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OB
Jeff Rundio D.O.
Arrowhead Regional Medical Center

1-8-14

Adapted from Intensive Review for the Emergency Medicine
Qualifying Examination
Physiologic changes in pregnancy
 Cardiovascular system
 Increased cardiac output
 Blood volume increases
 Resting hear rate increases by 10-15bpm
 SVR increases

 Decreased BP in 1st trimester
 Diastolic falls more than systolic
 Left lateral decubitus positioning may relieve hypotension
 Uterus places pressure on the IVC and decreases blood
return to the heart
Physiologic changes in pregnancy
 Respiratory system
 Increased tidal volume but decreased FRC because of
elevated diaphragm
 Minute ventilation increases this leads to respiratory alkalosis
 However, RR remains mostly unchanged
Physiologic changes in pregnancy
 Gastrointestinal system
 Gastric reflux is common secondary to delayed gastric
emptying, decreased lower esophageal sphincter tone and
decreased intestinal motility
 Increased risk of gallstones
Physiologic changes in pregnancy
 Renal-metabolic system
 Increased kidney size, renal blood flow and GFR
 Increased peripheral resistance to insulin
 Compensatory metabolic acidosis (to counteract the
respiratory alkalosis)

 In addition to relative insulin resistance, pregnant women
are more prone to DKA
Physiologic changes in pregnancy
 Hematopoietic system
 Hemoglobin decreases secondary to volume dilution
 Leukocyte count increases mildly although polymorph
leukocyte function is depressed beginning in the 2nd
trimester
 Coagulation factors and ESR increase
Diagnosis
 B-hCG
 Serum levels double about every two days in normal early
Pregnancy
 Failure to double suggests ectopic or nonviable
pregnancy
 Levels peak in 2-3 months and plateaus at 4 months
 Urine testing is sensitive at 20 mIU/mL and in serum at
10mIU/mL
 Can have false negative in dilute urine or early in
pregnancy
Diagnosis
 Ultrasound in ED used to rule in an IUP not rule out an ectopic
 Transabdominal U/S
 Gestational sac at 6 wks
 Yolk sac, fetal pole, fetal heart motion at 8 wks
 Transvaginal U/S
 Gestational sac at 5 wks: hCG 1000
 Yolk sac 6 wks :hCG 2500
 Fetal pole and heartbeat 7 to 8 wks: hCG 5000-17000
 Discriminatory zone: B-hCG level above which an IUP can confidently be
expected to be apparent on US
 Transvaginal level is 1500
 Transabdominal is 6000
 After abortion B-hCG levels may take up to 2 months to return to
negative
Complications of Pregnancy
 Vaginal bleeding in pregnancy
 Abortion
 Loss of pregnancy <20 wks or <500g
 About 30% of pregnancies abort spontaneously
 Usually 2/2 chromosomal abnormalities

 Risk increases with increasing maternal age, toxin
exposure, smoking, ETOH, cocaine), multiparous women,
endocrine and autoimmune disorders
Complications in Pregnancy
 Types of abortions
 Threatened ab: vaginal bleeding with closed os
 Inevitable ab: vaginal bleeding with open os
 Incomplete ab: passage of parts of POC
 Complete ab: passage of all fetal tissue

 Missed ab: fetal death <20wks without passage of fetal tissue
Complications in Pregnancy
 Management of abortions
 Threatened ab: DC with close follow up
 Incomplete ab: Uterine evacuation
 Complete ab: DC with close follow up
 Missed ab: D&C if infection or POC > 4wks otherwise, DC
with close follow up
 RhoGAM for all Rh-neg women
 Must be given within 72hrs of fetal blood exposure
 Dose 50mcg if <12wks
 Otherwise 300mcg
Ectopic Pregnancy
 Extra uterine implantation of pregnancy
 Risk factors
 PID
 Tubal surgery
 Prior ectopic
 IUD
 In vitro fertilization
Ectopic Pregnancy
 Signs and symptoms
 Classic triad of vaginal bleeding, abdominal pain and
pregnant/amenorrhea
 May have a relative bradycardia 2/2 vagal effects
 May have no vaginal bleeding

 May have a normal pelvic exam
Ectopic Pregnancy
 Diagnosis
 hCG
 Levels will likely decrease or not rise normally
 US findings suggestive of ectopic
 Ectoopic fetal heart beat

 Free fluid and absent IUP
 Adenxal mass and absent IUP
 US should be done despite low hCG levels
Ectopic Pregnancy
 Management
 Surgical
 Medical
 methotrexate
Abruptio placentae
 Separation of the placenta from the uterine wall
 Signs and symptoms
 PAINFUL vaginal bleeding
 But bleeding not always present
 Uterine tenderness
 Uterine contractions
 Rising fundus (indicates active bleeding)
 Fetal distress
Abruptio placentae
 Diagnosis
 Based on clinical suspicion
 US not great because blood and placenta look similar
 50% will have coagulopathy on labs

