7. LOCALIZADA: activaci ó n sistemas de la coagulaci ó n, quininas y fibrinol í tico SIST ÉMICA : fiebre, leucocitosis, s í ntesis esteroides y prote í nas de fase aguda
11. SEGUNDA LINEA DE DEFENSA SISTEMA INMUNE NATURAL O INNATO: Macr ófagos Linfocitos NK Sistema del Complemento Células presentadoras de antígenos (APCs)
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13. TERCERA LINEA DE DEFENSA SISTEMA INMUNE ADQUIRIDO Linfocitos B Linfocitos T Organos linfoides primarios y secundarios
14. ORGANIZACION FUNCIONAL Organos linfoides primarios desarrollo y maduraci ó n Organos linfoides secundarios captura de Ag encuentros Ag-Ac efectores ESTRUCTURAL Muchos ó rganos y tejidos diferentes
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17. CELULA PLURIPOTENCIAL PROGENITORA PROGENITORA LINFOIDE MIELOIDE (B, T, NK) ROJAS BLANCAS PLAQ . Según factores de crecimiento, microambiente HSC = 1 de cada 50,000 en médula ósea
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20. Reemplazo de un gene normal por un alelo mutante o una forma alterada del gene: ratones transg é nicos (si lo lleva) ratones knockout (si le falta)
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25. bcl-2 previene apoptosis: aumenta susceptibilidad Activaci ó n de B disminuye bcl-2 y aumenta receptores para citoquinas
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27. COMPONENTES DEL SISTEMA INMUNE 1.2 Los linfocitos se generan y maduran en m édula ósea o en timo
32. An álogo del ácido fólico Conversi ón directa de purinas y pirimidinas a nucleótidos
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35. Linfocitos de B a Efectoras: B de memoria C é lulas plasm á ticas
36. Linfocitos de T a Efectoras: T de ayuda (Th) CD4+ T citot ó xicas (Tc) CD8+ T de memoria
37. NK (CD4 ¯ , CD8 ¯ , CD16+) **No hay NK de memoria**
38. Por hoy, basta. Pr óxima clase: Organos linfoides periféricos Macrófagos y APCs
Notas del editor
Selling your ideas is challenging. First, you must get your listeners to agree with you in principle. Then, you must move them to action. Use the Dale Carnegie Training® Evidence – Action – Benefit formula, and you will deliver a motivational, action-oriented presentation.
Open your presentation with an attention-getting incident. Choose an incident your audience relates to. The incidence is the evidence that supports the action and proves the benefit. Beginning with a motivational incident prepares your audience for the action step that follows.
Next, state the action step. Make your action step specific, clear and brief. Be sure you can visualize your audience taking the action. If you can’t, they can’t either. Be confident when you state the action step, and you will be more likely to motivate the audience to action.
To complete the Dale Carnegie Training® Evidence – Action – Benefit formula, follow the action step with the benefits to the audience. Consider their interests, needs, and preferences. Support the benefits with evidence; i.e., statistics, demonstrations, testimonials, incidents, analogies, and exhibits and you will build credibility.
To close, restate the action step followed by the benefits. Speak with conviction and confidence, and you will sell your ideas.