Ehfn2 11 06

ENFERMEDAD HEMOLITICA FETO NEONATAL Dra. Fabiana Bastos Departamento de Hemoterpia e Inmunohematología Hospital de Clínicas “José de San Martín” [email_address]

DEFINICION ,[object Object],[object Object],[object Object],[object Object],[object Object]

RESEÑA HISTORICA ,[object Object],[object Object],[object Object],[object Object]

FISIOPATOLOGIA ,[object Object],[object Object],[object Object]

CAUSAS SENSIBILIZACION ,[object Object]

CAUSAS SENSIBILIZACION ,[object Object],[object Object],[object Object],[object Object],[object Object]

CAUSAS SENSIBILIZACION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEMORRAGIA FETO MATERNA ,[object Object],[object Object]

HEMORRAGIA FETO MATERNA ,[object Object],[object Object],[object Object],[object Object]

HEMORRAGIA FETO MATERNA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ANTICUERPOS IMPLICADOS anti- M, N, S y s MNSs anti- Jka y Jkb Kidd anti- Fya Duffy anti- K y k Kell anti-AB (en madre O) ABO anti-D, C, E, c y e Rh ANTICUERPOS SISTEMA

ANTICUERPOS IMPLICADOS ,[object Object],[object Object],[object Object]

RIESGO DE INMUNIZACION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CAUSAS SENSIBILIZACION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CAUSAS SENSIBILIZACION ,[object Object],[object Object],[object Object],[object Object]

CAUSAS ,[object Object],[object Object],[object Object]

TIPO DE INMUNOGLOBULINA ,[object Object],[object Object],[object Object],[object Object],[object Object]

TIPO DE INMUNOGLOBULINA ,[object Object],[object Object],[object Object],[object Object]

EHFN ABO ,[object Object],[object Object],[object Object],[object Object]

Circulación Fetal Circulación Materna

Circulación Materna Circulación Fetal

HEMOLISIS ANEMIA  ERITROPOYESIS HIGADO BAZO MO PIEL PLACENTA HEPATOSIS HIPOXIA INSUFICIENCIA CARDIACA MIOCARDOSIS HIPOPROTEINEMIA EDEMA HIDROPS MUERTE FETAL INSUFICIENCIA PLACENTARIA HIPERBILIRRUBINEMIA

ESTUDIOS PRENATALES ,[object Object],[object Object],[object Object],[object Object]

ESTUDIOS PRENATALES ,[object Object],[object Object],[object Object],[object Object],[object Object]

ESTUDIOS PRENATALES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TRATAMIENTO PRENATAL ,[object Object],[object Object],[object Object],[object Object]

DAI POSITIVA SIN ANTECEDENTES DE EHFN

TITULO ,[object Object],[object Object],[object Object]

TITULO ,[object Object],[object Object],[object Object],[object Object]

TEST DE LILEY ,[object Object],[object Object],[object Object],[object Object]

TEST DE LILEY ,[object Object],[object Object],[object Object]

TEST DE LILEY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

DAI POSITIVA CON ANTECEDENTES DE HIDROPS O FETO MUERTO

TRATAMIENTO ,[object Object],[object Object]

CUALQUIER TITULO ,[object Object],[object Object],[object Object]

TEST DE LILEY ,[object Object],[object Object]

TIU ,[object Object],[object Object],[object Object]

TIU ,[object Object],[object Object],[object Object],[object Object]

TIPOS DE TIU ,[object Object],[object Object],[object Object],[object Object]

COMPLICACIONES TIU ,[object Object],[object Object],[object Object],[object Object]

COMPLICACIONES TIU ,[object Object],[object Object],[object Object],[object Object],[object Object]

ESTUDIOS POSNATALES ,[object Object],[object Object],[object Object],[object Object],[object Object]

ESTUDIOS POSNATALES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SEVERIDAD EHFN ,[object Object],[object Object],[object Object]

SEVERIDAD EHFN ,[object Object],[object Object],[object Object],[object Object]

TRATAMIENTO ,[object Object],[object Object],[object Object]

HIPERBILIRRUBINEMIA ,[object Object],[object Object]

HIPERBILIRRUBINEMIA ,[object Object],[object Object],[object Object]

ENCEFALOPATIA BI ,[object Object],[object Object],[object Object],[object Object]

FOTOTERAPIA ,[object Object],[object Object],[object Object],[object Object],[object Object]

FOTOTERAPIA >15 >14 >12 >10 >3.5 Bilirrubina g/dl 2-3 días < 24 hs <18 hs <12 hs cordón Edad

EXANGUINOTRANFUSION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

EXANGUINOTRANFUSION ,[object Object],[object Object],[object Object],[object Object]

EXANGUINOTRANFUSION <1250 gr > 9-12 1250-1499 gr >13 1500-1999 gr >15 2000-2499 gr >17 Séptico >2500 gr >18 Sano > 2500 gr >20 Peso Bilirrubina g/dl

EXANGUINOTRANFUSION ,[object Object],[object Object],[object Object],[object Object],[object Object]

PROFILAXIS ,[object Object],[object Object],[object Object],[object Object]

PROFILAXIS ,[object Object],[object Object],[object Object],[object Object],[object Object]

PROFILAXIS ,[object Object],[object Object],[object Object]

PROFILAXIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RECORDAR ,[object Object],[object Object]

Ehfn2 11 06

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Ehfn2 11 06