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- 1. 1 Una forma de identificar y prevenir factores de riesgo en adolescentes de nivel secundaria entre las edades de 13 a 16 años para disminuir los posibles casos de aterosclerosis. Lorem ipsum more info Ilse E. Alarcón Jiménez Larissa I. Lugo Novoa Emilio S. Bosch Schwarz Fabián Lezama Beltrán Diana A. Hernández Silva Albar Arvizu Contreras Alysha S. Hernández Montiel Erika M. Hernández Montiel Luis D. Alcaraz Vega Jorge Cervantes Gutiérrez Alan Castro Mejia A01128332 A01213961 A01020079 A01211869 A01015441 A01200561 A01184312 A01389036 A01334944 A01334129 A01334188 Ingeniero en Biotecnología Ingeniero en Biotecnología Ingeniero en Biotecnología Ingeniero en Biotecnología Ingeniero en Biotecnología Licenciado en Nutrición y Bienestar Integral Medico Cirujano Medico Cirujano Medico Cirujano Medico Cirujano Medico Cirujano ® Derechos Reservados
- 2. Equipo 4 2 Introducción Semana de la Innovación: Cardiopatía Isquemica 32 41 ATEROESCLEROSIS Estrés oxidativo y existencia de PON1 PON1 Estereasa plasmática. Evita peroxidación de liporoteínas (HDL y LDL) ENSANUT Obesidad en niños aumenta del 18% al 34.4 % de 1999 al 2012. SOBREPESO Y OBESIDAD En la niñez y adolescencia: Factor de riesgo importante en mortalidad en la vida adulta ® Derechos Reservados
- 3. Equipo 4 3 Introducción: Factor de Riesgo Semana de la Innovación: Cardiopatía Isquemica Referencias: 1. Cronenwett, J. (2014) Rutherford's Vascular Surgery, Eighth Edition. ELSEVIER. Recuperado de: https://0-www.clinicalkey.com.millenium.itesm.mx/#!/browse/book/3-s2.0- C20110077141 Fig 2. Desarrollo de ateroesclerosis en arterias coronarias Fig 1. Daño endotelial ® Derechos Reservados
- 4. Equipo 4 4 Introducción Semana de la Innovación: Cardiopatía Isquemica Referencias: 1. Tomás, M., Latorre, G., Sentí, M., & Marrugat, J. (2004). Función antioxidante de las lipoproteínas de alta densidad: un nuevo paradigma en la arteriosclerosis. Revista Española de Cardiología, 57(6), 557–569. doi:10.1016/s0300-8932(04)77146-8 Fig 3 Vía metabólica de lipoproteínas y PON1 ® Derechos Reservados
- 5. Equipo 4 5 Soluciones existentes Semana de la Innovación: Cardiopatía Isquemica Referencias: 1. AHA. (2014). National Institutes of Health. Recuperado el 4 de Noviembre de 2014, de What Is the DASH Eating Plan? : http://www.nhlbi.nih.gov/health/health- topics/topics/dash/ 2. Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., ... & Cutler, J. A. (2001). Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. New England journal of medicine, 344(1), 3-10. 3. MyPyramid.gov - United States Department of Agriculture - Home. Web. 03 Feb. 2011. <http://www.mypyramid.gov/>. Fig 5. La Pirámide alimentaria Fig 4. Dieta DASH ® Derechos Reservados
- 6. Equipo 4 6 Soluciones existentes Semana de la Innovación: Cardiopatía Isquemica Referencias: 1. Ministerio de Agricultura, Alimentación y Medio Ambiente (2009). Fundación dieta mediterránea Fundación dieta mediterránea . Recuperado el 3 de Noviembre de 2014, de http://dietamediterranea.com/ 2. Osorio, O. (7 de Junio de 2014). Secretaría de Salud. Recuperado el 6 de Marzo de 2015, de MÁS VALE PREVENIR-CHÉCATE, MÍDETE Y MUÉVETE: http://promocion.salud.gob.mx/dgps/interior1/checate.html 3. Fundación Científica Astra Zéneca. (2013). Salvemos el corazón. Recuperado de: http://www.diamundialdelcorazon.com/2011/09/salvemos-el-corazon-de-las-mujeres/ Fig 5. Campaña IMSS Fig 5. Prevención cardiovascular Fig 5. Dieta Mediterránea ® Derechos Reservados
- 7. Equipo 4 7 Áreas de Oportunidad Semana de la Innovación: Cardiopatía Isquemica ® Derechos Reservados
