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by,
RAMESH.KASARLA
Pharm.D (PB 1st yr)
Roll no:3
1
INTRODUCTION
Gastroenteritis is an illness caused by infection and or
inflammation of he digestive tract. It is characterised
by nausea,vomiting,diarrhea and stomach cramps.
 The most common cause is a virus, which tends to
spread very easily. Less common causes of include
bacteria or food poisoning.
 An infection may be caused by bacteria or parasites in
spoiled food or unclean water.
2
CAUSES:
 Gastroenteritis has many causes. Viruses and bacteria
are the most common.
Bacteria: Escherichia coli, salmonella,compylobacter,
shigella.
Viruses: Adenoviruse, Rotaviruse, norovirus.
Parasites: Giardia - The most frequent cause of
waterborne diarrhea causing giardiasis.
 Cryptosporidium - Affects mostly people with
weakened immune systems, causes watery diarrhea
3
SUBJECTIVE:
 CHIEF COMPLAINT: - MR.KL, a 30 yrs old male patient
was admitted in hospital with complaint of fever with chills
since 3 days and abdominal pain associated with loose stools
since 3days.
 HISTORY OF PRESENT ILLNESS: - The patient was
presented with vomitings and fever associated with chills.
4
OBJECTIVE: -
 ALLERGIES: - No known drug allergy.
 PHYSICAL EXAMINATION:
 GENERAL APPEARANCE: -
 Height -175cm
 weight – 71.2kg
 BMI -23.4
 Vital signs:-
Pulse: - 72beats/minute.
RR:-22breaths/minute.
BP: - 110/80 mm of Hg.
Temperature: - Afebrile.
Pain: - 0/10
5
LABORATORY INESTIGATIONS
complete blood count
6
TEST RESULT REFERENCE VALUE
Hemoglobin 17.5* 12-16g/dl
Hematocrit 52.3 45-55
RBC 5.25 3.7-5.6million/mm3
MCV 100* 75-95fl
MCH 33.49* 26-32
Platelets 380 140-440 x 103/ mm3
Neutrophils 56% 40-75%
Llymphocytes 26% 20-45%
Eosinophils 16%* 1-10%
ESR 05 0-10
ELECTROLYTES:
RENAL FUNCTION TESTS:
7
TEST RESULT REFERENCE VALUE
Na+ 132* 135-145mmol/dL
K+ 3.4* 3.5-4.5mmol/dL
Cl‫־‬
95* 98-107mmol/dL
TEST RESULT REFERENCE VALUE
Urea 48* 15-38
Serum creatinine 1.0 0.5-1.2
BUN 22* 7-18
Globulin 3.7* 1.8-3.6
Prealbumin 15* 19.5-35.8
Malarial anigen detection test: negative
CBC with ESR- negative
Ultrasound whole abdomen-negative
Peripheral smear:
 RBC: Normocytic, normochromic
 WBC: monocytosis
 Platelets: adequate on smear
DIAGNOSIS: Chronic gastroenteritis
8
DRUG CHART
DRUG NAME GENERIC NAME DOSE ROUTE FREQENCY INDICATION
Inj.NEKSIUM esomeprazole 40mg IV OD Gasrtitis
Inj.ZOFER ondansetron 8mg IV TID Vomiting
Inj.ZANOCIN ofloxacin 200mg IV BID Antibiotic
IVF.DNS Normal saline 100ml/hr IV Hydration
C.DAROLAC lactobacillus 1 cap PO TID Probiotic
C.REDOTIL racecadotril 1cap PO TID Diarrhea
C.RIFAGUT rifaximin 400mg PO BD Diarrhea.
9
ASSESSMENT:
MR.KL 30yr old male patien was admitted in hospital
with complains of fever with chills since 3 days and abdominal
pain associated with loose stools since 3days.
VOMITING AND DIARRHOEA: Antiemitics ONDANSETRON,
antidiarrhoeal RACECADOTRIL and
RIFAGUT was given and probiotic (T.DOROLAC) which
normalizes the presence of intestinal flora.
HYDRATION: the patient was hydrated by administering
IVF.DNS.
GASTRITIS:INJ.NEKSIUM(esomeprazole) was given for gastritis.
ANTIBIOTIC:INJ.ZANOCIN(ofloxacin) was given as antibiotic.
10
PLAN:
RECOMMENDATIONS:
 Check the vital signs
 Check and monitor the electrolyte levels and renal function
tests
 Strictly monitor urine input-output levels
 Avoid giving fruit juices and carbonated drinks until the
diarrhoea has stopped
 Drink plenty of fluids. An electrolyte replenisher or
rehydration liquid may be helpful.
 After diarrhea and vomiting stop, drink small amounts of
clear liquid such as tea and flat ginger ale or lemon/lime
soda.
 After tolerating soft food for two or three days, gradually
return to a normal diet.
11
DISCHARGE MEDICATIONS:
 T.ZOFER(ondansetron)-4mg per oral if necessary for
vomiting.
 C.DAROLAC(lactobacillus)-1 cap per oral,three
times a day as probiotic.
