1. MicroRNAs are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play important roles in skin biology and diseases. 2. Specific microRNAs like miR-203, miR-146a and miR-125b are involved in the pathogenesis of psoriasis by regulating inflammatory signaling pathways. 3. MicroRNAs also modulate processes like wound healing, angiogenesis, and skin cancer development by targeting genes involved in these processes. Dysregulation of microRNAs has been observed in melanoma and other skin malignancies.