- 8. Causas de mortalidad en México (2012) : • Enfermedades cardíacas 75.1% • Enfermedad isquémica coronaria 35% La EIC es la primer causa de años perdidos en el país (OMS, 2013). Población a enfocarse: adolescentes de 13-16 años (vulnerabilidad social) Se busca implementar un método no invasivo. Características Equipo 4 8 Propuesta de solución Semana de la Innovación: Cardiopatía Isquemica ® Derechos Reservados
- 9. Equipo 4 9 Propuesta de prototipo Semana de la Innovación: Cardiopatía Isquemica ® Derechos Reservados
- 10. Equipo 4 10 Propuesta de prototipo: Factibilidad Semana de la Innovación: Cardiopatía Isquemica Tiempo de elaboración 6 meses-1 año Factibilidad técnica: • Muestra salival • Tiras reactivas Bajos costos (5000 tiras) • Paciente: menos de 2 dólares • Costo de adquisición: 260 USD ® Derechos Reservados
- 11. Ventajas Desventaja Aplicable a masas Dependes del paciente quiera cambiar Costo accesible No es cuantitativa Tiempo de diagnóstico Sólo ve un factor de riesgo Confiabilidad Precisión Fácil uso No invasiva Nada en el mercado Tecnológico Eficiente Equipo 4 11 Contribución Inovadora Semana de la Innovación: Cardiopatía Isquemica ® Derechos Reservados
- 12. Equipo 4 Isquemia cardiaca. Disminuir el riesgo de isquemia por medio de la aterosclerosis Isquemia -Ateroesclerosis- PON1 Detección de mutaciones de PON1 para identificar población con mayor Precio por unidad ~2 dólares para el paciente Producción Entre 6 meses y 1 año para desarrollar la prueba rápida. 12 Conclusión Semana de la Innovación: Cardiopatía Isquemica Innovación CostoFactibilidad Prevención Meta Concientizar a los padres de familia sobre la importancia de una buena dieta y una cantidad suficiente de ejercicio para sus hijos y por último sugiriendo el consumo de un alimento nutracéutico con concentraciones de PON1 ® Derechos Reservados
- 13. Equipo 4 13 Video Semana de la Innovación: Cardiopatía Isquemica PIC-Strip Diseño: Fabián Lezama Beltrán Equipo 4 ® Derechos Reservados
- 14. Equipo 4 14 Referencias Semana de la Innovación: Cardiopatía Isquemica 1. Cronenwett, J. (2014) Rutherford's Vascular Surgery, Eighth Edition. ELSEVIER. Recuperado de: https://0- www.clinicalkey.com.millenium.itesm.mx/#!/browse/book/3-s2.0-C20110077141 2. Tomás, M., Latorre, G., Sentí, M., & Marrugat, J. (2004). Función antioxidante de las lipoproteínas de alta densidad: un nuevo paradigma en la arteriosclerosis. Revista Española de Cardiología, 57(6), 557–569. doi:10.1016/s0300- 8932(04)77146-8 3. AHA. (2014). National Institutes of Health. Recuperado el 4 de Noviembre de 2014, de What Is the DASH Eating Plan? : http://www.nhlbi.nih.gov/health/health- topics/topics/dash/ 4. Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., ... & Cutler, J. A. (2001). Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. New England journal of medicine, 344(1), 3-10. 5. MyPyramid.gov - United States Department of Agriculture - Home. Web. 03 Feb. 2011. <http://www.mypyramid.gov/>. 6. Ministerio de Agricultura, Alimentación y Medio Ambiente (2009). Fundación dieta mediterránea Fundación dieta mediterránea . Recuperado el 3 de Noviembre de 2014, de http://dietamediterranea.com/ 7. Osorio, O. (7 de Junio de 2014). Secretaría de Salud. Recuperado el 6 de Marzo de 2015, de MÁS VALE PREVENIR- CHÉCATE, MÍDETE Y MUÉVETE: http://promocion.salud.gob.mx/dgps/interior1/checate.html 8. Fundación Científica Astra Zéneca. (2013). Salvemos el corazón. Recuperado de: http://www.diamundialdelcorazon.com/2011/09/salvemos-el-corazon-de-las-mujeres/ ® Derechos Reservados
Notas del editor
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- To control which of the arches animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this) In this slide, you could for examle use the two arches around the quote and the middle two arches from the footer for a MagicMove. To do so, just select the second and third arch in the footer and group them together.
