Lesiones rádicas Intestinales

LESIONES RÁDICAS DEL TUBO DIGESTIVO Raquel García Gómez MIR-1 Oncología Radioterápica. CHPC. Enero 2012.

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

DEFINICIÓN ,[object Object],Hong JJ, Park W, Ehrenpreis ED. Review article: Current therapeutic options for radiation proctopathy. Aliment Pharmacol Ther 2001 Sep 15(9):1253-62.

FACTORES PREDISPONENTES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

DOSIS RT TD5/5 TD50/5 ,[object Object],[object Object],[object Object],[object Object],Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno Normal Tissue Tolerance Dose Metrics for Radiation Therapy of Major Organs. Michael T. Milano , MD, PhD , Louis S. Constine , MD, Paul Okunieff ,MD Department of Radiation Oncology and James P. Wilmot Cancer Center, University of Rochester School of Medicine and Dentistry, Rochester, NY. ¡¡MARGEN ESTRECHO!!

DOSIS RT actualizadas: Art. QUANTEC (ASTRO) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],RADIATION DOSE-VOLUME EFFECTS IN THE ESOPHAGUSInt. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S86–S93, 2010. Elsevier Inc. RADIATION DOSE–VOLUME EFFECTS IN THE STOMACH AND SMALL BOWEL. J. Radiation Oncology Biol. Phys., Vol. 73, No. 3, Supplement, pp. S86–S93, 2010. Elsevier Inc. RADIATION DOSE–VOLUME EFFECTS IN RADIATION-INDUCED RECTAL INJURY. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S86–S93, 2010. Elsevier Inc.

FACTORES PREVENCIÓN ,[object Object],[object Object],[object Object],UpToDate. Incidence and prevention of radiation proctitis. Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

Datos de toxicidad PROCTITIS G ≥2 SANGRADO RECTAL G ≥2 TOX. GU G ≥2 IGRT 4,17% 2,08% 8,33% 3DRTE 19,56% 15,21% 15,2%

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],UpToDate. Incidence and prevention of radiation proctitis. Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

ETIOPATOGENIA/CLÍNICA ,[object Object],[object Object],Diarrea malabsortiva, anemización, traslocación bacteriana, dolor abdominal cólico, náuseas. AUTOLIMITADAS MEDIDAS DE SOPORTE UpToDate. Clinical features, diagnosis, and treatment of radiation proctitis. Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

[object Object],[object Object],I. DELGADO: Oclusión intestinal por estenosis, perforación, abscesos intrabdominales, fístulas, sobrecrecimiento bacteriano, sangrados o malabsorción. I. GRUESO: (+frec RECTO-SIGMA) Diarrea con tenesmo, urgencia defecatoria, hematoquecia y rectorragias. UpToDate. Clinical features, diagnosis, and treatment of radiation proctitis. Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

DIAGNÓSTICO ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Episodios agudos Perforación UpToDate. Clinical features, diagnosis, and treatment of radiation proctitis. Cirugia AEC/ AEC Surgery. Pascual Parrilla,Eduardo Jaurrieta,J. Garcia Landa,Mariano Azcoitia Moreno

E. CRÓNICAS-IMAGEN ENDOSCÓPICA Mucosa granular, friable, edematosa, pálida con telangiectasias submucosas.

VALORACIÓN ENDOSCÓPICA GRADOS PROCTITIS ( Score Saunders ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A. (Ligera: 2) B. (Moderada: 3) C. (Severa: 4/5)

[object Object],[object Object],MANEJO TERAPÉUTICO

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],Canard JM, Vedrenne B, Bors G, et al. Long term results of hemorrhagic proctitis by argon beam coagulation.Gastroenterol Clin Biol 2003;27:447–9.

[object Object],[object Object],[object Object],Canard JM, Vedrenne B, Bors G, et al. Long term results of hemorrhagic proctitis by argon beam coagulation.Gastroenterol Clin Biol 2003;27:447–9

[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],2C : Outcomes research: estudios de cohortes de pacientes con el mismo diagnóstico en los que se relacionan los eventos que suceden con las medidas terapéuticas que reciben. Estudios ecológicos.

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Lesiones rádicas Intestinales

Recomendados

Recomendados

Más contenido relacionado

La actualidad más candente

La actualidad más candente (20)

Similar a Lesiones rádicas Intestinales

Similar a Lesiones rádicas Intestinales (20)

Último

Último (20)

Lesiones rádicas Intestinales