 Management
 IV fluids
 FFP as needed
 Emergent OB consult
 Emergent delivery if fetus or mother in distress
Placenta Previa
 Implantation of placenta over cervical os
 Signs and symptoms
 PAINLESS bright red vaginal bleeding

 Diagnosis
 Transvaginal US
 Never perform digital or speculum exam if suspected

 Management
 Stabilize mother
 Fetal monitoring
 Emergent OB consult
How was Chuck Norris Born?
How was Chuck Norris Born?
Uterine Rupture
 Becoming more common 2/2 VBAC still less than 1%
 Sudden pain and termination of contractions, tearing
sensation, vaginal bleeding
 Management, C-section
Preeclampsia
 Hypertension (sbp >140) and proteinuria >20 wks
gestation +/- pedal edema
 Headache, visual changes, edema and/or abdominal
pain
 May occur up to 6 weeks partum
 Becomes eclampsia when seizures occur
 Management mag sulfate 4 to 6 grams
 Follow DTRs
Postpartum Complications
 Retained POC
 May cause post partum bleeding
 If causes infection, leads to pain, fever and discharge

 Diagnosis
 Clinical suspicion and diagnosis
 US

 Management
 Supportive

 Removal of POC by D&C
Endometritis
 Inflammation of the uterine endometrium
 Acute endometritis caused by S. aureus or Strep infections

 Develop fever, foul smelling discharge, abdominal pain
 Diagnosis by Clinical suspicion, obtain US to r/o retained
POC

 Management
 Supportive
 IV ABX
 Clindamycin and Aminoglycoside or
 2nd or 3rd generation cephalosporin
Mastitis
 Inflammation of mammary gland
 Must distinguish cellulitis from abscess
 Management
 Anti-staph PCN (dicloxacillin)

 Cephlasporin
 Warm compresses
 Continue nursing
Medications in pregnancy
 Tylenol is safe
 ABX
 Sulfonamides: near term, may cause kernicterus
 Aminoglycocide: ototoxicity and renal tox
 Tetracyline: maternal- liver disease. Fetus- yellow discoloration of
teeth and other congenital defects
 Quinolones: musculoskeletal dysfunction (tendons)
 Fluconazole: craniofacial bone abnormalities

 Antihistamines are safe except for meclizine in 1st trimester
 Oral hypoglycemics are unsafe, but insulin is safe
The END

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Jeff Rundio, DO- OB Board Review 2014 - ARMC Emergency Medicine

