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Unilateral Electroconvulsive Therapy in Rabbit Stroke Model: Evaluation Using SPECT  Deepak Agrawal, NK Gowda*, R Sagar**, PK Yadav***, Departments of Neurosurgery, Nuclear medicine*, Psychiatry** & Experimental Animal Facility*** All India Institute of Medical Sciences, New Delhi, India-110029
Background ,[object Object],[object Object]
Hypothesis ,[object Object]
AIMS & OBJECTIVES ,[object Object]
Why Rabbit Model ,[object Object],[object Object]
Why UECT? ,[object Object],[object Object],[object Object],[object Object]
Materials & Methods ,[object Object],[object Object],[object Object]
Materials & Methods ,[object Object],[object Object],[object Object],[object Object]
Materials & Methods ,[object Object],[object Object],[object Object],[object Object]
Materials & methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Materials & Methods ,[object Object]
Materials & Methods ,[object Object],[object Object]
Materials & Methods ,[object Object],[object Object]
Materials & Methods ,[object Object],[object Object],[object Object],[object Object],[object Object]
Materials & Methods ,[object Object],[object Object]
Materials & Methods ,[object Object],[object Object]
Materials & Methods ,[object Object],[object Object]
Materials & Methods ,[object Object]
STUDY DESIGN 5 RABBITS Rt ICA LIGATION SPECT Brain (50 min after stoke)  Randomised to UECT Gp (n=3) Randomised to Control Gp (n=2) Rt Sided UECT No ECT REPEAT SPECT (120 min after stroke) ANIMAL SACRIFIED
RESULTS ,[object Object],[object Object],[object Object]
RESULTS ,[object Object]
RESULTS ,[object Object],[object Object]
UECT GROUP PRE-UECT POST-UECT
RESULTS ,[object Object],[object Object]
LIMITATIONS ,[object Object],[object Object],[object Object]
CONCLUSIONS ,[object Object]
CONCLUSIONS ,[object Object],[object Object]
Thank You

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Unilateral electroconvulsive therapy_in_rabbit_stroke_model1

  • 1. Unilateral Electroconvulsive Therapy in Rabbit Stroke Model: Evaluation Using SPECT Deepak Agrawal, NK Gowda*, R Sagar**, PK Yadav***, Departments of Neurosurgery, Nuclear medicine*, Psychiatry** & Experimental Animal Facility*** All India Institute of Medical Sciences, New Delhi, India-110029
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  • 19. STUDY DESIGN 5 RABBITS Rt ICA LIGATION SPECT Brain (50 min after stoke) Randomised to UECT Gp (n=3) Randomised to Control Gp (n=2) Rt Sided UECT No ECT REPEAT SPECT (120 min after stroke) ANIMAL SACRIFIED
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  • 23. UECT GROUP PRE-UECT POST-UECT
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