- The following 4 slides are pretty much the same. But the position & colour for the 4 parts of the image frame are different. To change the image: double-click the image and THEN drag & drop a new image in from your desktop. (Make sure you double-click near the image centre, so not to select the coloured border). For the same reason, the paragraph text is grouped together with the line. To edit the text, double click it first. If you don’t like the line, make it 100% transparent. The “Disappear” Group is the 4 parts grouped together into one object (which will dissolve onto the stage during a MagicMove animation FROM the previous slide). The four “Appear” objects are individual objects. They Appear before the grouped frame disappears, and serve to facilitate MagicMove on the next slides.
- The following 4 slides are pretty much the same. But the position & colour for the 4 parts of the image frame are different. To change the image: double-click the image and THEN drag & drop a new image in from your desktop. (Make sure you double-click near the image centre, so not to select the coloured border). For the same reason, the paragraph text is grouped together with the line. To edit the text, double click it first. If you don’t like the line, make it 100% transparent. The “Disappear” Group is the 4 parts grouped together into one object (which will dissolve onto the stage during a MagicMove animation FROM the previous slide). The four “Appear” objects are individual objects. They Appear before the grouped frame disappears, and serve to facilitate MagicMove on the next slides.
- The following 4 slides are pretty much the same. But the position & colour for the 4 parts of the image frame are different. To change the image: double-click the image and THEN drag & drop a new image in from your desktop. (Make sure you double-click near the image centre, so not to select the coloured border). For the same reason, the paragraph text is grouped together with the line. To edit the text, double click it first. If you don’t like the line, make it 100% transparent. The “Disappear” Group is the 4 parts grouped together into one object (which will dissolve onto the stage during a MagicMove animation FROM the previous slide). The four “Appear” objects are individual objects. They Appear before the grouped frame disappears, and serve to facilitate MagicMove on the next slides.
- The following 4 slides are pretty much the same. But the position & colour for the 4 parts of the image frame are different. To change the image: double-click the image and THEN drag & drop a new image in from your desktop. (Make sure you double-click near the image centre, so not to select the coloured border). For the same reason, the paragraph text is grouped together with the line. To edit the text, double click it first. If you don’t like the line, make it 100% transparent. The “Disappear” Group is the 4 parts grouped together into one object (which will dissolve onto the stage during a MagicMove animation FROM the previous slide). The four “Appear” objects are individual objects. They Appear before the grouped frame disappears, and serve to facilitate MagicMove on the next slides.
- To control which of the arches or arrows animate with a Magic Move: simply select the ones you DON’T want to animate and group them. If they are already grouped and you DO want to animate them with a Magic Move: UNgroup them. For MagicMove animations: always make sure the arches on the NEXT slide are not grouped, and also don’t have a “Build In” effect assigned to them. (Check the Build Order for this)
- The following 4 slides are pretty much the same. But the position & colour for the 4 parts of the image frame are different. To change the image: double-click the image and THEN drag & drop a new image in from your desktop. (Make sure you double-click near the image centre, so not to select the coloured border). For the same reason, the paragraph text is grouped together with the line. To edit the text, double click it first. If you don’t like the line, make it 100% transparent. The “Disappear” Group is the 4 parts grouped together into one object (which will dissolve onto the stage during a MagicMove animation FROM the previous slide). The four “Appear” objects are individual objects. They Appear before the grouped frame disappears, and serve to facilitate MagicMove on the next slides.