1. Hantavirus: Fisiopatología y Modo de transmisión Juan Carlos Celis Salinas Hospital Regional de Loreto-Iquitos-Peru Infectologo/Tropicalista Grupo de Investigación Peruano de Enfermedades Infecciosas y Tropicales
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3. Transmisión de Hantaviruses Center for Food Security and Public Health Iowa State University - 2004 Roedores infectados crónicamente Virus presente en excreta aerosolizada, particularmente orina Trasmisión horizontal entre la misma especie por contacto Aerosoles secundarios, contacto con membranas mucosas, erosiones piel son también una consideración
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6. B integrinas: rol como receptores del virus y en migración endotelial La unión a las B3 integrinas altera la migración de las células andoteliales dirigida por integrinas, que es esencial para la integridad vascular.
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8. Modelo de la respuesta inmune relacionada a la patogénesis del SPH
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11. Recursos Bibliográficos: hantavirus A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease. CLINICAL MICROBIOLOGY REVIEWS, Apr. 2010, p. 412–441 Hantavirus cardiopulmonary syndrome: immune response and pathogenesis. Microbes and Infection 8 (2006) 2324-2330 Hantavirus Pulmonary Syndrome. Infect Dis Clin N Am 24 (2010) 159–173 Hantaviruses. Clin Lab Med 30 (2010) 67–91 Recent Advances in Hantavirus Molecular Biology and Disease. Advances in Applied Microbiology, Volume 74 (2011) 35-75
Notas del editor
Transmission occurs through inhalation of aerosolized virus particles from rodent excrement. Transmission of hantavirus infection starts with the reservoir host, a chronically infected rodent. Rodents shed the viral particles in their urine, feces, and saliva. Humans become infected when they disturb the microenvironment of rodents and breathe the tiny droplets in the air of these infected particles, a process called aerosolization. Direct contact with rodent excreta on human mucous membranes or through skin abrasions may also result in transmission. The virus particles can contaminate food consumed by humans and cause infection, and in very rare cases, a bite from an infected rodent can precipitate the disease. Horizontal transmission occurs between rodents of the same species and to man. Vertical transmission is negligible or absent and infection is asymptomatic and not deleterious to the rodent reservoir.
For more information on the USPSTF Screening for HIV recommendations, go to: http://www.uspreventiveservicestaskforce.org/uspstf/uspshivi.htm.