  • 1. OB Jeff Rundio D.O. Arrowhead Regional Medical Center 1-8-14 Adapted from Intensive Review for the Emergency Medicine Qualifying Examination
  • 2. Physiologic changes in pregnancy  Cardiovascular system  Increased cardiac output  Blood volume increases  Resting hear rate increases by 10-15bpm  SVR increases  Decreased BP in 1st trimester  Diastolic falls more than systolic  Left lateral decubitus positioning may relieve hypotension  Uterus places pressure on the IVC and decreases blood return to the heart
  • 3. Physiologic changes in pregnancy  Respiratory system  Increased tidal volume but decreased FRC because of elevated diaphragm  Minute ventilation increases this leads to respiratory alkalosis  However, RR remains mostly unchanged
  • 4. Physiologic changes in pregnancy  Gastrointestinal system  Gastric reflux is common secondary to delayed gastric emptying, decreased lower esophageal sphincter tone and decreased intestinal motility  Increased risk of gallstones
  • 5. Physiologic changes in pregnancy  Renal-metabolic system  Increased kidney size, renal blood flow and GFR  Increased peripheral resistance to insulin  Compensatory metabolic acidosis (to counteract the respiratory alkalosis)  In addition to relative insulin resistance, pregnant women are more prone to DKA
  • 6. Physiologic changes in pregnancy  Hematopoietic system  Hemoglobin decreases secondary to volume dilution  Leukocyte count increases mildly although polymorph leukocyte function is depressed beginning in the 2nd trimester  Coagulation factors and ESR increase
  • 7. Diagnosis  B-hCG  Serum levels double about every two days in normal early Pregnancy  Failure to double suggests ectopic or nonviable pregnancy  Levels peak in 2-3 months and plateaus at 4 months  Urine testing is sensitive at 20 mIU/mL and in serum at 10mIU/mL  Can have false negative in dilute urine or early in pregnancy
  • 8. Diagnosis  Ultrasound in ED used to rule in an IUP not rule out an ectopic  Transabdominal U/S  Gestational sac at 6 wks  Yolk sac, fetal pole, fetal heart motion at 8 wks  Transvaginal U/S  Gestational sac at 5 wks: hCG 1000  Yolk sac 6 wks :hCG 2500  Fetal pole and heartbeat 7 to 8 wks: hCG 5000-17000  Discriminatory zone: B-hCG level above which an IUP can confidently be expected to be apparent on US  Transvaginal level is 1500  Transabdominal is 6000  After abortion B-hCG levels may take up to 2 months to return to negative
  • 9. Complications of Pregnancy  Vaginal bleeding in pregnancy  Abortion  Loss of pregnancy <20 wks or <500g  About 30% of pregnancies abort spontaneously  Usually 2/2 chromosomal abnormalities  Risk increases with increasing maternal age, toxin exposure, smoking, ETOH, cocaine), multiparous women, endocrine and autoimmune disorders
  • 10. Complications in Pregnancy  Types of abortions  Threatened ab: vaginal bleeding with closed os  Inevitable ab: vaginal bleeding with open os  Incomplete ab: passage of parts of POC  Complete ab: passage of all fetal tissue  Missed ab: fetal death <20wks without passage of fetal tissue
  • 11. Complications in Pregnancy  Management of abortions  Threatened ab: DC with close follow up  Incomplete ab: Uterine evacuation  Complete ab: DC with close follow up  Missed ab: D&C if infection or POC > 4wks otherwise, DC with close follow up  RhoGAM for all Rh-neg women  Must be given within 72hrs of fetal blood exposure  Dose 50mcg if <12wks  Otherwise 300mcg
  • 12. Ectopic Pregnancy  Extra uterine implantation of pregnancy  Risk factors  PID  Tubal surgery  Prior ectopic  IUD  In vitro fertilization
  • 13. Ectopic Pregnancy  Signs and symptoms  Classic triad of vaginal bleeding, abdominal pain and pregnant/amenorrhea  May have a relative bradycardia 2/2 vagal effects  May have no vaginal bleeding  May have a normal pelvic exam
  • 14. Ectopic Pregnancy  Diagnosis  hCG  Levels will likely decrease or not rise normally  US findings suggestive of ectopic  Ectoopic fetal heart beat  Free fluid and absent IUP  Adenxal mass and absent IUP  US should be done despite low hCG levels
  • 15. Ectopic Pregnancy  Management  Surgical  Medical  methotrexate
  • 16. Abruptio placentae  Separation of the placenta from the uterine wall  Signs and symptoms  PAINFUL vaginal bleeding  But bleeding not always present  Uterine tenderness  Uterine contractions  Rising fundus (indicates active bleeding)  Fetal distress
  • 17. Abruptio placentae  Diagnosis  Based on clinical suspicion  US not great because blood and placenta look similar  50% will have coagulopathy on labs  Management  IV fluids  FFP as needed  Emergent OB consult  Emergent delivery if fetus or mother in distress
  • 18. Placenta Previa  Implantation of placenta over cervical os  Signs and symptoms  PAINLESS bright red vaginal bleeding  Diagnosis  Transvaginal US  Never perform digital or speculum exam if suspected  Management  Stabilize mother  Fetal monitoring  Emergent OB consult
  • 19. How was Chuck Norris Born?
  • 20. How was Chuck Norris Born?
  • 21. Uterine Rupture  Becoming more common 2/2 VBAC still less than 1%  Sudden pain and termination of contractions, tearing sensation, vaginal bleeding  Management, C-section
  • 22. Preeclampsia  Hypertension (sbp >140) and proteinuria >20 wks gestation +/- pedal edema  Headache, visual changes, edema and/or abdominal pain  May occur up to 6 weeks partum  Becomes eclampsia when seizures occur  Management mag sulfate 4 to 6 grams  Follow DTRs
  • 23. Postpartum Complications  Retained POC  May cause post partum bleeding  If causes infection, leads to pain, fever and discharge  Diagnosis  Clinical suspicion and diagnosis  US  Management  Supportive  Removal of POC by D&C
  • 24. Endometritis  Inflammation of the uterine endometrium  Acute endometritis caused by S. aureus or Strep infections  Develop fever, foul smelling discharge, abdominal pain  Diagnosis by Clinical suspicion, obtain US to r/o retained POC  Management  Supportive  IV ABX  Clindamycin and Aminoglycoside or  2nd or 3rd generation cephalosporin
  • 25. Mastitis  Inflammation of mammary gland  Must distinguish cellulitis from abscess  Management  Anti-staph PCN (dicloxacillin)  Cephlasporin  Warm compresses  Continue nursing
  • 26. Medications in pregnancy  Tylenol is safe  ABX  Sulfonamides: near term, may cause kernicterus  Aminoglycocide: ototoxicity and renal tox  Tetracyline: maternal- liver disease. Fetus- yellow discoloration of teeth and other congenital defects  Quinolones: musculoskeletal dysfunction (tendons)  Fluconazole: craniofacial bone abnormalities  Antihistamines are safe except for meclizine in 1st trimester  Oral hypoglycemics are unsafe, but insulin is safe