Jeff Rundio, DO- OB Board Review 2014 - ARMC Emergency Medicine
1. OB
Jeff Rundio D.O.
Arrowhead Regional Medical Center
1-8-14
Adapted from Intensive Review for the Emergency Medicine
Qualifying Examination
2. Physiologic changes in pregnancy
Cardiovascular system
Increased cardiac output
Blood volume increases
Resting hear rate increases by 10-15bpm
SVR increases
Decreased BP in 1st trimester
Diastolic falls more than systolic
Left lateral decubitus positioning may relieve hypotension
Uterus places pressure on the IVC and decreases blood
return to the heart
3. Physiologic changes in pregnancy
Respiratory system
Increased tidal volume but decreased FRC because of
elevated diaphragm
Minute ventilation increases this leads to respiratory alkalosis
However, RR remains mostly unchanged
4. Physiologic changes in pregnancy
Gastrointestinal system
Gastric reflux is common secondary to delayed gastric
emptying, decreased lower esophageal sphincter tone and
decreased intestinal motility
Increased risk of gallstones
5. Physiologic changes in pregnancy
Renal-metabolic system
Increased kidney size, renal blood flow and GFR
Increased peripheral resistance to insulin
Compensatory metabolic acidosis (to counteract the
respiratory alkalosis)
In addition to relative insulin resistance, pregnant women
are more prone to DKA
6. Physiologic changes in pregnancy
Hematopoietic system
Hemoglobin decreases secondary to volume dilution
Leukocyte count increases mildly although polymorph
leukocyte function is depressed beginning in the 2nd
trimester
Coagulation factors and ESR increase
7. Diagnosis
B-hCG
Serum levels double about every two days in normal early
Pregnancy
Failure to double suggests ectopic or nonviable
pregnancy
Levels peak in 2-3 months and plateaus at 4 months
Urine testing is sensitive at 20 mIU/mL and in serum at
10mIU/mL
Can have false negative in dilute urine or early in
pregnancy
8. Diagnosis
Ultrasound in ED used to rule in an IUP not rule out an ectopic
Transabdominal U/S
Gestational sac at 6 wks
Yolk sac, fetal pole, fetal heart motion at 8 wks
Transvaginal U/S
Gestational sac at 5 wks: hCG 1000
Yolk sac 6 wks :hCG 2500
Fetal pole and heartbeat 7 to 8 wks: hCG 5000-17000
Discriminatory zone: B-hCG level above which an IUP can confidently be
expected to be apparent on US
Transvaginal level is 1500
Transabdominal is 6000
After abortion B-hCG levels may take up to 2 months to return to
negative
9. Complications of Pregnancy
Vaginal bleeding in pregnancy
Abortion
Loss of pregnancy <20 wks or <500g
About 30% of pregnancies abort spontaneously
Usually 2/2 chromosomal abnormalities
Risk increases with increasing maternal age, toxin
exposure, smoking, ETOH, cocaine), multiparous women,
endocrine and autoimmune disorders
10. Complications in Pregnancy
Types of abortions
Threatened ab: vaginal bleeding with closed os
Inevitable ab: vaginal bleeding with open os
Incomplete ab: passage of parts of POC
Complete ab: passage of all fetal tissue
Missed ab: fetal death <20wks without passage of fetal tissue
11. Complications in Pregnancy
Management of abortions
Threatened ab: DC with close follow up
Incomplete ab: Uterine evacuation
Complete ab: DC with close follow up
Missed ab: D&C if infection or POC > 4wks otherwise, DC
with close follow up
RhoGAM for all Rh-neg women
Must be given within 72hrs of fetal blood exposure
Dose 50mcg if <12wks
Otherwise 300mcg
12. Ectopic Pregnancy
Extra uterine implantation of pregnancy
Risk factors
PID
Tubal surgery
Prior ectopic
IUD
In vitro fertilization
13. Ectopic Pregnancy
Signs and symptoms
Classic triad of vaginal bleeding, abdominal pain and
pregnant/amenorrhea
May have a relative bradycardia 2/2 vagal effects
May have no vaginal bleeding
May have a normal pelvic exam
14. Ectopic Pregnancy
Diagnosis
hCG
Levels will likely decrease or not rise normally
US findings suggestive of ectopic
Ectoopic fetal heart beat
Free fluid and absent IUP
Adenxal mass and absent IUP
US should be done despite low hCG levels
16. Abruptio placentae
Separation of the placenta from the uterine wall
Signs and symptoms
PAINFUL vaginal bleeding
But bleeding not always present
Uterine tenderness
Uterine contractions
Rising fundus (indicates active bleeding)
Fetal distress
17. Abruptio placentae
Diagnosis
Based on clinical suspicion
US not great because blood and placenta look similar
50% will have coagulopathy on labs
Management
IV fluids
FFP as needed
Emergent OB consult
Emergent delivery if fetus or mother in distress
18. Placenta Previa
Implantation of placenta over cervical os
Signs and symptoms
PAINLESS bright red vaginal bleeding
Diagnosis
Transvaginal US
Never perform digital or speculum exam if suspected
Management
Stabilize mother
Fetal monitoring
Emergent OB consult
21. Uterine Rupture
Becoming more common 2/2 VBAC still less than 1%
Sudden pain and termination of contractions, tearing
sensation, vaginal bleeding
Management, C-section
22. Preeclampsia
Hypertension (sbp >140) and proteinuria >20 wks
gestation +/- pedal edema
Headache, visual changes, edema and/or abdominal
pain
May occur up to 6 weeks partum
Becomes eclampsia when seizures occur
Management mag sulfate 4 to 6 grams
Follow DTRs
23. Postpartum Complications
Retained POC
May cause post partum bleeding
If causes infection, leads to pain, fever and discharge
Diagnosis
Clinical suspicion and diagnosis
US
Management
Supportive
Removal of POC by D&C
24. Endometritis
Inflammation of the uterine endometrium
Acute endometritis caused by S. aureus or Strep infections
Develop fever, foul smelling discharge, abdominal pain
Diagnosis by Clinical suspicion, obtain US to r/o retained
POC
Management
Supportive
IV ABX
Clindamycin and Aminoglycoside or
2nd or 3rd generation cephalosporin
25. Mastitis
Inflammation of mammary gland
Must distinguish cellulitis from abscess
Management
Anti-staph PCN (dicloxacillin)
Cephlasporin
Warm compresses
Continue nursing
26. Medications in pregnancy
Tylenol is safe
ABX
Sulfonamides: near term, may cause kernicterus
Aminoglycocide: ototoxicity and renal tox
Tetracyline: maternal- liver disease. Fetus- yellow discoloration of
teeth and other congenital defects
Quinolones: musculoskeletal dysfunction (tendons)
Fluconazole: craniofacial bone abnormalities
Antihistamines are safe except for meclizine in 1st trimester
Oral hypoglycemics are unsafe, but insulin is safe