Los mamíferos son vertebrados cubiertos de pelo que dan a luz crías vivas a las que alimentan con leche de sus mamas, y se encuentran en todas las regiones del planeta.
Sexta parte sobre nuestro especial de biología. Analizaremos los primcipales grupos en que se subdividen los animales mamíferos.
Visite nuestro blog: http://pepascientificas.blogspot.com
Sexta parte sobre nuestro especial de biología. Analizaremos los primcipales grupos en que se subdividen los animales mamíferos.
Visite nuestro blog: http://pepascientificas.blogspot.com
Abstract
Background: Salt is an important component for normal function of cells. However, we consume more than 10 times the salt that is required. This high salt content affects the renin–angiotensin–aldosterone system (RAAS) that regulates blood pressure (BP) and water content of our body. Angiotensinogen is an oligopeptide hormone precursor serving as a substrate for renin in the formation of angiotensin I. Angiotensin I is converted to angiotensin II that causes vasoconstriction and a subsequent increase in BP. We hypothesized that angiotensinogen secretions increases in the kidney and urine with intake of high salt diet.
Methods: Dahl salt sensitive (SS) and salt resistant (SR) male rats (8 weeks old) were fed with high salt (HS) and low salt (LS) diet along with or without aldosterone (ALDO); aldosterone antagonist, eplerenone (EPL); and NADPH oxidase inhibitor, apocynin (APC) for 21 days. Urine samples and kidney were collected; total proteins isolated, and quantified using the microassay procedure and analyzed by western blot for angiotensinogen.
Results: Angiotensinogen was detected in the kidney samples of Dahl SS rat when fed either low or high salt diet, whereas angiotensinogen was detected in kidney samples of Dahl SR rats when fed with high salt diets. Angiotensinogen was not detected in urine samples.
Conclusions: In conclusion, consuming a high salt diet increases Angiotensinogen that lead to an increase in angiotensin II which may cause an increase in BP.
Acknowledgements: Vivien Thomas Summer Research Program, Morehouse School of Medicine, Atlanta, GA, USA.
1. 2 Los animales
29
Ciencias de la
Naturaleza
Mamíferos 1º ESO
Los mamíferos son vertebrados con el cuerpo cubierto de pelos, son vivíparos
y poseen mamas
Los mamíferos alimentan a sus crías
con la leche de sus mamas
Los mamíferos habitan en todas las
regiones del planeta
Cola
Tronco
Patas
Ojos
Pabellones
auditivos
Orificios
nasales