How to use technology to improve data integrity.pptx
1. How to use technology to
improve data integrity
Hesham Al-Inany, M.D, PhD
2. • Introduction
• Past
• Future
• Before
• During
• After
• Kasr El-Aini model
• Conclusion
Outline
3. Introduction
• The Lancet MMR autism fraud, a 1998 study that falsely claimed a link
between the measles, mumps, and rubella (MMR)
vaccine and autism.
• Publicity around the 1998 study caused a sharp decline in vaccination
uptake, leading to a number of outbreaks of measles around the
world.
• undisclosed financial conflicts of interest on P.I part. to earn up to
$43 million per year selling test kits
• was struck off the medical register
16. During conducting the trial
• Monitoring the progress
• RedCap software
• Avoid data falsification
17. But
• RedCap software for universities & academic centers
• Mainly for projects but can be applied to research papers
• Free but u have to get access from university admin
• Alternative is Google sheets
21. Preprint copy release
• Ivermectin paper scandal
• Research square platform
• detecting research misconduct
22. At time of publishing 2022
• It can be detected by statistical tools, like the chi-square test for
uniformity of digit distributions.
• check the “rightmost digits” of the collected data. The “rightmost
digit” is the digit that a number ends in. It is considered to be “the
most random digit of a number,” which means that that the numbers
that make up a data set should be uniformly distributed as in a lottery
23. Journals : Hi-Tech
• Detecting and preventing peer-review fraud
• ScholarOne Manuscripts includes a program to detect unusual
submission and peer review activity that may warrant further
investigation by the journal.
36. Lines of research : model of 1st trimester U/S
• Correlation of Maternal right ventricular function with the uteroplacental circulation in first trimester and
pregnancy outcome in women with congenital heart disease
• First trimester scan for the early detection of fetal structural anomalies: detection rates
• Fetal abnormalities associated with increased nuchal translucency versus cell-free fetal DNA
• Effectiveness of a 12-13 week scan for the early diagnosis of fetal congenital anomalies ( chromosomal and
structural )
• Caesarean scar pregnancy in first trimester, longitudinal study for detection of PAS rates
• Accuracy of Prenatal diagnosis of cardiac defects
• Increased hepatic artery flow in first early-second trimester fetuses with enlarged nuchal translucency
• Performance of the First trimester ultrasound signs of spina bifida , longitudinal study
• Fetal cranium normal and abnormal at 13 weeks
• Fetal face normal and abnormal at 13 weeks
39. Next steps
• Apply RedCap data entry for any Thesis
• Electronic archive of all thesis IPD
• Committee of Data Integrity ( Prof.Dr.AbdelHamid Attia)
40. Key : compulsory ?
• But help researchers
• Ensure facilities are available for them (unit for research
excellence)
• Save their time and money ( trained secretaries doing the job)