresa vendi 1850 unidades en febrero, cul fue el costo de los bienes vendidos? (Suponga que la contabilidad de inventario FIFO.).

A fines de enero, Mineral Labs ten�a un inventario de 875 unidades, .pdf

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A database is a shared, integrated computer structure that stores a collection of: end-user data, or raw facts of interest to the end user metadata, or data about data, through which the end-user data are integrated and managed A database management system (DBMS) is a collection of programs that manages the database structure and controls access to the data stored in the database. 1.1 List and explain different types of databases according to their categories..

A database is a shared, integrated computer structure that stores a .pdf

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A Duke le pareca que Lucinda Furtado, una asistente de limpieza, de alguna manera era un vnculo con las preocupaciones sobre la moral del personal. Lucinda, una inmigrante de Filipinas, haba estado trabajando en el hotel durante diez aos, pero se estaba convirtiendo en un problema para sus supervisores y compaeros de trabajo. Lucinda actu de maneras que parecan socavar a sus supervisores y compaeros de trabajo: se haban usado los trminos abusivo y acoso sobre ella. Desarroll la reputacin de ser una "entrometida" al rastrear el trabajo de otros empleados hasta el punto de dejar su propia estacin de trabajo para preguntar a otros empleados sobre sus cargas de trabajo en comparacin con su propia carga de trabajo. Tambin se hizo conocida por otros comportamientos no productivos, como hacer comentarios mezquinos hacia los empleados que "trabajan ms". Ella enviaba mensajes sutiles pero claros sobre el resto del personal, por ejemplo, cambiando obviamente su idioma en medio de las conversaciones cuando ciertas amas de llaves ingresaban a la sala de profesores. Habra quedado bastante claro para el resto del personal que Lucinda haba estado hablando de ellos. Gran parte de sus acciones negativas fueron individuales, a menudo difundiendo rumores sobre otros miembros del personal o sobre el hotel mismo. Durante el perodo en que Duke ocup el cargo de gerente general, l y el gerente de recursos humanos del hotel se haban reunido con Lucinda seis veces para conversaciones documentadas sobre el desempeo. Cuando se discuti su comportamiento, su reaccin tpica fue reclamar "mi error, no lo que quise decir, perdn por causar este problema". Furtado tambin dio a entender que las diferencias culturales fueron la razn del malentendido; las discusiones sobre el desempeo siguieron el mismo patrn. Lucinda aleg un malentendido, jur que su intencin era buena y mencion otras cuestiones no relacionadas. Lucinda a menudo estaba en el centro de las disputas de horarios de trabajo, lo que inevitablemente condujo a sus reclamos de racismo hacia ella por parte de la gerencia y el consiguiente trato injusto. Lucinda revisaba regularmente las asignaciones de habitaciones en los portapapeles de otros empleados que estaban almacenados en sus carritos de servicio. Los portapapeles indicaban el nmero de estancias y salidas y Lucinda quera verificar para asegurarse de que no se le asign un "nmero injusto de salidas". Lucinda se asegur de que la programacin del trabajo siempre causara drama y dejara a su supervisora, la ama de llaves ejecutiva, siempre preguntndose qu iba a pasar a continuacin. Una queja tpica era que no la trataban de manera justa cuando haba solicitado das libres. En un caso, dos amas de llaves haban pedido das libres el mismo da. Me haban explicado que eran flexibles con las fechas. Su supervisora, la ama de llaves ejecutiva, permiti que ocurriera esta situacin porque la ocupacin del hotel en ese da en particular era baja y su ausencia no tendra un impacto negativo.

A Duke le parec�a que Lucinda Furtado, una asistente de limpieza, .pdf

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A database is a collection of data that is organized in a way to allow users to retrieve and use. It is often referred to as an electronic filing system. Database design is the process of creating a model of the database. The model can include a number of attributes and entities, including users, logic, physical storage locations, and relationships. If you had to explain how database design can impact data architecture, what would you say? What example would you use to demonstrate or establish your explanation?.

A database is a collection of data that is organized in a way to.pdf

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A dependency diagram is given for a table. Please convert it to .pdf