 C.REDOTIL(racecadotril)-1 cap per oral, three times
a day if necessary for diarrhea.
12
THANK YOU
13

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Chronic gastroenteritis case prasentation

  • 2. INTRODUCTION Gastroenteritis is an illness caused by infection and or inflammation of he digestive tract. It is characterised by nausea,vomiting,diarrhea and stomach cramps.  The most common cause is a virus, which tends to spread very easily. Less common causes of include bacteria or food poisoning.  An infection may be caused by bacteria or parasites in spoiled food or unclean water. 2
  • 3. CAUSES:  Gastroenteritis has many causes. Viruses and bacteria are the most common. Bacteria: Escherichia coli, salmonella,compylobacter, shigella. Viruses: Adenoviruse, Rotaviruse, norovirus. Parasites: Giardia - The most frequent cause of waterborne diarrhea causing giardiasis.  Cryptosporidium - Affects mostly people with weakened immune systems, causes watery diarrhea 3
  • 4. SUBJECTIVE:  CHIEF COMPLAINT: - MR.KL, a 30 yrs old male patient was admitted in hospital with complaint of fever with chills since 3 days and abdominal pain associated with loose stools since 3days.  HISTORY OF PRESENT ILLNESS: - The patient was presented with vomitings and fever associated with chills. 4
  • 5. OBJECTIVE: -  ALLERGIES: - No known drug allergy.  PHYSICAL EXAMINATION:  GENERAL APPEARANCE: -  Height -175cm  weight – 71.2kg  BMI -23.4  Vital signs:- Pulse: - 72beats/minute. RR:-22breaths/minute. BP: - 110/80 mm of Hg. Temperature: - Afebrile. Pain: - 0/10 5
  • 6. LABORATORY INESTIGATIONS complete blood count 6 TEST RESULT REFERENCE VALUE Hemoglobin 17.5* 12-16g/dl Hematocrit 52.3 45-55 RBC 5.25 3.7-5.6million/mm3 MCV 100* 75-95fl MCH 33.49* 26-32 Platelets 380 140-440 x 103/ mm3 Neutrophils 56% 40-75% Llymphocytes 26% 20-45% Eosinophils 16%* 1-10% ESR 05 0-10
  • 7. ELECTROLYTES: RENAL FUNCTION TESTS: 7 TEST RESULT REFERENCE VALUE Na+ 132* 135-145mmol/dL K+ 3.4* 3.5-4.5mmol/dL Cl‫־‬ 95* 98-107mmol/dL TEST RESULT REFERENCE VALUE Urea 48* 15-38 Serum creatinine 1.0 0.5-1.2 BUN 22* 7-18 Globulin 3.7* 1.8-3.6 Prealbumin 15* 19.5-35.8
  • 8. Malarial anigen detection test: negative CBC with ESR- negative Ultrasound whole abdomen-negative Peripheral smear:  RBC: Normocytic, normochromic  WBC: monocytosis  Platelets: adequate on smear DIAGNOSIS: Chronic gastroenteritis 8
  • 9. DRUG CHART DRUG NAME GENERIC NAME DOSE ROUTE FREQENCY INDICATION Inj.NEKSIUM esomeprazole 40mg IV OD Gasrtitis Inj.ZOFER ondansetron 8mg IV TID Vomiting Inj.ZANOCIN ofloxacin 200mg IV BID Antibiotic IVF.DNS Normal saline 100ml/hr IV Hydration C.DAROLAC lactobacillus 1 cap PO TID Probiotic C.REDOTIL racecadotril 1cap PO TID Diarrhea C.RIFAGUT rifaximin 400mg PO BD Diarrhea. 9
  • 10. ASSESSMENT: MR.KL 30yr old male patien was admitted in hospital with complains of fever with chills since 3 days and abdominal pain associated with loose stools since 3days. VOMITING AND DIARRHOEA: Antiemitics ONDANSETRON, antidiarrhoeal RACECADOTRIL and RIFAGUT was given and probiotic (T.DOROLAC) which normalizes the presence of intestinal flora. HYDRATION: the patient was hydrated by administering IVF.DNS. GASTRITIS:INJ.NEKSIUM(esomeprazole) was given for gastritis. ANTIBIOTIC:INJ.ZANOCIN(ofloxacin) was given as antibiotic. 10
  • 11. PLAN: RECOMMENDATIONS:  Check the vital signs  Check and monitor the electrolyte levels and renal function tests  Strictly monitor urine input-output levels  Avoid giving fruit juices and carbonated drinks until the diarrhoea has stopped  Drink plenty of fluids. An electrolyte replenisher or rehydration liquid may be helpful.  After diarrhea and vomiting stop, drink small amounts of clear liquid such as tea and flat ginger ale or lemon/lime soda.  After tolerating soft food for two or three days, gradually return to a normal diet. 11
  • 12. DISCHARGE MEDICATIONS:  T.ZOFER(ondansetron)-4mg per oral if necessary for vomiting.  C.DAROLAC(lactobacillus)-1 cap per oral,three times a day as probiotic.  C.REDOTIL(racecadotril)-1 cap per oral, three times a day if necessary for diarrhea. 12