El documento describe el cáncer de trompa de Falopio, incluyendo su epidemiología, manifestaciones clínicas, diagnóstico, estadificación y tratamiento. Es un cáncer raro que representa menos del 1% de los cánceres ginecológicos, asociado con mutaciones BRCA y factores como nuliparidad. Los síntomas incluyen hemorragia vaginal, dolor abdominal y masa pélvica. El diagnóstico se realiza mediante ultrasonido, RNM y biopsia. Se estadifica según FIGO y el tratamiento

1. C áncer de la Trompa de Falopio Gregorio Urruela Vizcaíno Residente II

15. Estadíos según la FIGO: Growth involving one or both fallopian tubes, with distant metastases. If pleural effusion is present, there must be positive cytology to be stage IV. Parenchymal liver metastases equals stage IV. IV Abdominal implants >2 cm in diameter or positive retroperitoneal or inguinal nodes. IIIc Tumor involving one or both tubes, with histologically confirmed implants of abdominal peritoneal surfaces, none exceeding 2 cm in diameter. Lymph nodes are negative. IIIb Tumor is grossly limited to the true pelvis, with negative nodes but with histologically confirmed microscopic seeding of abdominal peritoneal surfaces. IIIa Tumor involves one or both fallopian tubes, with peritoneal implants outside the pelvis or positive retroperitoneal or inguinal nodes. Superficial liver metastasis equals stage III. Tumor appears limited to the true pelvis but with histologically proven malignant extension to the small bowel or omentum. III Tumor stage IIa or IIb, with ascites present containing malignant cells or with positive peritoneal washings. IIc Extension to other pelvic tissues. IIb Extension or metastasis to the uterus or ovaries. IIa Growth involving one or both fallopian tubes, with pelvic extension. II Tumor stage Ia or Ib but with tumor extension through or on to the tubal serosa; or with ascites present containing malignant cells, or with positive peritoneal washings. Ic Growth is limited to both tubes, with extension into the submucosa or muscularis but not penetrating the serosal surface; no ascites. Ib Growth is limited to one tube, with extension into the submucosa or muscularis but not penetrating the serosal surface; no ascites. Ia Growth limited to the fallopian tubes. I Carcinoma in situ (limited to tubal mucosa). 0 Definición Estadío

17. Pronóstico INTERNATIONAL FEDERATION OF GYNECOLOGY AND OBSTETRICS STAGING 69 — 103 — — 334 Overall 29 6.8 7 45 45.2 151 IV 60 34.0 35 69 15.6 52 III 82 16.5 17 75 8.7 29 II 79 40.8 42 95 30.5 102 I Five-year survival (%) % of cases No. of patients Five-year survival (%) % of all cases No. of patients Stage Heintz et al (2003) Kosary and Trimble (2002)