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A El proceso de produccin de peridicos ha recorrido un largo camino desde los viejos tiempos cuando el peridico se escriba, editaba, compona y finalmente se imprima en un edificio con los periodistas trabajando en los pisos superiores y las imprentas en la planta baja. En estos das, es probable que el editor, los subeditores y los periodistas que elaboran el peridico se encuentren en un edificio totalmente diferente o incluso en una ciudad diferente. Esta es la situacin que ahora prevalece en Sydney. El diario se compila en la sede editorial, conocida como el centro de preimpresin, en el corazn de la ciudad, pero se imprime lejos en los suburbios en el centro de impresin. Aqu los seres humanos son una minora ya que gran parte del trabajo lo realizan mquinas automatizadas controladas por computadoras. B Una vez que se ha creado el peridico terminado para la edicin de la maana siguiente, todas las pginas se transmiten electrnicamente desde el centro de preimpresin al centro de impresin. El sistema de transmisin es una actualizacin del sofisticado sistema de facsmil de pginas que ya se utiliza en muchos otros peridicos. Un colocador de imgenes en el centro de impresin entrega las pginas como pelcula. Se tarda menos de un minuto en producir cada pgina, aunque para las pginas en color se envan cuatro versiones, una vez para cada una, para negro, cian, magenta y amarillo. Luego, las pginas se procesan en negativos fotogrficos y la pelcula se usa para producir planchas de impresin de aluminio listas para las prensas. C Una procesin de vehculos automatizados est ocupada en el nuevo centro de impresin donde se imprime el Sydney Morning Herald todos los das. Con luces intermitentes y bocinas de advertencia sonando, los robots (para darles su nombre correcto, los LGV o vehculos guiados por lser) lucen para todo el mundo como mquinas entusiastas de una pelcula de ciencia ficcin, mientras siguen sus propios caminos aleatorios alrededor de la planta. continuar con sus trabajos. La automatizacin de este tipo ahora es estndar en todas las plantas de peridicos modernas. Los robots pueden detectar personal no autorizado y alertar al personal de seguridad inmediatamente si encuentran un "intruso"; No es sorprendente que ya se cuenten cuentos fantsticos sobre las mquinas que comienzan a adquirir personalidades propias. D El trabajo principal de los robots, sin embargo, es cambiar el papel de peridico (el papel de impresin) que llega a la planta en bobinas enormes y emerge en el otro extremo algn tiempo despus como peridicos. Una vez que se determina el tamao del peridico del da y el orden de publicacin en la oficina central, la informacin se ingresa a la computadora y los LGV se programan para realizar su trabajo. Los LGV recogen las bobinas de papel del tamao adecuado y las llevan a donde tienen que ir. Cuando la prensa necesita otra bobina, su computadora alerta al sistema LGV. Los Sydney LGV se mueven afanosamente por la sala de prensa cumpliendo sus dos func.

A El proceso de producci�n de peri�dicos ha recorrido un largo c.pdf

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A exercise web tool powered by AI is currently under development here at the office. This software will keep tabs on how often and for how long its users exercise, as well as provide helpful reminders and pointers along the way.Provide a system architecture model (a visual representation of the planned layout of the system, along with a detailed explanation of its components) for the work to be done..

A exercise web tool powered by AI is currently under development her.pdf

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a distribution is given as X~ U(0,12)what is the probability d.pdf

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A detailed explanation for question C? thank you Assume the time T in between any two email messages arriving to an email server is an exponential random variable with distribution F1(t)=1e20t (where t is measured in minutes so that the arrival rate is 20 email messages per minute) a. [5 points] What is the probability that the next email arrives less than 3 seconds later? b. [ 5 points] What is the probability that the next email arrives after at least 1 second? c. [10 points] Consider the situation in which 1.

A detailed explanation for question Cthank you Assume.pdf

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A digital factory that is connected, networked, and fully integrated creates opportunities to minimize costs of downtime and underperformance in production and to enable the best output from factory assets and employees. What is a challenge that companies face when using digital manufacturing? Maintaining machinery and equipment using proactive real-time monitoring with a predictive maintenance model Maintaining machinery and equipment using proactive real-time monitoring with a predictive maintenance modelDecreasing manufacturing cycle times, which is the time required to produce an order Eliminating manufacturing traffic jams Implementing advanced technologies like these can be challenging for many IT departments.

A digital factory that is connected, networked, and fully integrated.pdf

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A difference between a benign tumor and malignant cancer is the following A difference between a benign tumor and malignant cancer is the following: Benign cells are frequently caused by viruses, while malignant cells are rerel, if ever. Benign tumor cells sill have control of the cell cycle, while malignant cells do not. Benign tumors are small, while malignant tumors can grow to be quite large. Benign cells do not leave the tumor to e stabblish new tumors, while malignant cells may. O Benign tumor cells generally do not have mutations, while malignant cels do..

A difference between a benign tumor and malignant cancer is the foll.pdf

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A developmental psychologist is interested in whether children (age 5 and 11 years) differ in their liking of jazz music. The psychologist studies 100 children at a local elementary school by having them listen to 3 different jazz songs and then, after hearing all three songs, asks them to rate whether they like that type of music or not (yes or no). Referring to Table 1, test whether liking jazz music depends on the age of the child using an alpha of 0.05 and all the steps in hypothesis testing.age of childrenLiking of Jazz Music511YES4226NO1814.

A developmental psychologist is interested in whether children (age .pdf

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A continuous random variable X has a density function given by Show that the area under the curve is equal to 1. Find P(2 < X < 2.5). Find P(X < 1.6) Find P(x< 1) Find P(x > 2) E(X), V(X), and E(X). E(3X +1), Var(3X + 1), and SD(3X + 1) Q7: A continuous random variable X has a density function given by f(x)={210,1x3otherwise i) Show that the area under the curve is equal to 1 . ii) Find P(22) vi) E(X),V(X), and E(X). vii) E(3X+1),Var(3X+1), and SD(3X+1).

A continuous random variable X has a density function given by.pdf

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A continuacin se presenta informacin relacionada con Hale Corporation al 31 de diciembre de 2017: Acciones comunes, $1 por $3,500,000 Capital pagado en exceso de la par: acciones comunes 550,000 Acciones preferentes al 8 1/2 %, $50 a la par 2 000 000 Capital pagado en exceso de la par: acciones preferentes 400,000 Utilidades retenidas 1,500,000 Acciones comunes del Tesoro (al costo) 150,000 Durante 2018, Hale Corporation registr las siguientes transacciones: emiti 500 acciones ordinarias por $9,500; re-emiti todas las acciones de tesorera por $140,000; ingresos netos reportados de $120,000; y pag dividendos en efectivo de 50.000. El capital contable total de Hale Corporation al 31 de diciembre de 2018 es?.

A continuaci�n se presenta informaci�n relacionada con Hale Corporat.pdf

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